The stratum corneum: the rampart of the mammalian body

Altered stratum corneum barrier and enhanced percutaneous immune responses in filaggrin-null mice

(2012) Hiroshi Kawasaki et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans

(2012) Anaïs Grall et al.   NATURE GENETICS

Atopic dermatitis in dogs is associated with a high heterogeneity in the distribution of protein-bound lipids within the stratum corneum

(2011) Iuliana Popa et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Genome-wide linkage study of atopic dermatitis in West Highland White Terriers

(2011) Cary A Salzmann et al.   BMC GENETICS

Alteration of stratum corneum ceramide profiles in spontaneous canine model of atopic dermatitis

(2011) Ji-Seon Yoon et al.   EXPERIMENTAL DERMATOLOGY

Lamellar Lipid Organization and Ceramide Composition in the Stratum Corneum of Patients with Atopic Eczema

(2011) Michelle Janssens et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Caspase-14 Is Required for Filaggrin Degradation to Natural Moisturizing Factors in the Skin

(2011) Esther Hoste et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Involvement of corneodesmosome degradation and lamellar granule transportation in the desquamation process

(2011) Akemi Ishida-Yamamoto et al.   Medical Molecular Morphology

Flaky Tail Mouse Denotes Human Atopic Dermatitis in the Steady State and by Topical Application with Dermatophagoides pteronyssinus Extract

(2010) Catharina Sagita Moniaga et al.   AMERICAN JOURNAL OF PATHOLOGY

Analysis of free and protein-bound ceramides by tape stripping of stratum corneum from dogs

(2010) Iuliana Popa et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

The association between null mutations in the filaggrin gene and contact sensitization to nickel and other chemicals in the general population

(2010) J.P. Thyssen et al.   BRITISH JOURNAL OF DERMATOLOGY

Filaggrin null mutations and association with contact allergy and allergic contact dermatitis: results from a tertiary dermatology clinic

(2010) Berit Christina Carlsen et al.   CONTACT DERMATITIS

Missing C-terminal filaggrin expression, NFkappaB activation and hyperproliferation identify the dog as a putative model to study epidermal dysfunction in atopic dermatitis

(2010) Ludovic Chervet et al.   EXPERIMENTAL DERMATOLOGY

ABCA12 dysfunction causes a disorder in glucosylceramide accumulation during keratinocyte differentiation

(2010) Susumu Mitsutake et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Changes in the Ceramide Profile of Atopic Dermatitis Patients

(2010) Junko Ishikawa et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Decreased Concentration and Enhanced Metabolism of Sphingosine-1-Phosphate in Lesional Skin of Dogs with Atopic Dermatitis: Disturbed Sphingosine-1-Phosphate Homeostasis in Atopic Dermatitis

(2010) Wolfgang Bäumer et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Despite identifying some shared gene associations with human atopic dermatitis the use of multiple dog breeds from various locations limits detection of gene associations in canine atopic dermatitis

(2010) Shona H. Wood et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Mutations in the Fatty Acid Transport Protein 4 Gene Cause the Ichthyosis Prematurity Syndrome

(2009) Joakim Klar et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Haplotype sharing excludes canine orthologousFilaggrinlocus in atopy in West Highland White Terriers

(2009) J. Barros Roque et al.   ANIMAL GENETICS

Ceramide biosynthesis in keratinocyte and its role in skin function

(2009) Yukiko Mizutani et al.   BIOCHIMIE

Increased stratum corneum serine protease activity in acute eczematous atopic skin

(2009) R. Voegeli et al.   BRITISH JOURNAL OF DERMATOLOGY

FLGmutation p.Lys4021X in the C-terminal imperfect filaggrin repeat in Japanese patients with atopic eczema

(2009) I. Nemoto-Hasebe et al.   BRITISH JOURNAL OF DERMATOLOGY

Transglutaminase 1-deficient recessive lamellar ichthyosis associated with a LINE-1 insertion in Jack Russell terrier dogs

(2009) K.M. Credille et al.   BRITISH JOURNAL OF DERMATOLOGY

Functional Roles of Human Kallikrein-related Peptidases

(2009) Georgia Sotiropoulou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Filaggrin in the frontline: role in skin barrier function and disease

(2009) A. Sandilands et al.   JOURNAL OF CELL SCIENCE

Gene expression in canine atopic dermatitis and correlation with clinical severity scores

(2009) Shona H. Wood et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

A possible mechanism underlying the ceramide deficiency in atopic dermatitis: Expression of a deacylase enzyme that cleaves the N-acyl linkage of sphingomyelin and glucosylceramide

(2009) Genji Imokawa   JOURNAL OF DERMATOLOGICAL SCIENCE

Kallikrein 5 induces atopic dermatitis–like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome

(2009) Anaïs Briot et al.   JOURNAL OF EXPERIMENTAL MEDICINE

External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers

(2009) Akiharu Kubo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Comprehensive quantification of ceramide species in human stratum corneum

(2009) Yoshinori Masukawa et al.   JOURNAL OF LIPID RESEARCH

A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming

(2009) Padraic G Fallon et al.   NATURE GENETICS

Immunohistochemical evaluation of filaggrin polyclonal antibody in atopic and normal beagles

(2009) Rosanna Marsella et al.   VETERINARY DERMATOLOGY

Increased transepidermal water loss and decreased ceramide content in lesional and non-lesional skin of dogs with atopic dermatitis

(2009) Kenichiro Shimada et al.   VETERINARY DERMATOLOGY

Characterization and quantification of ceramides in the nonlesional skin of canine patients with atopic dermatitis compared with controls

(2009) Lisa V. Reiter et al.   VETERINARY DERMATOLOGY

Transmission electron microscopy studies in an experimental model of canine atopic dermatitis

(2009) Rosanna Marsella et al.   VETERINARY DERMATOLOGY

Chanarin–Dorfman syndrome caused by a novel splice site mutation in ABHD5

(2008) S. Badeloe et al.   BRITISH JOURNAL OF DERMATOLOGY

Kallikrein-related peptidases

(2008) Å. Lundwall et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Lipids and skin barrier function – a clinical perspective

(2008) Jakob Mutanu Jungersted et al.   CONTACT DERMATITIS

The skin: an indispensable barrier

(2008) Ehrhardt Proksch et al.   EXPERIMENTAL DERMATOLOGY

Harlequin ichthyosis model mouse reveals alveolar collapse and severe fetal skin barrier defects

(2008) T. Yanagi et al.   HUMAN MOLECULAR GENETICS

Effects of a Topically Applied Preparation of Epidermal Lipids on the Stratum Corneum Barrier of Atopic Dogs

(2008) A. Piekutowska et al.   JOURNAL OF COMPARATIVE PATHOLOGY

Omega-O-acylceramide, a lipid essential for mammalian survival

(2008) Yoshikazu Uchida et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Highly effective SNP-based association mapping and management of recessive defects in livestock

(2008) Carole Charlier et al.   NATURE GENETICS

Loss-of-Function Mutations in the Filaggrin Gene and Allergic Contact Sensitization to Nickel

(2007) Natalija Novak et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY