Article
Geriatrics & Gerontology
Teck Yong Gabriel Ding, Jacqueline Giovanna De Roza, Cheuk Ying Chan, Poay Sian Sabrina Lee, Sin Kee Ong, Kaiwei Jeremy Lew, Hui Li Koh, Eng Sing Lee
Summary: Singapore is dealing with an ageing population, with a particular need for care among frail older adults with multimorbidity. This study aimed to assess the burden on primary family caregivers of these individuals and identified factors associated with this burden. The findings showed that being a Chinese primary family caregiver and spending more time caregiving per week were positively associated with caregiver burden.
Article
Public, Environmental & Occupational Health
Kun He, Wenli Zhang, Xueqi Hu, Hao Zhao, Bingxin Guo, Zhan Shi, Xiaoyan Zhao, Chunyu Yin, Songhe Shi
Summary: This study aimed to examine the relationship between multimorbidity and all-cause mortality in Chinese older adults. The results showed that there was a positive association between multimorbidity and all-cause mortality risk, with disease clusters having a particularly notable impact.
Article
Medicine, General & Internal
Purva Jain, Alexandra M. Binder, Brian Chen, Humberto Parada, Linda C. Gallo, John Alcaraz, Steve Horvath, Parveen Bhatti, Eric A. Whitsel, Kristina Jordahl, Andrea A. Baccarelli, Lifang Hou, James D. Stewart, Yun Li, Jamie N. Justice, Andrea Z. LaCroix
Summary: This study investigated the association between epigenetic age acceleration (EAA), a biomarker associated with aging, and healthy longevity among older women. The findings suggest that EAA may be a valid biomarker associated with healthy longevity among older women and may be used for risk stratification and risk estimation of future functional and cognitive aging.
Article
Multidisciplinary Sciences
Shahid Shah, Ghulam Abbas, Ayesha Aslam, Fawad Ahmad Randhawa, Faiz Ullah Khan, Haris Khurram, Usman Rashid Chand, Muhammad Hammad Butt, Tauqeer Hussain Mallhi, Yusra Habib Khan
Summary: This study aimed to assess the health-related quality of life (HRQoL) of patients with obesity, hypertension (HTN) and type 2 diabetes (T2D), individually and in combination. A questionnaire-based cross-sectional study was conducted in Punjab, Pakistan. The findings showed that these diseases individually reduced HRQoL, and the presence of multiple diseases had a more detrimental impact on HRQoL.
Article
Geriatrics & Gerontology
Alessandra Marengoni, Roselyne Akugizibwe, Davide L. Vetrano, Albert Roso-Llorach, Graziano Onder, Anna-Karin Welmer, Amaia Calderon-Larranaga
Summary: The study found an association between specific patterns of multimorbidity and risk of disability in older persons. Different multimorbidity patterns were shown to impact the risk of developing basic and instrumental activities of daily living disabilities.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2021)
Article
Geriatrics & Gerontology
Jennifer E. Lutomski, Trynke Hoekstra, Marjan van den Akker, Jeanet Blom, Amaia Calderon-Larranaga, Alessandra Marengoni, Alexandra Prados-Torres, Marcel Olde-Rikkert, Rene Melis, TOPICS-MDS Consortium TOPICS MDS Consortium
Summary: As populations age, multimorbidity becomes increasingly common. This study identified five common patterns of chronic diseases in older persons and examined their effect on quality of life over a one-year period. The results showed that these patterns did not have a significant impact on quality of life.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2023)
Article
Geriatrics & Gerontology
Simon T. de Gans, Gerdinique C. Maessen, Marjolein H. J. van de Pol, Marjan J. van Apeldoorn, Margot A. L. van Ingen-Stokbroekx, Niels van der Sloot, Carolina J. P. W. Keijsers, Babette C. van der Zwaard
Summary: This study evaluated the effects of Intensive Collaboration Ward (ICW) care on older patients with multiple health problems. The findings showed that ICW care reduced in-hospital medical consultations, increased consultations with allied health professionals, and resulted in a change in primary treating specialty for the patients. Overall, ICW care improved the quality and efficiency of care for older patients with multiple health problems.
Article
Geriatrics & Gerontology
David H. Lynch, Curtis L. Petersen, Marco M. Fanous, Hillary B. Spangler, Anna R. Kahkoska, Daniel Jimenez, John A. Batsis
Summary: Obesity is associated with an increased risk of multimorbidity and functional limitations in older adults, according to a study of 7,261 individuals aged 60 and above. Compared to normal weight individuals, older adults with obesity have higher odds of having multimorbidity, and the prevalence of functional limitations also increases with higher body mass index (BMI). Among patients with multimorbidity, 90% of those classified as severely obese (BMI>=40 kg/m²) also had functional limitations.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2022)
Article
Oncology
Winnie K. W. So, Doreen W. H. Au, Dorothy N. S. Chan, Marques S. N. Ng, Kai Chow Choi, Weijie Xing, Mandy Chan, Suzanne S. S. Mak, Pui Shan Ho, Man Tong, Cecilia Au, Wai Man Ling, Maggie Chan, Raymond J. Chan
Summary: This study aimed to investigate whether financial well-being mediates the impact of multimorbidity on the health-related quality of life (HRQoL) of cancer patients. The results showed that multimorbidity had a direct effect on HRQoL, and also had an indirect effect through its impact on financial well-being.
Article
Health Care Sciences & Services
Rachel O'Loughlin, Harriet Hiscock, Tianxin Pan, Nancy Devlin, Kim Dalziel
Summary: This study aimed to investigate the relationships between physical health problems, borderline or clinical levels of mental health symptoms, and children's health-related quality of life (HRQoL). The findings revealed that mental health symptoms were significantly associated with lower HRQoL in children, with a larger impact than physical health problems. Furthermore, the study highlighted the importance of addressing mental health symptoms in children, especially those with physical-mental multimorbidity, who are at higher risk of poorer HRQoL.
QUALITY OF LIFE RESEARCH
(2022)
Article
Clinical Neurology
Zi-Ting Huang, Yan Luo, Ling Han, Kaipeng Wang, Shan-Shan Yao, He-Xuan Su, Sumin Chen, Gui-Ying Cao, Carson M. De Fries, Zi-Shuo Chen, Hui-Wen Xu, Yong-Hua Hu, Beibei Xu
Summary: This study examined the association between cardiometabolic multimorbidity and depressive symptoms among middle-aged and older Chinese. The results showed that stroke, heart disease, and diabetes had individual and additive effects on CMD combinations, while hypertension and dyslipidemia were only associated with depressive symptoms when combined with other CMDs.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Environmental Sciences
Karla Romero Starke, Janice Hegewald, Stefanie Schmauder, Pauline Kaboth, Lena Marie Uhlmann, David Reissig, Kristin Klaudia Kaufmann, Juergen Wegge, Gesine Marquardt, Andreas Seidler
Summary: With the aging population in Europe, it is important to focus on the health of older adults. The LAB60+ study conducted in Dresden, Germany aimed to examine the health and care situation of older adults and assess the impact of age, gender, and socioeconomic status (SES) on health outcomes. The study found a high prevalence of chronic conditions and multimorbidities among the participants, with a significant portion requiring care. Compared to a reference population in Germany, older adults in Dresden had lower health-related quality of life (HRQoL) and well-being, possibly due to the ongoing COVID-19 pandemic. Gender differences were observed in chronic health conditions, with women having a higher risk for lower HRQoL, well-being, and depressivity compared to men. Lower SES was associated with a higher risk of most health outcomes. Socioeconomic factors and gender-related inequalities should be considered for the development of prevention and health-promoting measures in late life.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Multidisciplinary Sciences
Ke Gao, Bo-Lin Li, Lei Yang, Dan Zhou, Kang-Xi Ding, Ju Yan, Ya-Jie Gao, Xiao-Rui Huang, Xiao-Pu Zheng
Summary: This study found significant associations between cardiometabolic diseases and frailty, healthcare utilization, and expenditure among Chinese older adults. As the number of cardiometabolic diseases increased, the prevalence of frailty and healthcare utilization also increased. Individuals with two or more cardiometabolic diseases had a higher likelihood of catastrophic health expenditure, and frail individuals were more likely to report higher healthcare utilization odds.
SCIENTIFIC REPORTS
(2021)
Article
Geriatrics & Gerontology
Yen Ko-Han, Hsu Chia-Chia, Yu Pei-Chin, Liu Hsin-Yu, Chen Zhi-Jun, Chen Yu-Wen, Peng Li-Ning, Lin Ming-Hsien, Chen Liang-Kung
Summary: This study evaluated the determinants of improved quality of life among older adults with multimorbidity who received integrated outpatient services. The results showed that integrated outpatient services improved the overall quality of life in these patients, with poorer nutritional status, depressive symptoms, and frailty identified as independent risk factors for poorer quality of life outcomes.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2021)
Article
Public, Environmental & Occupational Health
Natan Feter, Jayne S. Leite, Daniel Umpierre, Eduardo L. Caputo, Airton J. Rombaldi
Summary: The study found that leisure-time physical activity during adolescence and mid-adult life had a stronger impact on the risk of multimorbidity at age 55. Physical activity during adolescence was found to have a critical independent effect on the risk of multimorbidity.
