Journal
VETERINARY MICROBIOLOGY
Volume 145, Issue 3-4, Pages 230-244Publisher
ELSEVIER
DOI: 10.1016/j.vetmic.2010.04.008
Keywords
Swine influenza virus; H3N2; Phylogenetic analysis
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Funding
- BlOTEC, Thailand [BT-B01-MG-11-4916]
- Center of Excellence on Agricultural Biotechnology, Postgraduate Education and Research Development Office, Commission on Higher Education, Ministry of Education
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H3N2 swine influenza viruses (SIV) were first detected in Asia shortly after the 1968 pandemic emerged in humans. Subsequently, human H3N2 viruses have sporadically reappeared in swine. In Thailand, a human-like H3N2 Sly was reported in 1978 although the genetic sequence of this virus is unknown. In this study, we undertook cross sectional syndromic surveillance in pigs in four provinces in Thailand. Seven genetically similar H3N2 viruses were isolated. A representative, A/SW/Thailand/KU5.1/04, was fully sequenced and shown to contain genes from human-like influenza viruses and North American and European Sly. The results restate that transmission of influenza A virus among human and swine populations is common and that genes from both American and Eurasian SIV lineages cocirculate in Thailand. (C) 2010 Elsevier B.V. All rights reserved.
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