Inhibition of cyclophilins alters lipid trafficking and blocks hepatitis C virus secretion

Mechanism of Resistance of Hepatitis C Virus Replicons to Structurally Distinct Cyclophilin Inhibitors

(2010) X. Puyang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Apolipoprotein B100 biogenesis: a complex array of intracellular mechanisms regulating folding, stability, and lipoprotein assemblyThis paper is one of a selection of papers published in this special issue entitled “Canadian Society of Biochemistry, Molecular & Cellular Biology 52nd Annual Meeting — Protein Folding: Principles and Diseases” and has undergone the Journal's usual peer review process.

(2010) Angela C. Rutledge et al.   Biochemistry and Cell Biology

Cyclosporine A inhibits hepatitis C virus nonstructural protein 2 through cyclophilin A

(2009) Sandra Ciesek et al.   HEPATOLOGY

The Isomerase Active Site of Cyclophilin A Is Critical for Hepatitis C Virus Replication

(2009) Udayan Chatterji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatitis C Virus Nonstructural 4B Protein Modulates Sterol Regulatory Element-binding Protein Signaling via the AKT Pathway

(2009) Chul-Yong Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-structural 5A protein of hepatitis C virus induces a range of liver pathology in transgenic mice

(2009) Ai-Guo Wang et al.   JOURNAL OF PATHOLOGY

Determinants of the Hepatitis C Virus Nonstructural Protein 2 Protease Domain Required for Production of Infectious Virus

(2009) T. G. Dentzer et al.   JOURNAL OF VIROLOGY

Multiple cyclophilins involved in different cellular pathways mediate HCV replication

(2009) L. Alex Gaither et al.   VIROLOGY

Combinations of Cyclophilin Inhibitor NIM811 with Hepatitis C Virus NS3-4A Protease or NS5B Polymerase Inhibitors Enhance Antiviral Activity and Suppress the Emergence of Resistance

(2008) J. E. Mathy et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Lipid droplets are arrested in the ER membrane by tight binding of lipidated apolipoprotein B-100

(2008) Y. Ohsaki et al.   JOURNAL OF CELL SCIENCE

Cyclophilin A Is an Essential Cofactor for Hepatitis C Virus Infection and the Principal Mediator of Cyclosporine Resistance In Vitro

(2008) F. Yang et al.   JOURNAL OF VIROLOGY