The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies

The Caenorhabditis elegans protein SAS-5 forms large oligomeric assemblies critical for centriole formation

(2015) Kacper B Rogala et al.   eLife

Plk4-dependent phosphorylation of STIL is required for centriole duplication

(2015) A.-S. Kratz et al.   Biology Open

Plk4 Phosphorylates Ana2 to Trigger Sas6 Recruitment and Procentriole Formation

(2014) Nikola S. Dzhindzhev et al.   CURRENT BIOLOGY

The Centrosome-Specific Phosphorylation of Cnn by Polo/Plk1 Drives Cnn Scaffold Assembly and Centrosome Maturation

(2014) Paul T. Conduit et al.   DEVELOPMENTAL CELL

SAS-6 Assembly Templated by the Lumen of Cartwheel-less Centrioles Precedes Centriole Duplication

(2014) Chii Shyang Fong et al.   DEVELOPMENTAL CELL

The Mechanism of Dynein Light Chain LC8-mediated Oligomerization of the Ana2 Centriole Duplication Factor

(2014) Lauren K. Slevin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of HsSAS-6 assembly promoting centriole formation in human cells

(2014) Debora Keller et al.   JOURNAL OF CELL BIOLOGY

Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis

(2014) Suk-Youl Park et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the C. elegans ZYG-1 Cryptic Polo Box Suggests a Conserved Mechanism for Centriolar Docking of Plk4 Kinases

(2014) Ekaterina Shimanovskaya et al.   STRUCTURE

Direct interaction of Plk4 with STIL ensures formation of a single procentriole per parental centriole

(2014) Midori Ohta et al.   Nature Communications

Structure of the SAS-6 cartwheel hub from Leishmania major

(2014) Mark van Breugel et al.   eLife

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Native Architecture of the Centriole Proximal Region Reveals Features Underlying Its 9-Fold Radial Symmetry

(2013) Paul Guichard et al.   CURRENT BIOLOGY

Direct Binding of SAS-6 to ZYG-1 Recruits SAS-6 to the Mother Centriole for Cartwheel Assembly

(2013) Molly M. Lettman et al.   DEVELOPMENTAL CELL

Human microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assembly

(2013) Yu-Chih Lin et al.   EMBO JOURNAL

Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication

(2013) K. F. Sonnen et al.   JOURNAL OF CELL SCIENCE

Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry

(2013) M. Hilbert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds, Cep192 and Cep152

(2013) T.-S. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Analysis of the G-Box Domain of the Microcephaly Protein CPAP Suggests a Role in Centriole Architecture

(2013) Georgios N. Hatzopoulos et al.   STRUCTURE

Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly

(2013) Matthew A Cottee et al.   eLife

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

BLD10/CEP135 Is a Microtubule-Associated Protein that Controls the Formation of the Flagellum Central Microtubule Pair

(2012) Zita Carvalho-Santos et al.   DEVELOPMENTAL CELL

SAS-6 coiled-coil structure and interaction with SAS-5 suggest a regulatory mechanism inC. eleganscentriole assembly

(2012) Renping Qiao et al.   EMBO JOURNAL

Drosophila Cep135/Bld10 maintains proper centriole structure but is dispensable for cartwheel formation

(2012) H. Roque et al.   JOURNAL OF CELL SCIENCE

Cell-cycle-regulated expression of STIL controls centriole number in human cells

(2012) C. Arquint et al.   JOURNAL OF CELL SCIENCE

STIL is required for centriole duplication in human cells

(2012) J. Vulprecht et al.   JOURNAL OF CELL SCIENCE

Subdiffraction-resolution fluorescence microscopy reveals a domain of the centrosome critical for pericentriolar material organization

(2012) V. Mennella et al.   NATURE CELL BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Towards a molecular architecture of centriole assembly

(2012) Pierre Gönczy   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cartwheel Architecture of Trichonympha Basal Body

(2012) P. Guichard et al.   SCIENCE

The Structure of the Plk4 Cryptic Polo Box Reveals Two Tandem Polo Boxes Required for Centriole Duplication

(2012) Lauren K. Slevin et al.   STRUCTURE

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Basis of the 9-Fold Symmetry of Centrioles

(2011) Daiju Kitagawa et al.   CELL

An Ana2/Ctp/Mud Complex Regulates Spindle Orientation in Drosophila Neuroblasts

(2011) Cheng Wang et al.   DEVELOPMENTAL CELL

The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation

(2011) Chieh-Ju C Tang et al.   EMBO JOURNAL

SAS-6 oligomerization: the key to the centriole?

(2011) Matthew A Cottee et al.   Nature Chemical Biology

Structures of SAS-6 Suggest Its Organization in Centrioles

(2011) M. van Breugel et al.   SCIENCE

Centrosomes and cilia in human disease

(2011) Mónica Bettencourt-Dias et al.   TRENDS IN GENETICS

Recent developments in classical density modification

(2010) Kevin Cowtan   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Centrioles Regulate Centrosome Size by Controlling the Rate of Cnn Incorporation into the PCM

(2010) Paul T. Conduit et al.   CURRENT BIOLOGY

DSas-6 and Ana2 Coassemble into Tubules to Promote Centriole Duplication and Engagement

(2010) Naomi R. Stevens et al.   DEVELOPMENTAL CELL

Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome

(2010) Onur Cizmecioglu et al.   JOURNAL OF CELL BIOLOGY

DrosophilaAna2 is a conserved centriole duplication factor

(2010) Naomi R. Stevens et al.   JOURNAL OF CELL BIOLOGY

Cep152 interacts with Plk4 and is required for centriole duplication

(2010) Emily M. Hatch et al.   JOURNAL OF CELL BIOLOGY

Asterless is a scaffold for the onset of centriole assembly

(2010) Nikola S. Dzhindzhev et al.   NATURE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Centrioles, Centrosomes, and Cilia in Health and Disease

(2009) Erich A. Nigg et al.   CELL

xia2: an expert system for macromolecular crystallography data reduction

(2009) G. Winter   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Ana3 is a conserved protein required for the structural integrity of centrioles and basal bodies

(2009) Naomi R. Stevens et al.   JOURNAL OF CELL BIOLOGY

Drosophila Bld10 Is a Centriolar Protein That Regulates Centriole, Basal Body, and Motile Cilium Assembly

(2009) Violaine Mottier-Pavie et al.   MOLECULAR BIOLOGY OF THE CELL

Drosophila asterless and Vertebrate Cep152 Are Orthologs Essential for Centriole Duplication

(2008) S. Blachon et al.   GENETICS

CHAINSAW: a program for mutating pdb files used as templates in molecular replacement

(2008) Norman Stein   JOURNAL OF APPLIED CRYSTALLOGRAPHY