Journal
VETERINARY PARASITOLOGY
Volume 160, Issue 3-4, Pages 267-271Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.vetpar.2008.11.010
Keywords
Anthelmintic resistance; In vitro detection; Haemonchus contortus; Benzimidazole; Ivermectin
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Funding
- EU [FOOD-CT-2005-022851]
- Slovak Research and Development Agency [RPEU-009-06]
- VEGA
- Slovak Academy of Sciences [2/7189/27]
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Larval development (LDT) and micro-agar larval development tests (MALDT) were used to compare the reliability and sensitivity of two methods for detecting anthelmintic resistance in Haemonchus contortus. The tests were conducted using three resistant and four susceptible isolates of H. contortus. Both versions of the tests provided comparable results with regard to the characterization of benzimidazole and levamisole susceptibility but neither test was sufficiently sensitive to discrimination between an ivermectin (IVM) susceptible and an IVM resistant isolate. Each test has its own merits with the LDT having the advantage of being less time-consuming. (C) 2008 Elsevier B.V. All rights reserved.
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