Signaling regulating inner ear development: Cell fate determination, patterning, morphogenesis, and defects

FGFR1-Frs2/3 Signalling Maintains Sensory Progenitors during Inner Ear Hair Cell Formation

(2014) Kazuya Ono et al.   PLoS Genetics

Mechanism of cell fate choice between neural and mesodermal development during early embryogenesis

(2013) Tatsuya Takemoto   CONGENITAL ANOMALIES

Divergent roles for Wnt/ -catenin signaling in epithelial maintenance and breakdown during semicircular canal formation

(2013) S. Rakowiecki et al.   DEVELOPMENT

A Molecular Blueprint at the Apical Surface Establishes Planar Asymmetry in Cochlear Hair Cells

(2013) Basile Tarchini et al.   DEVELOPMENTAL CELL

Genetic rescue of Muenke syndrome model hearing loss reveals prolonged FGF-dependent plasticity in cochlear supporting cell fates

(2013) S. L. Mansour et al.   GENES & DEVELOPMENT

Progression of Neurogenesis in the Inner Ear Requires Inhibition of Sox2 Transcription by Neurogenin1 and Neurod1

(2013) L. Evsen et al.   JOURNAL OF NEUROSCIENCE

Early Development of the Vertebrate Inner Ear

(2012) MARTA MagariÑos et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Sonic hedgehog signaling coordinates the proliferation and differentiation of neural stem/progenitor cells by regulating cell cycle kinetics during development of the neocortex

(2012) Munekazu Komada   CONGENITAL ANOMALIES

Delta-like 1 and lateral inhibition during hair cell formation in the chicken inner ear: evidence against cis-inhibition

(2012) E. Chrysostomou et al.   DEVELOPMENT

Patterning and cell fate in the inner ear: a case for Notch in the chicken embryo

(2012) Joana Neves et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Mutual repression between Gbx2 and Otx2 in sensory placodes reveals a general mechanism for ectodermal patterning

(2012) Ben Steventon et al.   DEVELOPMENTAL BIOLOGY

Fgf signaling regulates development and transdifferentiation of hair cells and supporting cells in the basilar papilla

(2012) Bonnie E. Jacques et al.   HEARING RESEARCH

High prevalence of inner-ear and/or internal auditory canal malformations in children with unilateral sensorineural hearing loss

(2012) Sawako Masuda et al.   INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY

Notch Prosensory Effects in the Mammalian Cochlea Are Partially Mediated by Fgf20

(2012) V. Munnamalai et al.   JOURNAL OF NEUROSCIENCE

The Prosensory Function of Sox2 in the Chicken Inner Ear Relies on the Direct Regulation of Atoh1

(2012) Joana Neves et al.   PLoS One

Differentiation of the Lateral Compartment of the Cochlea Requires a Temporally Restricted FGF20 Signal

(2012) Sung-Ho Huh et al.   PLOS BIOLOGY

Jagged 1 regulates the restriction of Sox2 expression in the developing chicken inner ear: a mechanism for sensory organ specification

(2011) J. Neves et al.   DEVELOPMENT

Shaping sound in space: the regulation of inner ear patterning

(2011) A. K. Groves et al.   DEVELOPMENT

Dissecting the molecular basis of organ of Corti development: Where are we now?

(2011) Bernd Fritzsch et al.   HEARING RESEARCH

Notch Signaling Alters Sensory or Neuronal Cell Fate Specification of Inner Ear Stem Cells

(2011) S.-J. Jeon et al.   JOURNAL OF NEUROSCIENCE

From shared lineage to distinct functions: the development of the inner ear and epibranchial placodes

(2010) R. K. Ladher et al.   DEVELOPMENT

Independent regulation of Sox3 and Lmx1b by FGF and BMP signaling influences the neurogenic and non-neurogenic domains in the chick otic placode

(2010) G. Abelló et al.   DEVELOPMENTAL BIOLOGY

FGF signaling regulates otic placode induction and refinement by controlling both ectodermal target genes and hindbrain Wnt8a

(2010) Lisa D. Urness et al.   DEVELOPMENTAL BIOLOGY

Conditional deletion of Atoh1 using Pax2-Cre results in viable mice without differentiated cochlear hair cells that have lost most of the organ of Corti

(2010) Ning Pan et al.   HEARING RESEARCH

BMP Signaling Is Necessary for Patterning the Sensory and Nonsensory Regions of the Developing Mammalian Cochlea

(2010) T. Ohyama et al.   JOURNAL OF NEUROSCIENCE

Congenital malformations of the inner ear: A classification based on embryogenesis

(2010) Robert K Jackler et al.   LARYNGOSCOPE

Transient retinoic acid signaling confers anterior-posterior polarity to the inner ear

(2010) J. Bok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specification of cell fate in the mammalian cochlea

(2009) Elizabeth C. Driver et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Myosin II regulates extension, growth and patterning in the mammalian cochlear duct

(2009) N. Yamamoto et al.   DEVELOPMENT

Additional temporal bone findings on computed tomography imaging in branchio-oto-renal syndrome

(2009) Emrah Senel et al.   LARYNGOSCOPE

Progressive restriction of otic fate: the role of FGF and Wnt in resolving inner ear potential

(2008) S. Freter et al.   DEVELOPMENT

Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea

(2008) Toshinori Hayashi et al.   DEVELOPMENTAL BIOLOGY

Hearing loss in a mouse model of Muenke syndrome

(2008) Suzanne L. Mansour et al.   HUMAN MOLECULAR GENETICS

Fgf20 Is Required for Sensory Epithelial Specification in the Developing Cochlea

(2008) T. Hayashi et al.   JOURNAL OF NEUROSCIENCE

Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea

(2008) A. Dabdoub et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial-Mesenchymal Transition as a Possible Mechanism of Semicircular Canal Morphogenesis in Chick Inner Ear

(2008) Yuriko Kobayashi et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Bmp4 Is Essential for the Formation of the Vestibular Apparatus that Detects Angular Head Movements

(2008) Weise Chang et al.   PLoS Genetics

Murine Dishevelled 3 Functions in Redundant Pathways with Dishevelled 1 and 2 in Normal Cardiac Outflow Tract, Cochlea, and Neural Tube Development

(2008) S. Leah Etheridge et al.   PLoS Genetics