Journal
VIRUS RESEARCH
Volume 137, Issue 1, Pages 150-152Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.virusres.2008.06.011
Keywords
acute hemorrhagic conjunctivitis; etiological agent; coxsackievirus A24 variant; Pakistan
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Acute hemorrhagic conjunctivitis (AHC) is a self-limiting viral infection of the eyes but having epidemic potential. In winter 2004-2005, an outbreak of acute hemorrhagic conjunctivitis (AHC) occurred in Islamabad, Pakistan. The etiological agent was confirmed as coxsackievirus A24 variant (CA24v) by virus isolation and sequencing of a part of the VP1/VP3 gene. Phylogenetic analysis in VP1 region showed that Pakistan isolates has closest matches both in Asia and Europe while in VP1/VP3 region they were more closely related to Chinese strains, suggesting their common source in Asia which is constantly evolving to cause AHC outbreaks in susceptible hosts in different parts of the world. (C) 2008 Elsevier B.V. All rights reserved.
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