Article
Allergy
Jojo B. Dietz, Torkil Menne, Harald W. Meyer, Sven Viskum, Mari-Ann Flyvholm, Ulrik Ahrensboll-Friis, Swen M. John, Jeanne D. Johansen
Summary: This study found a high prevalence of previously diagnosed AD among young workers with recognized OCD, and AD significantly impacts the severity and long-term consequences of OCD.
CONTACT DERMATITIS
(2023)
Article
Veterinary Sciences
Jennifer L. Kelley, Naomi K. Hoyer, Sangeeta Rao, Jennifer E. Rawlinson
Summary: This study aimed to identify prognostic indicators for feline craniofacial trauma patients and determine their association with negative and positive outcomes. Factors such as patient sex, trauma etiology, and initial presentation scores were found to be associated with prognosis. These prognostic indicators can guide clinical decision making.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Dermatology
Amir Horev, Guy Shalom, Adi Y. Weintraub, Tamar Freud, Arnon D. Cohen
Summary: A retrospective cohort study found that AD patients have a higher risk of infertility compared to a control group, and this association was observed in both different age groups and severity levels of AD.
Article
Dermatology
Hadley Johnson, Marcella R. Aquino, Alan Snyder, Reid W. Collis, Katlein Franca, Alina Goldenberg, Jennifer Y. Sui, Dawn Z. Eichenfield, Brittany J. Kozy, Jennifer K. Chen, Chelsea Shope, Ari M. Goldminz, JiaDe Yu
Summary: Children with atopic dermatitis are more likely to have allergic contact dermatitis and should undergo evaluation and patch testing for allergic contact dermatitis.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2023)
Letter
Dermatology
Nicole S. Stefanko, Victor L. Quan, Raj Chovatiya
Summary: This study investigates the diagnostic delay in an autoimmune skin disease. The use of C3d and C4d immunohistochemistry is found to be a valuable tool in the diagnosis of inflammatory skin diseases.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2023)
Article
Medicine, General & Internal
Jen A. Barak Levitt, Sima Alemi, Ayelet Ollech, Shiran Reiss-Huss, Mohammad Sah, Yael Renert-Yuval, Rivka Friedland, Shoshana Greenberger, Eran Cohen Barak
Summary: This study investigated the efficacy and safety of methotrexate treatment in 28 infants and toddlers under the age of 4 with atopic dermatitis. After treatment, 50% of patients showed significant improvement at 12 weeks, and 21.4% achieved remission at 24 weeks. Although 57.1% of patients experienced adverse events, only two patients discontinued the treatment due to these events.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Dermatology
C. Droitcourt, I. Vittrup, A. Dupuy, A. Egeberg, J. P. Thyssen
Summary: Children with hospital-managed atopic dermatitis are at increased risk of systemic infections that require hospitalization, including respiratory, urinary tract, musculoskeletal, and gastrointestinal infections. The absolute risk is generally low.
BRITISH JOURNAL OF DERMATOLOGY
(2021)
Review
Dermatology
Sabrina Khan, Ruth Asher, William Perkins, Rubeta N. Matin
Summary: This study retrospectively reviewed patient records of cutaneous leiomyosarcoma (LMS) and proposed margin recommendations for clinical and histological excision. The study found that for dermal LMS, a clinical margin of 5-10 mm was suggested, while for subcutaneous LMS, a clinical margin of 15-20 mm was recommended.
CLINICAL AND EXPERIMENTAL DERMATOLOGY
(2023)
Article
Dermatology
T. Torres, M. J. Paiva-Lopes, M. Goncalo, C. Claro, M. Oliveira, J. Gomes, A. P. Vieira, P. Amoedo, M. Alpalhao, M. Nogueira, F. Santiago, M. Henrique, C. Amaro, T. Esteves, J. Alves, D. Cerejeira, P. Mendes-Bastos, M. Pestana, L. Ramos, J. Rocha, R. Carvalho, L. Teixeira, M. Selores, A. Mota, P. Filipe
Summary: Dupilumab, an IL-4 and IL-13 inhibitor, has been shown to be an effective and safe therapeutic option for the treatment of atopic dermatitis (AD). This study provides real-world data demonstrating its efficacy and safety in a nationwide cohort of AD patients.
JOURNAL OF DERMATOLOGICAL TREATMENT
(2022)
Article
Dermatology
Jordane Barbe, Claire Poreaux, Thomas Remen, Amelie Schoeffler, Veronique Cloche, Jean-Luc Schmutz, Gabriela Escobar, Anne-Claire Busztejn
Summary: The study found a prevalence of 36% of ocular disease in AD patients treated with dupilumab, with severe allergic conjunctivitis and blepharitis being more common. Some patients had to permanently discontinue therapy, highlighting the importance of consulting with an ophthalmologist before starting dupilumab treatment.
INTERNATIONAL JOURNAL OF DERMATOLOGY
(2021)
Article
Dermatology
Evelien E. M. Fennis, Catharina M. M. Damme, Yvette M. Schlotter, Jacqueline D. Sinke, Mieke H. G. Leistra, Richard T. Bartels, Femke Broere
Summary: This study retrospectively examined the efficacy of subcutaneous allergen-specific immunotherapy (ASIT) in atopic dogs and found that approximately 59.9% of dogs showed clinical improvement of at least 50% after ASIT. Regular re-examinations and avoidance of systemic glucocorticoid use during the first 9 months of ASIT were associated with better treatment outcomes.
VETERINARY DERMATOLOGY
(2022)
Article
Dermatology
Maddalena Napolitano, Gabriella Fabbrocini, Cataldo Patruno
Summary: Dupilumab, a monoclonal antibody inhibiting IL-4 and IL-13, is approved for the treatment of moderate to severe atopic dermatitis in children aged >= 6 years, adolescents, and adults. Both clinical trials and real-life data demonstrate its efficacy and safety, but some cutaneous adverse events have been observed during real-world experiences.
JOURNAL OF DERMATOLOGY
(2023)
Article
Medicine, General & Internal
Dongxia Ma, Yin Wang, Nan Huang, Wenjing Li, Hao Chen, Yaqi Yang, Rongfei Zhu
Summary: This study conducted a retrospective cross-sectional survey on patients with moderate-to-severe atopic dermatitis (AD), and found that the incidence and severity of COVID-19 were lower in patients treated with dupilumab. The treatment did not prolong the duration of COVID-19. Therefore, AD patients can continue their dupilumab treatment during the COVID-19 pandemic.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Pediatrics
Li Li, Dong-Ji-Hui Zhao, Tao-Yue Yao, Yong-Hua Xiang, Hong Liu, Qiu-Hong Ma, Ke Jin, Si-Ping He
Summary: Congenital pyriform sinus fistula in neonates often presents on the left side of the neck, with CT showing higher diagnostic accuracy and detection rates compared to US. As age increases, the likelihood of certain features such as thickening of the cyst wall also increases.
FRONTIERS IN PEDIATRICS
(2021)
Article
Dermatology
Joel G. DeKoven, Benjamin M. DeKoven, Erin M. Warshaw, C. G. T. Mathias, James S. Taylor, Denis Sasseville, Donald Belsito, Joseph F. Fowler, Melanie D. Pratt, Kathryn A. Zug, Howard Maibach, Vincent A. DeLeo, Jonathan Silverberg, Amber R. Atwater, Margo J. Reeder, D. Linn Holness
Summary: This study provides an overview of occupational skin disease (OSD) and analyzes the cases of occupational allergic contact dermatitis (ACD) in North American patients undergoing patch testing. The study identified common occupational allergens, exposure sources, and occupations/industries at risk, which can help clinicians evaluate and manage patients with occupational contact dermatitis.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2022)