Journal
VISION RESEARCH
Volume 73, Issue -, Pages 30-39Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.visres.2012.09.002
Keywords
Myopia; Form deprivation; Peripheral refractive error; Peripheral hyperopia; Ocular shape
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Funding
- NIH [EY-03611, EY-07551]
- Vision Cooperative Research Centre, Sydney, Australia
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This study aimed to investigate the changes in ocular shape and relative peripheral refraction during the recovery from myopia produced by form deprivation (FD) and hyperopic defocus. FD was imposed in six monkeys by securing a diffuser lens over one eye; hyperopic defocus was produced in another six monkeys by fitting one eye with 3 D spectacle. When unrestricted vision was re-established, the treated eyes recovered from the vision-induced central and peripheral refractive errors. The recovery of peripheral refractive errors was associated with corresponding changes in the shape of the posterior globe. The results suggest that vision can actively regulate ocular shape and the development of central and peripheral refractions in infant primates. (C)2012 Elsevier Ltd. All rights reserved.
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