Journal
VACCINE
Volume 29, Issue 16, Pages 2836-2839Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.vaccine.2011.02.020
Keywords
HIV; Influenza A (H1N1); Swine flu; Vaccination; Immunogenicity
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Immunogenicity of influenza A (H1N1)v MF59-adjuvanted vaccine was studied in HIV-infected patients. The vaccine was effective in inducing a protective immune response in patients with a CD4 > 200 cells/mu L while individuals with CD4 < 200 cells/mu L showed lower rates of seroconversion and seroprotection. These results underscore the usefulness of immunization against influenza in HIV-infected patients, though a boosting dose of vaccine may be required in seriously immunocompromised patients. (C) 2011 Elsevier Ltd. All rights reserved.
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