Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma
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Title
Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma
Authors
Keywords
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Journal
eLife
Volume 4, Issue -, Pages -
Publisher
eLife Sciences Organisation, Ltd.
Online
2015-06-05
DOI
10.7554/elife.06907
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- (2013) J. Gao et al. Science Signaling
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- (2012) Rebecca S. Heist et al. CANCER CELL
- Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing
- (2012) Marcin Imielinski et al. CELL
- The transcriptional landscape and mutational profile of lung adenocarcinoma
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- Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1
- (2012) K. Ohashi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2012) Ethan Cerami et al. Cancer Discovery
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- The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo
- (2011) Kristen L. Meerbrey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2009) Alejo Efeyan et al. PLoS One
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