Review
Cell Biology
Niloofar Khoshdel-Rad, Ensieh Zahmatkesh, Polina Bikmulina, Maria Peshkova, Nastasia Kosheleva, Evgeny A. Bezrukov, Roman B. Sukhanov, Anna Solovieva, Anastasia Shpichka, Peter Timashev, Massoud Vosough
Summary: The lack of an appropriate platform for understanding the molecular basis of hepatitis viruses and reliable models for identifying new therapeutic agents are major obstacles in launching efficient clinical protocols for viral hepatitis. Traditional models have proven ineffective in representing viral infections in a laboratory setting, highlighting the need for new research models. Cell-based and animal models each have their strengths and weaknesses, with important findings retrieved from both types of models.
Review
Biochemistry & Molecular Biology
Jafar Rezaie, Cynthia Aslan, Mahdi Ahmadi, Naime Majidi Zolbanin, Fatah Kashanchi, Reza Jafari
Summary: Eukaryotic cells produce extracellular vesicles (EVs) that mediate intercellular communication and are utilized by viruses like HIV-1 and HTLV-1 for spreading and infection. Exosomes from virus-infected cells have the potential to be used for vaccine development and early diagnosis of viral infections. Ongoing research on exosomes shed from virus-infected cells may provide insights into the mechanisms of pathogenesis associated with retroviruses.
CELL AND BIOSCIENCE
(2021)
Review
Medicine, General & Internal
Mehdi Borhani, Saeid Fathi, Majid Fasihi Harandi, Sami Simsek, Haroon Ahmed, Xiaoxia Wu, Mingyuan Liu
Summary: This study provides a comprehensive review of Trichinella sp. infection in humans and animals in Iran and Turkey, as well as measures for prevention and control. The research found two cases of human trichinellosis caused by the consumption of wild boar meat in northern Iran. It was also observed that golden jackals in Iran and both domesticated and wild pigs and gray wolves in Turkey are frequently infected. However, data on the distribution of Trichinella taxa in Turkey are still fragmentary.
FRONTIERS IN MEDICINE
(2023)
Review
Biotechnology & Applied Microbiology
S. Gnat, D. Lagowski, A. Nowakiewicz, M. Dylag
Summary: This paper discusses the global status of infectious diseases, focusing on the increasing trend of opportunistic fungal infections and the characteristics of various pathogens. It also introduces the etiology, epidemiology, and symptoms of fungal infections.
JOURNAL OF APPLIED MICROBIOLOGY
(2021)
Review
Veterinary Sciences
Ralf S. Mueller, Katrin Hartmann
Summary: IFNs are important cytokines in the immune response, with recombinant canine IFN-gamma and feline IFN-omega showing efficacy in treating certain diseases in dogs and cats. More large randomized controlled trials are needed to determine their efficacy for other indications.
VETERINARY JOURNAL
(2021)
Article
Neurosciences
Jaakko O. Nieminen, Alexey S. Pospelov, Lari M. Koponen, Pauliina Yrjola, Anastasia Shulga, Stanislav Khirug, Claudio Rivera
Summary: This study developed an experimental set-up for transcranial magnetic stimulation on rodents, overcoming technical difficulties caused by their small head size. The upside-down placement allowed easy navigation of the stimulation, and consistent motor evoked potentials were obtained.
FRONTIERS IN NEUROSCIENCE
(2022)
Review
Veterinary Sciences
Soren R. Boysen, Kris Gommeren
Summary: Intravenous fluids are crucial in shock management, but evidence-based guidelines are lacking in clinical settings. Care must be taken to avoid both under and overhydration, and assessing a patient's volume status and fluid responsiveness, as well as monitoring their response to fluid administration, is essential.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Review
Veterinary Sciences
Chiara Di Franco, Flavia Evangelista, Angela Briganti
Summary: Dexmedetomidine is a versatile drug with various uses, including sedation, analgesia, and as an adjuvant during locoregional anesthesia. Recent studies have also demonstrated its potential neuroprotective, cardioprotective, and vasculoprotective effects, making it valuable in critical care medicine. Dexmedetomidine is ready to face new challenges and continue expanding its applications.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Review
Microbiology
Onur Ceylan, Xuenan Xuan, Ferda Sevinc
Summary: Ticks in Turkey pose a significant challenge to animal production due to the endemic parasitic diseases they carry, including theileriosis, babesiosis, hepatozoonosis, cytauxzoonosis, anaplasmosis, and ehrlichiosis. These diseases have a major impact on the economy and animal health, especially for ruminants, and are controlled primarily through treatment and tick control measures.
Review
Biotechnology & Applied Microbiology
Xue-feng Shi, Bin Ji, Yanyan Kong, Yihui Guan, Ruiqing Ni
Summary: Optoacoustic imaging has versatile applications in biomedical research, visualizing disease pathophysiology and monitoring treatment effects in animal models, as well as in clinical settings. Multimodal imaging provides insights into the complex disease mechanisms with different molecular, structural, and functional readouts in vivo. Rapid development in molecular imaging contrast agents employing a multimodal imaging strategy for pathological targets involved in brain diseases is ongoing.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Biology
Kevin S. Chen, Rui Wu, Marc H. Gershow, Andrew M. Leifer
Summary: Olfactory navigation plays a crucial role in the survival of animals and is observed across species. This study presents a method to control and measure airborne odor concentration in an arena compatible with an agar substrate, allowing continuous monitoring of odor profile while imaging animal behavior. The researchers successfully measured the odor concentration experienced by C. elegans and D. melanogaster larvae populations as they navigate spatial odor landscapes.
Article
Biology
Andre Gustavo Alves Holanda, Danila Evem Alves Cortez, Genilson Fernandes de Queiroz, Julia Maria Matera
Summary: Medical thermography is an imaging test used to monitor skin surface temperature. It has made significant advances since the 2000s with modernization of equipment. Thermography has been widely studied as a screening tool for skin and breast cancer in humans, and has shown promise in veterinary medicine for various tumor types in cats and dogs. This review discusses the fundamentals, monitoring conditions, and future perspectives of using thermography as a diagnostic tool for cancer in veterinary medicine.
JOURNAL OF THERMAL BIOLOGY
(2023)
Article
Infectious Diseases
Isaac Nunez, Brenda Crabtree-Ramirez, Bryan E. Shepherd, Timothy R. Sterling, Pedro Cahn, Valdilea G. Veloso, Claudia P. Cortes, Denis Padgett, Eduardo Gotuzzo, Juan Sierra-Madero, Catherine C. McGowan, Anna K. Person, Yanink Caro-Vega
Summary: This study aims to describe the incidence, clinical characteristics, and risk factors of late-onset opportunistic infections (LOI) in people living with HIV (PWLHA) in the Caribbean, Central, and South America. The study found that LOI occurred in nearly one in 10 patients, with tuberculosis, esophageal candidiasis, and Pneumocystis jirovecii pneumonia being the most common opportunistic infections. The use of protease inhibitor-based regimen, AIDS-defining events during the first 6 months of antiretroviral treatment, starting antiretroviral treatment in earlier years, and treatment switch were associated with a higher risk of LOI.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Review
Veterinary Sciences
Sandra Valeria Inacio, Jancarlo Ferreira Gomes, Alexandre Xavier Falcao, Bianca Martins dos Santos, Felipe Augusto Soares, Saulo Hudson Nery Loiola, Stefani Laryssa Rosa, Celso Tetsuo Nagase Suzuki, Katia Denise Saraiva Bresciani
Summary: The close contact between humans and animals poses a risk for the transmission of infectious diseases, resulting in substantial public health concerns and economic losses worldwide. Current research is focused on developing more sensitive and accurate diagnostic methods for parasitic infections, but there are challenges that need to be overcome in this field.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Review
Cell Biology
Carlos Wilson, Ana Lis Moyano, Alfredo Caceres
Summary: Axon-dendrite formation is a crucial process in neuronal development, involving external and internal signals, gene expression, protein stability, cytoskeleton remodeling, and vesicle trafficking. Various model systems, including hippocampal neuron cultures, C. elegans, D. melanogaster, and in situ imaging in rodents, have been used to study neuronal polarization. The differentiation of neurons from hiPSCs provides a unique opportunity to test hypotheses specific to humans.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Virology
Firas Al-Mubarak, Janet Daly, Denise Christie, Donna Fountain, Stephen P. Dunham
Article
Cell Biology
Suresh V. Kuchipudi, Stephen P. Dunham, Rahul Nelli, Gavin A. White, Vivien J. Coward, Marek J. Slomka, Ian H. Brown, Kin Chow Chang
IMMUNOLOGY AND CELL BIOLOGY
(2012)
Article
Virology
Rahul K. Nelli, Stephen P. Dunham, Suresh V. Kuchipudi, Gavin A. White, Belinda Baquero-Perez, Pengxiang Chang, Amir Ghaemmaghami, Sharon M. Brookes, Ian H. Brown, Kin-Chow Chang
JOURNAL OF VIROLOGY
(2012)
Article
Multidisciplinary Sciences
Eric A. Lefevre, B. Veronica Carr, Charlotte F. Inman, Helen Prentice, Ian H. Brown, Sharon M. Brookes, Fanny Garcon, Michelle L. Hill, Munir Iqbal, Ruth A. Elderfield, Wendy S. Barclay, Simon Gubbins, Mick Bailey, Bryan Charleston
Review
Veterinary Sciences
Rachael Tarlinton, Janet Daly, Stephen Dunham, Julia Kydd
VETERINARY JOURNAL
(2012)
Editorial Material
Veterinary Sciences
R. Tarlinton, J. Daly, J. H. Kydd
VETERINARY JOURNAL
(2013)
Article
Veterinary Sciences
S. M. Williamson, A. W. Tucker, I. S. McCrone, C. A. Bidewell, N. Brons, H. Habernoll, S. C. Essen, I. H. Brown, J. L. N. Wood
Article
Veterinary Sciences
J. H. Kydd, K. Cobb, R. Davis, R. Dean, J. Drinkwater, S. Dunham, R. Flynn, C. Gray, R. Grogono-Thomas, P. Hagan, A. Jefferies, M. Jones, C. Ogden, G. Pearson, N. Robinson, C. Rutland, R. Tarlinton, S. Toetemeyer, J. Wason, R. Whittington, L. Williams, L. Mossop
Article
Genetics & Heredity
Joanna Moreton, Stephen P. Dunham, Richard D. Emes
FRONTIERS IN GENETICS
(2014)
Article
Veterinary Sciences
Scott Jones, Laura Eden, Heather McKay, Nicola Bollard, Stephen Dunham, Peers Davies, Rachael Tarlinton
BMC VETERINARY RESEARCH
(2019)
Article
Microbiology
Scott Jones, Heather McKay, Laura Eden, Nicola Bollard, Stephen Dunham, Peers Davies, Rachael Tarlinton
Summary: Maedi-visna (MV) is a lentiviral disease of sheep that leads to severe production losses. Current diagnostic methods are not entirely accurate due to individual differences and viral variability. However, a specific allele on the TMEM154 E35K SNP has shown evidence of resistance to the virus, suggesting that selective breeding could be a viable strategy for disease control in sheep.
JOURNAL OF MEDICAL MICROBIOLOGY
(2022)
Article
Immunology
Ika Nurzijah, Ola A. Elbohy, Kostya Kanyuka, Janet M. Daly, Stephen Dunham
Summary: Plant-based vaccines provide a new feasibility for preventing avian influenza and Newcastle disease, with the advantages of high efficiency, stability, and safety. Compared to traditional vaccines, plant-derived virus-like particle vaccines have significant benefits, reducing virus shedding and distinguishing between infected and vaccinated birds.
Review
Biochemistry & Molecular Biology
Daria S. Chulpanova, Valeriya V. Solovyeva, Kristina V. Kitaeva, Stephen P. Dunham, Svetlana F. Khaiboullina, Albert A. Rizvanov
Article
Genetics & Heredity
Suresh V. Kuchipudi, Stephen P. Dunham, Kin-Chow Chang
Article
Veterinary Sciences
Suresh V. Kuchipudi, Meenu Tellabati, Sujith Sebastian, Brandon Z. Londt, Christine Jansen, Lonneke Vervelde, Sharon M. Brookes, Ian H. Brown, Stephen P. Dunham, Kin-Chow Chang
VETERINARY RESEARCH
(2014)
Article
Veterinary Sciences
Hagar Hauser
Summary: Separation-related problems (SRPs) are common in companion dogs and clinicians should be able to diagnose and rule out physical diseases that may exhibit similar clinical signs or worsen SRP.
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
(2024)
Article
Veterinary Sciences
Clara Wilson, Dana Ebbecke, Danielle Berger, Cynthia Otto
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
(2024)
Article
Veterinary Sciences
Lisa Radosta
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
(2024)
Article
Veterinary Sciences
Patrizia Piotti, Ludovica Pierantoni, Mariangela Albertini, Federica Pirrone
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
(2024)
Article
Veterinary Sciences
Lena Provoost
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
(2024)
Article
Veterinary Sciences
M. Leanne Lilly, Carlo Siracusa
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
(2024)
Article
Veterinary Sciences
Daniel S. Mills, Fergus M. Coutts, Kevin J. Mcpeake
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
(2024)
Article
Veterinary Sciences
Marta Amat, Susana Le Brech, Xavier Manteca
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
(2024)
Article
Veterinary Sciences
Sagi Denenberg, Karen L. Machin, Gary M. Landsberg
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
(2024)
Article
Veterinary Sciences
Leticia M. S. Dantas, Niwako Ogata
Summary: The stress response has a significant impact on the central nervous system and other systems in the body, contributing to chronic mental and behavioral pathologies as well as increasing the risk for other chronic inflammatory and metabolic diseases. Psychiatric treatments play a role in alleviating fear, stress, and anxiety and improving the quality of life and lifespan for dogs and cats. The availability of safe psychoactive medications allows for effective treatment options in veterinary patients. Clinicians should have a good understanding of the role neurotransmitters and hormones play in emotional processing, cognition, and behavior, as well as the mechanism of action of drugs to ensure appropriate medication selection for each individual patient.
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
(2024)
Editorial Material
Veterinary Sciences
Carlo Siracusa
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
(2024)
Article
Veterinary Sciences
Valarie V. Tynes
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
(2024)
Article
Veterinary Sciences
Amy Learn, Debra Horwitz
Summary: Inappropriate elimination or behavioral periuria/perichezia is a commonly reported feline behavioral problem worldwide. Changes in behavior are often early signs of physical illness and can worsen existing behavioral issues. Determining the cause, whether medical or behavioral, is crucial before implementing appropriate treatments.
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
(2024)
Article
Veterinary Sciences
Jonathan Bowen, Jaume Fatjo
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
(2024)
Article
Veterinary Sciences
Maya Braem
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE
(2024)