Article
Economics
Angela Jornada Ben, Sylvia Pellekooren, Judith E. Bosmans, Raymond W. J. G. Ostelo, Esther T. Maas, Mohamed El Alili, Maurits W. van Tulder, Frank J. P. M. Huygen, Teddy Oosterhuis, Adri T. Apeldoorn, Miranda L. van Hooff, Johanna M. van Dongen
Summary: The study aimed to develop and validate approaches for mapping Oswestry Disability Index responses to 3-level version of EQ-5D utility values and evaluate their impact on cost-utility results compared with published regression models. Three response mapping approaches were developed and their performance was assessed. The results suggest that the developed approaches are not valid for estimating individual patients' utility values and may significantly affect cost-utility results.
Article
Economics
Ben A. van Hout, James W. Shaw
Summary: This research developed algorithms to map EQ-5D-3L responses to EQ-5D-5L value sets and found that including indicants of problems for other dimensions as regressors in the model improved prediction accuracy. Adding age and gender lowered AIC without improving predictions, while including a latent factor slightly improved predictive accuracy. Models conditioning on problems in other dimensions yielded more accurate predictions than an alternative copula-based approach.
Article
Public, Environmental & Occupational Health
Deyu Huang, Jialing Peng, Na Chen, Qing Yang, Longlin Jiang
Summary: This study developed a mapping algorithm to predict EQ-5D-5L health utility scores for Chinese patients with papillary thyroid carcinoma (PTC) and obtained health utility parameters from FACT-H&N. The Beta mixture regression model achieved the best performance in mapping FACT-H&N to EQ-5D-5L. These algorithms can be used for cost-utility analysis in PTC patients.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Allergy
Hiroshi Kumanomidou, Kengo Kanai, Aiko Oka, Takenori Haruna, Yuji Hirata, Sei-ichiro Makihara, Takaya Higaki, Maki Akamatsu, Yoshitaka Okamoto, Shunya Ikeda, Mitsuhiro Okano
Summary: This study developed an algorithm to predict the utility of total naso-ocular symptom score in patients with Japanese cedar pollinosis (JCP) and conducted a cost-utility analysis of sublingual immunotherapy (SLIT) for JCP using this algorithm. The results showed that pre-seasonal SLIT for JCP is cost-effective.
ALLERGOLOGY INTERNATIONAL
(2022)
Article
Health Care Sciences & Services
Epaminondas M. Valsamis, David Beard, Andrew Carr, Gary S. Collins, Stephen Brealey, Amar Rangan, Rita Santos, Belen Corbacho, Jonathan L. Rees, Rafael Pinedo-Villanueva
Summary: In this study, mapping algorithms were developed and evaluated to estimate the EQ-5D health index from the Oxford Shoulder Score (OSS). The multivariable linear and splines models had the lowest mean square error (MSE) in both EQ-5D-3L and EQ-5D-5L analyses, while the SUR models had the lowest mean absolute error (MAE). The models performed the best in the mid-range and best health states.
QUALITY OF LIFE RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Cheng-yao Sun, Yang Liu, Liang-ru Zhou, Ming-si Wang, Xian-ming Zhao, Wei-dong Huang, Guo-xiang Liu, Xin Zhang
Summary: The study compared the utility scores of EQ-5D-3L and SF-6D in family caregivers of colorectal cancer patients. The distribution of scores was not normal, with a ceiling effect observed in EQ-5D-3L but not in SF-6D. There was good association between the two scores and SF-6D showed better discrimination and known-groups validity.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Economics
Svenja Elkenkamp, Kristina Ludwig, Wolfgang Greiner
Summary: This research aimed to determine the robustness of the German EQ-5D-5L valuation data for the general population compared with those with health impairments. The results showed that people with self-reported health impairments do not have different EQ-5D-5L health state preferences compared with the German general population.
Article
Economics
Mihir Gandhi, Ru San Tan, Shir Lynn Lim, Kim Rand, Carolyn S. P. Lam, Nan Luo, Yin Bun Cheung
Summary: This study aimed to investigate the health preferences of patients with heart disease and develop a value set for the 5-level EQ-5D (EQ-5D-5L) based on these patient preferences. The value set could be used for patient-centric economic evaluation and health-related quality of life assessment for patients with heart disease.
Article
Dermatology
Morteza Arab-Zozani, Hossein Safari, Zoha Dori, Somayeh Afshari, Hosein Ameri, Nasim Namiranian, Elham Hoseini, Abdolkhalegh Jafari
Summary: This study estimated utility values of diabetic foot ulcer (DFU) patients using EQ-5D-5L and cTTO, finding anxiety and pain as the most common issues reported by patients. Differences in utility values were significant for age, ulcer grade, number of comorbidities, and complications, with gender, age, ulcer grade, and complications as significant predictors for EQ-5D-5L, and gender, age, ulcer grade, number of comorbidities, and developing complications as significant predictors for cTTO. The study provided estimates for clinical practice and economic modeling, highlighting the importance of addressing anxiety/depression and pain to improve utility values.
INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS
(2022)
Article
Health Care Sciences & Services
Asrul Akmal Shafie, Irwinder Kaur Chhabra, Jacqueline Hui Yi Wong, Noor Syahireen Mohammed
Summary: This study aimed to estimate and derive health state utility values associated with the treatment and complications of transfusion-dependent thalassemia (TDT) patients in Malaysia using the EQ-5D-3L instrument. Findings showed that patients with iron overload complications had lower HRQoL, and patients on oral monotherapy had a higher utility value compared to other regimen combinations.
HEALTH AND QUALITY OF LIFE OUTCOMES
(2021)
Article
Orthopedics
Hadeer Fawaz, Omaima Yassine, Abdullah Hammad, Ramez Bedwani, Ghada Abu-Sheasha
Summary: This study developed and evaluated algorithms to estimate the generic health utility scores (EQ-5D-5L) from the disease-specific OKS, allowing for the computation of QALYs in economic evaluations for knee osteoarthritis patients. Machine learning-based strategies offer a viable alternative for mapping.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Economics
Shitong Xie, Jing Wu, Gang Chen
Summary: This study aimed to compare the performance of EQ-5D-5L and SF-6Dv2 in China and develop mapping algorithms between the two measures. The results showed comparable discriminative validity between the two measures, but EQ-5D-5L generated higher utility values on average. Mapping algorithms were reported to enable transformations between EQ-5D-5L and SF-6Dv2 in China.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2023)
Article
Health Care Sciences & Services
Lee Seng Esmond Seow, Jue Hua Lau, Edimansyah Abdin, Swapna K. Verma, Kelvin Bryan Tan, Mythily Subramaniam
Summary: The current study aimed to map the disease-specific Schizophrenia Quality of Life Scale (SQLS) onto generic preference-based instruments (EQ-5D-3 L, EQ-5D-5 L, HUI3, and SF-6D) to inform cost-utility analyses for schizophrenia treatment.
EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Chuchuan Wan, Qiqi Wang, Zhaoqi Xu, Yuankai Huang, Xiaoyu Xi
Summary: This research aims to develop more accurate mapping algorithms from health assessment questionnaire disability index (HAQ-DI) onto EQ-5D-5L based on Chinese Rheumatoid Arthritis patients. Direct mapping and response mapping were carried out using different regression models. The mapping algorithm based on Beta performed the best according to the evaluation criteria. Researchers can choose the mapping algorithms based on the actual data.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Dermatology
Zhonghua Yang, Shunping Li, Xuewen Wang, Gang Chen
Summary: This study aimed to determine pooled EQ-5D utility scores for psoriasis as a general condition, plaque psoriasis, and psoriatic arthritis. The findings showed that psoriasis has a significant impact on patients' quality of life, especially in the pain/discomfort dimension. However, there is heterogeneity among the EQ-5D utility values found in the literature.
JOURNAL OF DERMATOLOGICAL TREATMENT
(2022)
