CryoEM and computer simulations reveal a novel kinase conformational switch in bacterial chemotaxis signaling

Molecular dynamics simulations of large macromolecular complexes

(2015) Juan R Perilla et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Conical Fourier shell correlation applied to electron tomograms

(2015) C.A. Diebolder et al.   JOURNAL OF STRUCTURAL BIOLOGY

Signaling and sensory adaptation in Escherichia coli chemoreceptors: 2015 update

(2015) John S. Parkinson et al.   TRENDS IN MICROBIOLOGY

fastcluster: Fast Hierarchical, Agglomerative Clustering Routines forRandPython

(2015) Daniel Müllner   Journal of Statistical Software

New Insights into Bacterial Chemoreceptor Array Structure and Assembly from Electron Cryotomography

(2014) Ariane Briegel et al.   BIOCHEMISTRY

Increasing and Decreasing the Ultrastability of Bacterial Chemotaxis Core Signaling Complexes by Modifying Protein−Protein Contacts

(2014) Kene N. Piasta et al.   BIOCHEMISTRY

The Linker between the Dimerization and Catalytic Domains of the CheA Histidine Kinase Propagates Changes in Structure and Dynamics That Are Important for Enzymatic Activity

(2014) Xiqing Wang et al.   BIOCHEMISTRY

Architecture and signal transduction mechanism of the bacterial chemosensory array: Progress, controversies, and challenges

(2014) Joseph J Falke et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Selective allosteric coupling in core chemotaxis signaling complexes

(2014) Mingshan Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Controlled Bacterial Lysis for Electron Tomography of Native Cell Membranes

(2014) Xiaofeng Fu et al.   STRUCTURE

Structure of bacterial cytoplasmic chemoreceptor arrays and implications for chemotactic signaling

(2014) Ariane Briegel et al.   eLife

Quantitative Modeling of Bacterial Chemotaxis: Signal Amplification and Accurate Adaptation

(2013) Yuhai Tu   Annual Review of Biophysics

Defining a Key Receptor–CheA Kinase Contact and Elucidating Its Function in the Membrane-Bound Bacterial Chemosensory Array: A Disulfide Mapping and TAM-IDS Study

(2013) Kene N. Piasta et al.   BIOCHEMISTRY

Structure, Function, and On–Off Switching of a Core Unit Contact between CheA Kinase and CheW Adaptor Protein in the Bacterial Chemosensory Array: A Disulfide Mapping and Mutagenesis Study

(2013) Andrew M. Natale et al.   BIOCHEMISTRY

The 3.2 Å Resolution Structure of a Receptor:CheA:CheW Signaling Complex Defines Overlapping Binding Sites and Key Residue Interactions within Bacterial Chemosensory Arrays

(2013) Xiaoxiao Li et al.   BIOCHEMISTRY

The mobility of two kinase domains in theEscherichia colichemoreceptor array varies with signalling state

(2013) Ariane Briegel et al.   MOLECULAR MICROBIOLOGY

A phenylalanine rotameric switch for signal-state control in bacterial chemoreceptors

(2013) Davi R. Ortega et al.   Nature Communications

Conformational Coupling between Receptor and Kinase Binding Sites through a Conserved Salt Bridge in a Signaling Complex Scaffold Protein

(2013) Davi R. Ortega et al.   PLoS Computational Biology

Evolution of Two-Component Signal Transduction Systems

(2012) Emily J. Capra et al.   Annual Review of Microbiology

CheA–Receptor Interaction Sites in Bacterial Chemotaxis

(2012) Xiqing Wang et al.   JOURNAL OF MOLECULAR BIOLOGY

Bacterial chemoreceptor arrays are hexagonally packed trimers of receptor dimers networked by rings of kinase and coupling proteins

(2012) A. Briegel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular architecture of chemoreceptor arrays revealed by cryoelectron tomography of Escherichia coli minicells

(2012) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MDAnalysis: A toolkit for the analysis of molecular dynamics simulations

(2011) Naveen Michaud-Agrawal et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

The Receptor–CheW Binding Interface in Bacterial Chemotaxis

(2011) Anh Vu et al.   JOURNAL OF MOLECULAR BIOLOGY

Core unit of chemotaxis signaling complexes

(2011) M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the Ternary Complex Formed by a Chemotaxis Receptor Signaling Domain, the CheA Histidine Kinase, and the Coupling Protein CheW As Determined by Pulsed Dipolar ESR Spectroscopy

(2010) Jaya Bhatnagar et al.   BIOCHEMISTRY

Bacterial chemoreceptors: providing enhanced features to two-component signaling

(2010) Gerald L Hazelbauer et al.   CURRENT OPINION IN MICROBIOLOGY

Spatial organization in bacterial chemotaxis

(2010) Victor Sourjik et al.   EMBO JOURNAL

The Chemoreceptor Dimer Is the Unit of Conformational Coupling and Transmembrane Signaling

(2010) D. N. Amin et al.   JOURNAL OF BACTERIOLOGY

Chemotaxis kinase CheA is activated by three neighbouring chemoreceptor dimers as effectively as by receptor clusters

(2010) Mingshan Li et al.   MOLECULAR MICROBIOLOGY

The Core Signaling Proteins of Bacterial Chemotaxis Assemble To Form an Ultrastable Complex

(2009) Annette H. Erbse et al.   BIOCHEMISTRY

Signal amplification in a lattice of coupled protein kinases

(2009) Jacki P. Goldman et al.   Molecular BioSystems

Universal architecture of bacterial chemoreceptor arrays

(2009) A. Briegel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flexible Fitting of Atomic Structures into Electron Microscopy Maps Using Molecular Dynamics

(2008) Leonardo G. Trabuco et al.   STRUCTURE

Bacterial chemoreceptors: high-performance signaling in networked arrays

(2008) Gerald L. Hazelbauer et al.   TRENDS IN BIOCHEMICAL SCIENCES