Sample parameters affecting the clinical relevance of RNA biomarkers in translational breast cancer research

A Three-Gene Model to Robustly Identify Breast Cancer Molecular Subtypes

(2012) Benjamin Haibe-Kains et al.   JNCI-Journal of the National Cancer Institute

HER2 and TOP2A in high-risk early breast cancer patients treated with adjuvant epirubicin-based dose-dense sequential chemotherapy.

(2012) George Fountzilas et al.   Journal of Translational Medicine

Decentral gene expression analysis for ER+/Her2− breast cancer: results of a proficiency testing program for the EndoPredict assay

(2012) Carsten Denkert et al.   VIRCHOWS ARCHIV

Prognostic significance of UBE2C mRNA expression in high-risk early breast cancer. A Hellenic Cooperative Oncology Group (HeCOG) Study

(2011) A. Psyrri et al.   ANNALS OF ONCOLOGY

Is gene array testing to be considered routine now?

(2011) Soonmyung Paik   BREAST

Prognostic utility of β-tubulin isotype III and correlations with other molecular and clinicopathological variables in patients with early breast cancer: a translational Hellenic Cooperative Oncology Group (HeCOG) study

(2011) George Pentheroudakis et al.   BREAST CANCER RESEARCH AND TREATMENT

Triple-negative phenotype is of adverse prognostic value in patients treated with dose-dense sequential adjuvant chemotherapy: a translational research analysis in the context of a Hellenic Cooperative Oncology Group (HeCOG) randomized phase III trial

(2011) P. Skarlos et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Gene Expression Profiles from Formalin Fixed Paraffin Embedded Breast Cancer Tissue Are Largely Comparable to Fresh Frozen Matched Tissue

(2011) Lorenza Mittempergher et al.   PLoS One

Combination of osteopontin and activated leukocyte cell adhesion molecule as potent prognostic discriminators in HER2- and ER-negative breast cancer

(2010) M Ihnen et al.   BRITISH JOURNAL OF CANCER

Clinical evaluation of developed PCR-based method with hydrolysis probes for TOP2A copy number evaluation in breast cancer samples

(2010) Anna Żaczek et al.   CLINICAL BIOCHEMISTRY

ERBB2 and TOP2A in Breast Cancer: A Comprehensive Analysis of Gene Amplification, RNA Levels, and Protein Expression and Their Influence on Prognosis and Prediction

(2010) J. C. Brase et al.   CLINICAL CANCER RESEARCH

Gene Expression Profiles of Estrogen Receptor-Positive and Estrogen Receptor-Negative Breast Cancers Are Detectable in Histologically Normal Breast Epithelium

(2010) K. Graham et al.   CLINICAL CANCER RESEARCH

Automated Extraction of DNA and RNA from a Single Formalin-Fixed Paraffin-Embedded Tissue Section for Analysis of Both Single-Nucleotide Polymorphisms and mRNA Expression

(2010) G. Hennig et al.   CLINICAL CHEMISTRY

A Comparison of HER2/neu Gene Amplification and Its Protein Overexpression Between Primary Breast Cancer and Metastatic Lymph Nodes

(2010) Kei Aoyama et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Intratumor Heterogeneity and Precision of Microarray-Based Predictors of Breast Cancer Biology and Clinical Outcome

(2010) William T. Barry et al.   JOURNAL OF CLINICAL ONCOLOGY

American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Immunohistochemical Testing of Estrogen and Progesterone Receptors in Breast Cancer

(2010) M. Elizabeth H. Hammond et al.   JOURNAL OF CLINICAL ONCOLOGY

Concordance between HER-2 and steroid hormone receptor expression between primary breast cancer, sentinel node metastases, and isolated tumor cells

(2010) Leena Strien et al.   PATHOLOGY RESEARCH AND PRACTICE

Does Analysis of Biomarkers in Tumor Cells in Lymph Node Metastases Give Additional Prognostic Information in Primary Breast Cancer?

(2010) Anna-Karin Falck et al.   WORLD JOURNAL OF SURGERY

Quantitative analysis of changes in ER, PR and HER2 expression in primary breast cancer and paired nodal metastases

(2009) S. J. Aitken et al.   ANNALS OF ONCOLOGY

Relationship between Topoisomerase 2A RNA Expression and Recurrence after Adjuvant Chemotherapy for Breast Cancer

(2009) J. A. Sparano et al.   CLINICAL CANCER RESEARCH

RNA Extraction from Archival Formalin-Fixed Paraffin-Embedded Tissue: A Comparison of Manual, Semiautomated, and Fully Automated Purification Methods

(2009) K. Bohmann et al.   CLINICAL CHEMISTRY

Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues

(2009) Angela B Y Hui et al.   LABORATORY INVESTIGATION

Targeted KRAS Mutation Assessment on Patient Tumor Histologic Material in Real Time Diagnostics

(2009) Vassiliki Kotoula et al.   PLoS One

Gene expression variation between distinct areas of breast cancer measured from paraffin-embedded tissue cores

(2008) Martina Schobesberger et al.   BMC CANCER

Gene expression of estrogen receptor, progesterone receptor and microtubule-associated protein Tau in high-risk early breast cancer: a quest for molecular predictors of treatment benefit in the context of a Hellenic Cooperative Oncology Group trial

(2008) George Pentheroudakis et al.   BREAST CANCER RESEARCH AND TREATMENT

Evaluation of the prognostic and predictive value of HER family mRNA expression in high-risk early breast cancer: A Hellenic Cooperative Oncology Group (HeCOG) study

(2008) A K Koutras et al.   BRITISH JOURNAL OF CANCER

CUX1 and E2F1 Regulate Coordinated Expression of the Mitotic Complex Genes Ect2, MgcRacGAP, and MKLP1 in S Phase

(2008) L. Seguin et al.   MOLECULAR AND CELLULAR BIOLOGY

Stromal gene expression predicts clinical outcome in breast cancer

(2008) Greg Finak et al.   NATURE MEDICINE