Article
Parasitology
Katharine Costa dos Santos, Eric Tielemans, Andre Antonio Cutolo, Paula Elisa Brandao Guedes, Tatiani Vitor Harvey, Jamille Bispo de Carvalho Teixeira, Rebeca Costa Vitor, Anaia da Paixao Seva, Adan William de Melo Navarro, Ana Carolina Ribeiro Lima, Karin Denise Botteon, Thammy Vieira Bittar, George Rego Albuquerque, Fernando de Almeida Borges, Frederic Beugnet, Renata Santiago Alberto Carlos
Summary: This study assessed the efficacy of NexGard Spectra (R) against canine tungiasis and proved its high effectiveness. In addition to benefiting the health and welfare of treated dogs, the use of this product may have a one-health benefit on human cases by controlling the main reservoir of sand fleas.
PARASITES & VECTORS
(2023)
Article
Parasitology
Andrei Daniel Mihalca, Georgiana Deak, Luciana Catalina Panait, Stefan Rabei, Frederic Beugnet
Summary: This study evaluated the efficacy of afoxolaner, an isoxazoline class compound, in treating natural infestation of chewing lice in domestic dogs. The results showed that afoxolaner demonstrated 100% curative efficacy, suggesting it as a feasible treatment option for chewing lice in dogs.
PARASITES & VECTORS
(2022)
Article
Parasitology
Conrad A. Matthee, Anandi Bierman, Boris R. Krasnov, Sonja Matthee, Luther van der Mescht
Summary: This study conducted a metagenetic analysis of flea samples collected from different sampling sites in South Africa, and found that the bacterial diversity of the parasites is influenced by host species and environmental factors. Differences in microbiome compositions were observed between different flea species and across geographic sampling sites, with temperature and humidity identified as potentially important environmental factors.
Article
Veterinary Sciences
Elizabeth Mitchell, Eric Tielemans, John W. McCall, Christine Baker, Elizabeth Martin, Justin Frost, Stephen Yoon, Becky Fankhauser
Summary: The efficacy of an oral endectoparasiticide product combining moxidectin, afoxolaner, and pyrantel pamoate was evaluated for the prevention of heartworm disease in dogs. Laboratory and field studies showed that monthly administration of the product for at least six doses is effective at preventing dirofilariosis.
RESEARCH IN VETERINARY SCIENCE
(2023)
Article
Parasitology
Eric Tielemans, Prescillia Buellet, David Young, Alta Viljoen, Julian Liebenberg, Joe Prullage
Summary: NexGard(R) Combo is a novel topical endectoparasiticide formulation for cats, containing esafoxolaner, a purified enantiomer of afoxolaner with insecticidal and acaricidal properties, combined with eprinomectin and praziquantel. Experimental studies have shown that this formulation is effective against adult and immature stages of Ctenocephalides felis fleas.
Article
Parasitology
Rafael Chiummo, Eva Zschiesche, Balazs Capari, Robert Farkas, Mathieu Chiquet, Dhimiter Rapti, Rezart Postoli, Alain Audry, Michael Leschnik
Summary: This study demonstrated that the use of fluralaner chewable tablets effectively prevents the transmission of Babesia canis in dogs under natural conditions, with a 100% efficacy rate.
PARASITES & VECTORS
(2023)
Article
Parasitology
Angela Di Cesare, Simone Morelli, Giulia Morganti, Giulia Simonato, Fabrizia Veronesi, Mariasole Colombo, Michele Berlanda, Wilfried Lebon, Matilde Gallo, Frederic Beugnet, Donato Traversa
Summary: The study demonstrated that NEXGARD SPECTRA(R) was safe and highly effective in reducing Capillaria aerophila and Capillaria boehmi eggs in dogs after one treatment, with complete reduction of egg output and recovery from respiratory signs after the second administration.
PARASITES & VECTORS
(2021)
Article
Parasitology
Tandy Paarlberg, Daniela Karadzovska, Rainer Helbig
Summary: Lotilaner showed significant efficacy in treating flea infestations and reducing flea egg production in cats following a single oral administration, virtually eliminating all adult fleas and reducing the number of eggs produced.
PARASITES & VECTORS
(2021)
Article
Pharmacology & Pharmacy
Marlene Drag, Eric Tielemans, Elizabeth Mitchell
Summary: The safety of oral Afoxolaner, alone or in combination with milbemycin oxime, was investigated in homozygous MDR1-deficient collie dogs, and no significant adverse reactions were observed.
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS
(2022)
Article
Pharmacology & Pharmacy
Sukannika Tubtimsri, Yotsanan Weerapol
Summary: A self-microemulsifying gel with improved solubility and absorption of Itraconazole (ICZ) was prepared for oral mucosa. The gel formulation with a ratio of 15:50:35 showed good elasticity and release rate. It can be used as a novel carrier for the treatment of oral candidiasis.
Article
Agriculture, Dairy & Animal Science
Xenabeth A. Lazaro, John M. Winter, Jonathan K. Fernand, David J. Cox, Nicole R. Dorey
Summary: This study aimed to compare the effectiveness of food and leisure stimuli as reinforcers for domestic dogs. The results showed that domestic dogs generally preferred food over leisure items and that food was a more effective reinforcer for dog behavior. These findings are important for dog owners and trainers, indicating that using food as a reinforcer may lead to better training results.
Article
Immunology
Katharina Bobe, Steffen Ortmann, Christian Kaiser, David Perez-Bravo, Joern Gethmann, Jeannette Kliemt, Sophia Koerner, Tobias Theuss, Thomas Lindner, Conrad Freuling, Thomas Mueller, Ad Vos
Summary: The third-generation oral rabies virus vaccine strain, SPBN GASGAS, has been proven to be effective in protecting domestic dogs against rabies. It meets the international standards and can be used for mass dog vaccination.
Article
Agriculture, Dairy & Animal Science
Linda Behrendorff, Rachel King, Benjamin L. Allen
Summary: This study collected and analyzed reports of human-dingo interactions on K'gari Island since 1990. The results showed that food influences dingo behavior and that nonlethal management actions can reduce food-related interactions. Further innovations are needed to reduce serious incidents involving dingoes and humans.
Article
Pharmacology & Pharmacy
Gabriela Carmelinda Martins dos Santos, Fabio Barbour Scott, Diefrey Ribeiro Campos, Viviane de Sousa Magalhaes, Debora Azevedo Borges, Fernando Rocha Miranda, Melina Cardilo Campos Alves, Geraldo Augusto Pereira, Leandra Oliveira Moreira, Emily Andressa Santos Lima, Marisa Beatriz da Silva Rocha, Yara Peluso Cid
Summary: Fipronil, an ectoparasiticide used in veterinary medicine, has shown promising efficacy through oral administration in dogs. Plasma concentration curves indicate rapid absorption and metabolism of FIP, with slow elimination. Doses of 4 mg/kg and 6 mg/kg provided 100% and 95% efficacy against fleas and ticks within 48 hours, respectively.
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS
(2022)
Article
Veterinary Sciences
Hyung-Kyu Chae, Ye-In Oh, Sumin Park, Ju-Hyun An, Kyoungwon Seo, Kyuyong Kang, Seung-nam Chu, Hwa-Young Youn
Summary: This study retrospectively evaluated the efficacy and safety of oral paclitaxel in dogs with various cancers. The results showed good response rates in certain cancer types and minimal adverse events. Therefore, oral paclitaxel could be a viable option for managing cancer in dogs.
VETERINARY MEDICINE AND SCIENCE
(2022)