Article
Veterinary Sciences
Huseyin Can, Mervenur Guvendi, Ecem Surgec, Ahmet Efe Koseoglu, Sedef Erkunt Alak, Muhammet Karakavuk, Aytul Gul, Mert Doskaya, Adnan Yuksel Guruz, Cemal Un, Aysu Degirmenci Doskaya
Summary: This study genotyped B. henselae samples isolated from stray cats in Turkey for the first time, identifying ST1, ST5, ST9, ST35, and ST36 as well as a new sequence type named ST38 among these B. henselae isolates.
BMC VETERINARY RESEARCH
(2023)
Article
Microbiology
Chunyan Wang, Haoran Zhang, Jiaqi Fu, Meng Wang, Yuhao Cai, Tianyun Ding, Jiezhang Jiang, Jane E. Koehler, Xiaoyun Liu, Congli Yuan
Summary: BepC facilitates internalization of large Bartonella aggregates into host cells by modulating F-actin polymerization, followed by inducing stress fiber formation and cell fragmentation. The interaction between BepC and GEF-H1 leads to the release of GEF-H1 and activation of RhoA, ultimately inducing stress fiber formation.
Article
Microbiology
Wan Zhao, Jinting Yu, Feng Jiang, Wei Wang, Le Kang, Feng Cui
Summary: Maintenance of a balance between viral replication and selective pressure from insect vectors' immune systems is crucial for efficient transmission of insect-borne phytoviruses, with the mechanisms of RNA virus adaptation to insect vectors remaining largely unknown. In this study, researchers found that terminal extensions in the genome of rice stripe virus (RSV) can suppress viral replication in insect vectors by interfering with a key structure, and endogenous insect microRNA can relieve this inhibitory effect. However, RSV infection negatively regulates the expression of this microRNA, highlighting an intricate coordination between viral genome variation and insect microRNAs in controlling RSV replication in planthopper vectors.
Article
Multidisciplinary Sciences
Dillon B. Nye, Nathan A. Tanner
Summary: Recent advances in next generation sequencing technologies have made it possible to read DNA molecules hundreds of kilobases in length. This has motivated the development of DNA amplification methods capable of producing long amplicons. In this study, the researchers investigated strand-displacement amplification reactions using the T7 replisome, a multiprotein complex involved in DNA replication. They utilized Oxford Nanopore long-read sequencing technology to gain insight into the reaction mechanism. The results revealed chimeric DNA reads and a connection between template switching and polymerase exonuclease activity.
Article
Cardiac & Cardiovascular Systems
Tsukasa Ohno, Shunei Saito, Eri Iwata, Sen Ushida, Ryohei Otsuka, Ken Miyahara, Akio Matsuura
Summary: A 75-year-old woman presented with pancytopenia, hepatosplenomegaly, and low-grade fever, and was diagnosed with infective endocarditis caused by Bartonella henselae. She underwent aortic valve replacement surgery and had a smooth postoperative recovery.
INDIAN JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Medicine, General & Internal
Sang Mee Hwang, Hee Won Cho, Tae Yeul Kim, Jeong Su Park, Jongtak Jung, Kyoung-Ho Song, Hyunju Lee, Eu Suk Kim, Hong Bin Kim, Kyoung Un Park
Summary: This study investigated an outbreak of carbapenem-resistant Acinetobacter baumannii (CRAB) in a hospital setting using whole-genome sequencing and various bioinformatics tools. Three clonal lineages were identified among the 11 isolates analyzed, all of which were found to harbor genes associated with multidrug resistance. Different clones were found within the MLST types through whole-genome MLST and whole-genome SNP analyses, with wgSNP showing the highest discriminatory power.
Article
Plant Sciences
Anne Caroline Joly, Shahinez Garcia, Jean-Michel Hily, Sandrine Koechler, Gerard Demangeat, Damien Garcia, Emmanuelle Vigne, Olivier Lemaire, Helene Zuber, Dominique Gagliardi
Summary: Plant viral RNAs can undergo uridylation, which has diverse patterns and potential pro- and antiviral functions. In this study, the global 3' terminal RNA uridylation profiles of various phytoviruses were analyzed, revealing the prevalence of uridylation in viral RNAs. It was found that grapevine fanleaf virus (GFLV) RNAs have a unique monouridylation pattern, which becomes dominant during infection. The uridylation of viral RNAs was found to be independent of known terminal uridylyltransferases (TUTases), but these TUTases can uridylate other viral RNAs. Our findings highlight the importance of uridylation in plant-virus interactions and provide valuable insights into the diverse roles of uridylation.
Article
Ophthalmology
Sunil Bellur, Amir Ali, Nam V. Nguyen, Joshua K. Fernandes, Shilpa Kodati
Summary: This report describes a case of central retinal vein occlusion (CRVO) as the initial sign of ocular Bartonella henselae infection. A 36-year-old male presented with unilateral vision loss and was found to have CRVO with atypical features. Laboratory testing confirmed Bartonella henselae infection and the patient showed a good response to treatment with doxycycline and aflibercept.
JOURNAL OF OPHTHALMIC INFLAMMATION AND INFECTION
(2023)
Article
Microbiology
Preethi Sathanantham, Wenhao Zhao, Guijuan He, Austin Murray, Emma Fenech, Arturo Diaz, Maya Schuldiner, Xiaofeng Wang
Summary: A conserved helix structure was discovered to determine the localization of viral replication complexes (VRCs), which may serve as a potential target for developing broad-spectrum antiviral strategies.
Article
Virology
Mark D. Stenglein
Summary: Virology has mainly focused on pathogenic viruses to humans and other important species, but there is value in studying relatively unknown viruses and hosts. This review highlights the benefits of studying off the beaten track viruses and hosts. It discusses the bias in our understanding of host-virus interactions and the gains made through metagenomic discovery of new viruses. The study suggests that studying viruses in existing and emerging model organisms can push virology forward in useful and unpredictable ways.
ANNUAL REVIEW OF VIROLOGY
(2022)
Article
Ophthalmology
R. U. S. S. E. L. L. N. VAN GELDER
Summary: This article reviews the use of molecular diagnostic techniques in the management of ocular infectious diseases. The advancements in PCR and Next Generation Sequencing have greatly improved the detection and diagnosis of pathogens.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Microbiology
Jee Youn Hwang, Unn Hwa Lee, Min Jin Heo, Min Sun Kim, Ji Min Jeong, So Yeon Kim, Mun Gyeong Kwon, Bo Young Jee, Ki Hong Kim, Chan-Il Park, Jeong Woo Park
Summary: Viral hemorrhagic septicemia virus (VHSV) is a rhabdovirus causing high mortality in cultured flounder, and a study identifies an amino acid substitution in the P protein that enhances its virulence in flounder. This discovery contributes to the understanding of VHSV virulence in flounder and holds potential for vaccine development.
Article
Multidisciplinary Sciences
Megan D. Niner, Carol A. Stepien, Bartolomeo Gorgoglione, Douglas W. Leaman
Summary: This study conducted the largest whole genome sequencing analysis of a highly virulent subgenogroup (-IVb) of Piscine novirhabdovirus, known as VHSV. Results show changes in immunogenicity in cell culture. Different VHSV genogroups and subgenogroups exhibit varying substitution rates, suggesting that VHSV-IVb has undergone continued sequence change and a trend towards lower virulence over its evolutionary history.
Article
Veterinary Sciences
Kamrul Ahmed Khan, Md. Alimul Islam, Abdullah Al Momen Sabuj, Md. Abul Bashar, Md. Saiful Islam, Md. Golzar Hossain, Muhammed Tofazzal Hossain, Sukumar Saha
Summary: This study detected circulating duck plague virus (DPV) in infected ducks from five Haor districts in Bangladesh, revealing a high prevalence of DPV. The isolates were found to be closely related to Chinese DPV isolates, and certain isolates showed genetic variability that may impact protein function and drug sensitivity.
OPEN VETERINARY JOURNAL
(2021)
Review
Genetics & Heredity
Jaya B. Lakshmi, M. L. Avinash Tejasvi, Anulekha Avinash, H. P. Chanchala, Priyanka Talwade, Mohammed Malik Afroz, Archana Pokala, Praveen Kumar Neela, T. K. Shyamilee, Vammi Srisha
Summary: DNA, unique to each individual, is present in most cells in our body, leaving a trail wherever we go, a useful tool for forensic investigators in identification. The use of genetic markers in forensic investigation is described in this review, along with their limitations.
GLOBAL MEDICAL GENETICS
(2021)
Article
Veterinary Sciences
Jamie M. Fink, George E. Moore, Ruth Landau, Ramesh Vemulapalli
JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION
(2015)
Article
Immunology
Neha Dabral, Neeta Jain-Gupta, Mohamed N. Seleem, Nammalwar Sriranganathan, Ramesh Vemulapalli
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2015)
Article
Immunology
Sriveny Dangoudoubiyam, Ramesh Vemulapalli, Momar Ndao, Kevin R. Kazacos
CLINICAL AND VACCINE IMMUNOLOGY
(2011)
Article
Immunology
Neeta Jain-Gupta, Araceli Contreras-Rodriguez, Ramesh Vemulapalli, Sharon G. Witonsky, Stephen M. Boyle, Nammalwar Sriranganathan
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY
(2012)
Article
Biotechnology & Applied Microbiology
A. M. S. Guimaraes, R. F. C. Vieira, R. Poletto, R. Vemulapalli, A. P. Santos, W. de Moraes, Z. S. Cubas, L. C. Santos, J. N. Marchant-Forde, J. Timenetsky, A. W. Biondo, J. B. Messick
JOURNAL OF APPLIED MICROBIOLOGY
(2011)
Article
Pathology
C. Frank, R. Vemulapalli, T. Lin
JOURNAL OF COMPARATIVE PATHOLOGY
(2011)
Article
Multidisciplinary Sciences
Neha Dabral, Martha-Moreno-Lafont, Nammalwar Sriranganathan, Ramesh Vemulapalli
Article
Immunology
Dina Moustafa, Virendra K. Garg, Neeta Jain, Nammalwar Sriranganathan, Ramesh Vemulapalli
Article
Immunology
N. Jain-Gupta, A. Contreras-Rodriguez, G. P. Smith, V. K. Garg, S. G. Witonsky, S. Isloor, R. Vemulapalli, S. M. Boyle, N. Sriranganathan
Article
Veterinary Sciences
Katie M. Boes, Kristina O. Goncarovs, Craig A. Thompson, Lindsay A. Halik, Andrea P. Santos, Ana M. S. Guimaraes, Marybeth Miskovic Feutz, Patricia J. Holman, Ramesh Vemulapalli, Joanne B. Messick
VETERINARY CLINICAL PATHOLOGY
(2012)
Article
Parasitology
Emily Shebish, Ramesh Vemulapalli, Christian Oseto
VETERINARY PARASITOLOGY
(2012)
Article
Immunology
Jianguo Zhu, Charles B. Larson, Megan Ann Ramaker, Kimberly Quandt, Jered M. Wendte, Kimberly P. Ku, Fang Chen, George W. Jourdian, Ramesh Vemulapalli, Gerhardt G. Schurig, Yongqun He
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2011)
Article
Multidisciplinary Sciences
Neha Dabral, Grant N. Burcham, Neeta Jain-Gupta, Nammalwar Sriranganathan, Ramesh Vemulapalli
Article
Multidisciplinary Sciences
Rishi Drolia, Mary Anne Roshni Amalaradjou, Valerie Ryan, Shivendra Tenguria, Dongqi Liu, Xingjian Bai, Luping Xu, Atul K. Singh, Abigail D. Cox, Victor Bernal-Crespo, James A. Schaber, Bruce M. Applegate, Ramesh Vemulapalli, Arun K. Bhunia
NATURE COMMUNICATIONS
(2020)
Article
Multidisciplinary Sciences
Miryan Margot Sanchez-Jimenez, Juan Jacobo de la Cuesta Zuluaga, Gisela Maria Garcia-Montoya, Neha Dabral, Juan Fernando Alzate, Ramesh Vemulapalli, Martha Olivera-Angel