Targets and delivery methods for therapeutic angiogenesis in peripheral artery disease

From Bench to Bedside: What Physicians Need to Know About Endothelial Progenitor Cells

(2011) Mayr Matthias et al.   AMERICAN JOURNAL OF MEDICINE

The microRNA-17~92 cluster: Still a miRacle?

(2011) Angelika Bonauer et al.   CELL CYCLE

Effect of Hypoxia-Inducible Factor-1α Gene Therapy on Walking Performance in Patients With Intermittent Claudication

(2011) Mark A. Creager et al.   CIRCULATION

Intraarterial Administration of Bone Marrow Mononuclear Cells in Patients With Critical Limb Ischemia

(2011) Dirk H. Walter et al.   Circulation-Cardiovascular Interventions

Autologous Bone-Marrow Mononuclear Cell Implantation Reduces Long-Term Major Amputation Risk in Patients With Critical Limb Ischemia

(2011) Naomi Idei et al.   Circulation-Cardiovascular Interventions

Interim analysis results from the RESTORE-CLI, a randomized, double-blind multicenter phase II trial comparing expanded autologous bone marrow-derived tissue repair cells and placebo in patients with critical limb ischemia

(2011) Richard J. Powell et al.   JOURNAL OF VASCULAR SURGERY

Effect of fibroblast growth factor NV1FGF on amputation and death: a randomised placebo-controlled trial of gene therapy in critical limb ischaemia

(2011) Jill Belch et al.   LANCET

Transplantation of sendai viral angiopoietin-1-modified mesenchymal stem cells for ischemic limb disease

(2010) Wenhua Piao et al.   ANGIOGENESIS

Combination Stem Cell Therapy for the Treatment of Severe Limb Ischemia: Safety and Efficacy Analysis

(2010) Gabriel P. Lasala et al.   ANGIOLOGY

Embryonic Stem Cell–Derived Endothelial Cells Engraft Into the Ischemic Hindlimb and Restore Perfusion

(2010) Ngan F. Huang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Phase I/IIa Clinical Trial of Therapeutic Angiogenesis Using Hepatocyte Growth Factor Gene Transfer to Treat Critical Limb Ischemia

(2010) Ryuichi Morishita et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Therapeutic angiogenesis by transplantation of induced pluripotent stem cell-derived Flk-1 positive cells

(2010) Hirohiko Suzuki et al.   BMC CELL BIOLOGY

Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling

(2010) S. Rey et al.   CARDIOVASCULAR RESEARCH

Downregulation of microRNA-29 by antisense inhibitors and a PPAR-γ agonist protects against myocardial ischaemia–reperfusion injury

(2010) Yumei Ye et al.   CARDIOVASCULAR RESEARCH

Stem Cell Therapy for Vascular Regeneration

(2010) Nicholas J. Leeper et al.   CIRCULATION

Thioredoxin-1 Gene Therapy Enhances Angiogenic Signaling and Reduces Ventricular Remodeling in Infarcted Myocardium of Diabetic Rats

(2010) Samson Mathews Samuel et al.   CIRCULATION

Genetic Modification of Mesenchymal Stem Cells Overexpressing CCR1 Increases Cell Viability, Migration, Engraftment, and Capillary Density in the Injured Myocardium

(2010) Jing Huang et al.   CIRCULATION RESEARCH

Randomized, double-blind, placebo-controlled clinical trial of hepatocyte growth factor plasmid for critical limb ischemia

(2010) H Shigematsu et al.   GENE THERAPY

Increased perfusion and angiogenesis in a hindlimb ischemia model with plasmid FGF-2 delivered by noninvasive electroporation

(2010) B Ferraro et al.   GENE THERAPY

Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis

(2010) Goutam Ghosh et al.   JOURNAL OF CLINICAL INVESTIGATION

Human Peripheral Blood-Derived CD31+Cells Have Robust Angiogenic and Vasculogenic Properties and Are Effective for Treating Ischemic Vascular Disease

(2010) Sung-Whan Kim et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Targeted Delivery of Nanoparticles to Ischemic Muscle for Imaging and Therapeutic Angiogenesis

(2010) Jaeyun Kim et al.   NANO LETTERS

PGC-1  regulates a HIF2 -dependent switch in skeletal muscle fiber types

(2010) K. A. Rasbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Long-Term Follow-Up Study of Intravenous Autologous Mesenchymal Stem Cell Transplantation in Patients With Ischemic Stroke

(2010) Jin Soo Lee et al.   STEM CELLS

Impact of Nanotechnology on Drug Delivery

(2009) Omid C. Farokhzad et al.   ACS Nano

Endothelial-Specific Expression of Mitochondrial Thioredoxin Promotes Ischemia-Mediated Arteriogenesis and Angiogenesis

(2009) Shengchuan Dai et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Autologous peripheral blood CD133+ cell implantation for limb salvage in patients with critical limb ischemia

(2009) R K Burt et al.   BONE MARROW TRANSPLANTATION

Physical methods of nucleic acid transfer: general concepts and applications

(2009) Julien Villemejane et al.   BRITISH JOURNAL OF PHARMACOLOGY

Regulation of cullin-RING E3 ubiquitin-ligases by neddylation and dimerization

(2009) J. Merlet et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Role of Fibroblast Growth Factors in Tumor Growth

(2009) M. Korc et al.   CURRENT CANCER DRUG TARGETS

Autologous adipose tissue as a new source of progenitor cells for therapeutic angiogenesis

(2009) Toyoaki Murohara   Journal of Cardiology

Comparison of Gene Delivery Techniques for Therapeutic Angiogenesis

(2009) Jeremy Kobulnik et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study of Intravenous Adult Human Mesenchymal Stem Cells (Prochymal) After Acute Myocardial Infarction

(2009) Joshua M. Hare et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Nucleic Acids Electrotransfer-Based Gene Therapy (Electrogenetherapy): Past, Current, and Future

(2009) L. M. Mir   MOLECULAR BIOTECHNOLOGY

Mesenchymal stem cells modified with stromal cell-derived factor 1α improve cardiac remodeling via paracrine activation of hepatocyte growth factor in a rat model of myocardial infarction

(2009) Junming Tang et al.   MOLECULES AND CELLS

Nanoparticulate Systems for Growth Factor Delivery

(2009) Sufeng Zhang et al.   PHARMACEUTICAL RESEARCH

The transcriptional coactivator PGC-1α mediates exercise-induced angiogenesis in skeletal muscle

(2009) Jessica Chinsomboon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice

(2009) A. Bonauer et al.   SCIENCE

Intramuscular Transplantation of G-CSF-Mobilized CD34+Cells in Patients With Critical Limb Ischemia: A Phase I/IIa, Multicenter, Single-Blinded, Dose-Escalation Clinical Trial

(2009) Atsuhiko Kawamoto et al.   STEM CELLS

Induction of HIV-1-specific cellular and humoral immune responses following immunization with HIV-DNA adjuvanted with activated apoptotic lymphocytes

(2009) Andreas Brave et al.   VACCINE

Cell therapies for therapeutic angiogenesis: back to the bench

(2009) Daniel P Sieveking et al.   VASCULAR MEDICINE

Implantation of Adipose-Derived Regenerative Cells Enhances Ischemia-Induced Angiogenesis

(2008) Kazuhisa Kondo et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Disease-Specific Induced Pluripotent Stem Cells

(2008) In-Hyun Park et al.   CELL

Generation of Functional Murine Cardiac Myocytes From Induced Pluripotent Stem Cells

(2008) Christina Mauritz et al.   CIRCULATION

Directed and Systematic Differentiation of Cardiovascular Cells From Mouse Induced Pluripotent Stem Cells

(2008) Genta Narazaki et al.   CIRCULATION

Results of a Double-Blind, Placebo-Controlled Study to Assess the Safety of Intramuscular Injection of Hepatocyte Growth Factor Plasmid to Improve Limb Perfusion in Patients With Critical Limb Ischemia

(2008) Richard J. Powell et al.   CIRCULATION

Paracrine Mechanisms in Adult Stem Cell Signaling and Therapy

(2008) Massimiliano Gnecchi et al.   CIRCULATION RESEARCH

PGC-1 coactivators and skeletal muscle adaptations in health and disease

(2008) Zolt Arany   CURRENT OPINION IN GENETICS & DEVELOPMENT

Using Adult Stem Cells to Treat Heart Failure—Fact or Fiction?

(2008) Hendrik Zimmet et al.   Heart Lung and Circulation

Stemming heart failure with cardiac- or reprogrammed-stem cells

(2008) Kento Tateishi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Phase I Trial of Interleukin-12 Plasmid Electroporation in Patients With Metastatic Melanoma

(2008) Adil I. Daud et al.   JOURNAL OF CLINICAL ONCOLOGY

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL

Therapeutic Angiogenesis With Intramuscular NV1FGF Improves Amputation-free Survival in Patients With Critical Limb Ischemia

(2008) Sigrid Nikol et al.   MOLECULAR THERAPY

Stem-cell-based therapy and lessons from the heart

(2008) Robert Passier et al.   NATURE

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

(2008) Zoltan Arany et al.   NATURE

Targeted Delivery of Nanoparticles Bearing Fibroblast Growth Factor-2 by Ultrasonic Microbubble Destruction for Therapeutic Arteriogenesis

(2008) John C. Chappell et al.   Small

Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques

(2008) Lauren A. Hirao et al.   VACCINE

A Population of Multipotent CD34-Positive Adipose Stromal Cells Share Pericyte and Mesenchymal Surface Markers, Reside in a Periendothelial Location, and Stabilize Endothelial Networks

(2007) Dmitry O. Traktuev et al.   CIRCULATION RESEARCH