Article
Immunology
Xiaoping Shao, Xinyue Lu, Weiyu Zhou, Weifeng Huang, Yihan Lu
Summary: This study aimed to determine the HPV vaccination behavior and preference in Chinese female health care workers. The survey results showed that 30.0% of the respondents have been vaccinated or have made an appointment for HPV vaccination. The 9-valent HPV vaccine was the most preferred vaccine among the respondents.
Article
Biotechnology & Applied Microbiology
Tsegaw Biyazin, Ashenafi Yilma, Aynalem Yetwale, Belete Fenta, Yalemtsehay Dagnaw
Summary: The study aimed to investigate knowledge and attitudes towards HPV vaccination among female high-school students. The results showed that overall knowledge and attitude towards HPV vaccination were low, and factors such as parents' educational status, participation in school media activities, and smartphone ownership were significantly associated with knowledge. The study suggests a collaborative effort to enhance knowledge and attitudes towards HPV vaccination among female students.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2022)
Article
Immunology
Lauri E. Markowitz, John T. Schiller
Summary: HPV vaccines are highly effective in preventing HPV-attributable cancers and have been introduced into national immunization programs in over 100 countries. The success of these vaccines has sparked interest in ambitious disease reduction goals.
JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Public, Environmental & Occupational Health
Doreen Ramogola-Masire, Nancy McClung, Anikie Mathoma, Julia W. Gargano, Naledi Gape Nyepetsi, Troy D. Querec, Juanita Onyekwuluje, Madisa Mine, Chelsea Morroni, Rebecca Luckett, Lauri E. Markowitz
Summary: In this study, we aimed to establish the baseline HPV prevalence in unvaccinated young adults in Botswana. The results showed that women had significantly higher prevalence of any HPV type, vaccine-type HPV, and non-vaccine-type HPV compared to men. Having two or more sex partners in the past 12 months was associated with higher prevalence of any HPV type in both men and women, while always using condoms in the past 3 months was associated with lower HPV prevalence.
EPIDEMIOLOGY AND INFECTION
(2022)
Article
Mathematical & Computational Biology
Mo'tassem Al-Arydah
Summary: A two-gender model was formulated to find optimal childhood and catch-up vaccines for minimizing Human Papillomavirus (HPV) disease costs over a 20-year period. The optimal vaccines should keep R0 <= 1 and gradually decrease over time to achieve minimal cost and control HPV effectively.
INTERNATIONAL JOURNAL OF BIOMATHEMATICS
(2021)
Article
Public, Environmental & Occupational Health
Catharine Chambers, Shelley L. Deeks, Rinku Sutradhar, Joseph Cox, Alexandra de Pokomandy, Troy Grennan, Trevor A. Hart, Gilles Lambert, David M. Moore, Daniel Grace, Ramandip Grewal, Jody Jollimore, Nathan J. Lachowsky, Ashley Mah, Rosane Nisenbaum, Gina Ogilvie, Chantal Sauvageau, Darrell H. S. Tan, Anna Yeung, Ann N. Burchell
Summary: Self-reported human papillomavirus (HPV) vaccination has limitations in terms of accuracy. This study investigated the impact of misclassification associated with self-reported vaccination on the estimates of vaccine effectiveness (VE). The results showed that bias-corrected VE estimates were relatively stable across different sensitivity values, but differed from the uncorrected estimate at lower specificity values. The study concluded that a large proportion of participants would need to erroneously report HPV vaccination in order to significantly change VE estimates.
Article
Immunology
Sahil Khan Warsi, Siff Malue Nielsen, Barbara A. K. Franklin, Shukhrat Abdullaev, Dilfuza Ruzmetova, Ravshan Raimjanov, Khalida Nagiyeva, Kamola Safaeva
Summary: This study investigated the knowledge and decision-making factors of Uzbekistan people towards the Human Papillomavirus (HPV) vaccine. The results showed that participants had awareness of cervical cancer as a national health issue but had limited knowledge about HPV and the vaccine. They desired credible information on the vaccine's safety and efficacy and expressed concerns about its potential impact on young girls' future fertility. Trust in healthcare workers and the government as information sources, as well as collaborations among schools, municipalities, and polyclinics, could facilitate vaccine acceptance and uptake.
Article
Public, Environmental & Occupational Health
Jie Wu, Cheng Ding, Xiaoxiao Liu, Yuqing Zhou, Guo Tian, Lei Lan, Can Chen, Danying Yan, Chenyang Huang, Xiaofang Fu, Lanjuan Li, Shigui Yang
Summary: The study found that the global prevalence of HPV among female sex workers is 39.5%, with significant variations across WHO regions and countries. The five most common HPV types among female sex workers globally are HPV16, HPV52, HPV89, HPV58, and HPV53. The findings suggest that female sex workers are disproportionately affected by HPV, particularly in the Western Pacific and African regions, and require prevention, treatment, and care services.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Multidisciplinary Sciences
Imran O. Morhason-Bello, Kathy Baisley, Miquel A. Pavon, Isaac F. Adewole, Rasheed A. Bakare, Silvia de Sanjose, Suzanna C. Francis, Deborah Watson-Jones
Summary: This study investigated the prevalence and concordance of HPV infections in different anatomical sites among female sex workers in Ibadan, Nigeria. The results showed a high prevalence of HPV infections in cervical, vulval, oral, and anal sites, with HPV 35 being the most prevalent high-risk type. The risk factors for HPV infection varied across different anatomical sites.
Article
Public, Environmental & Occupational Health
Po-Yi Yao, Chung-Ying Lin, Nai-Ying Ko, Huachun Zou, Chia-Wen Lee, Carol Strong
Summary: This study examines the relationship between HPV screening results, HPV-related knowledge and attitudes, and vaccination intention and behavior among MSM. The findings suggest that HPV knowledge and a positive screening result can predict vaccination intention and uptake, regardless of vaccine price.
Article
Immunology
Nchang'wa Nhumba, Bruno Sunguya
Summary: Cervical cancer is a major health issue in Tanzania, and the HPV vaccine is an effective intervention. However, the uptake of the second dose of the vaccine is low, with factors such as age, attitude, and awareness influencing the uptake.
Article
Immunology
John D. Seeger, Kandace L. Amend, Bruce R. Turnbull, Li Zhou, Morgan A. Marks, Christine Velicer, Patricia Saddier
Summary: This study assessed the risk of new onset autoimmune conditions among males receiving the 4-valent human papillomavirus (HPV) vaccine (4vHPV), and the results showed that the incidence of autoimmune conditions among vaccinated males was similar to that among unvaccinated males.
Article
Medicine, General & Internal
Giulia Ciccarese, Astrid Herzum, Gaetano Serviddio, Corrado Occella, Aurora Parodi, Francesco Drago
Summary: HPV vaccines may have a therapeutic role in addition to standard treatments for anogenital warts and oral warts, especially for persistent lesions.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Immunology
Alex Mphuru, Anyie J. Li, Furaha Kyesi, William Mwengee, Fikiri Mazige, Raphael Nshunju, Berrington Shayo, Mary Rose Giattas, Anagha Loharikar, Dafrossa Lyimo
Summary: This study highlights Tanzania's efforts in preventing cervical cancer, including the introduction of HPV vaccines and the accomplishment of most of the planned vaccination. The work involved collaboration between government departments, the World Health Organization, and other partners, with training and meetings conducted at various levels for advocacy and promotion. While the coverage for the first dose of the vaccine is relatively high, efforts are still needed to improve the uptake of the second dose.
Article
Biotechnology & Applied Microbiology
Kandace L. Amend, Bruce Turnbull, Li Zhou, Morgan A. Marks, Christine Velicer, Patricia Saddier, John D. Seeger
Summary: This study assesses the safety of the 4-valent HPV vaccine in males and finds associations with same-day allergic reactions, ear infections, intracranial injury, cellulitis, and concussion. However, other adverse outcomes are determined to be more likely related to activities common in adolescent males rather than the vaccination itself.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2022)
Letter
Biotechnology & Applied Microbiology
Brandon Brown, Alejandra Cabral
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2020)
Article
Biotechnology & Applied Microbiology
Betania Allen-Leigh, Leonor Rivera-Rivera, Elsa Yunes-Diaz, Alejandra Jalil Portillo-Romero, Brandon Brown, Leith Leon-Maldonado, Galileo Vargas-Guadarrama, Jorge Salmeron, Eduardo Cesar Lazcano-Ponce
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2020)
Editorial Material
Ethics
Emily E. Anderson, Brandon Brown
AMERICAN JOURNAL OF BIOETHICS
(2021)
Editorial Material
Public, Environmental & Occupational Health
Brandon Brown, Jeff Taylor, Celia B. Fisher
PUBLIC HEALTH REPORTS
(2021)
Article
Health Care Sciences & Services
Jerome T. Galea, Karah Y. Greene, Brandon Nguyen, Andrea N. Polonijo, Karine Dube, Jeff Taylor, Christopher Christensen, Zhiwei Zhang, Brandon Brown
Summary: Research aims to characterize stakeholders' views on incentives in biomedical HIV research, reach consensus on factors affecting incentive choices, and pilot-test guidance for choosing incentives. The methods include engaging with a stakeholder advisory board, conducting a nationwide survey, and collecting qualitative data through focus groups and interviews. The ultimate goal is to establish a decision-making paradigm for ethical recruitment of clinical research participants.
JMIR RESEARCH PROTOCOLS
(2021)
Article
Nursing
Michelle Didero, Alejandra Cabral, Andrea N. Polonijo, Poorna Kushalnagar, Brandon Brown
JANAC-JOURNAL OF THE ASSOCIATION OF NURSES IN AIDS CARE
(2022)
Article
Biotechnology & Applied Microbiology
Andrea N. Polonijo, Stephanie S. Lee, Nikita Nagpal, Rebecca Barros, Suellen Hopfer, Brandon Brown, Harry Pellman, Jasjit Singh
Summary: Strong doctor recommendation and information dissemination about the importance of HPV vaccination are the most important drivers of vaccine acceptance. Reasons for vaccine acceptance vary by gender, language, and clinic type.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2021)
Article
Health Policy & Services
Jerome T. Galea, Stephanie Marhefka, Segundo R. Leon, Guitele Rahill, Elena Cyrus, Hugo Sanchez, Zhiwei Zhang, Brandon Brown
Summary: Depression disproportionately affects those at risk of HIV and is associated with worse health outcomes, yet integration of depression care with HIV services in Peru should target mild to moderate depression for intervention.
AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV
(2022)
Article
Public, Environmental & Occupational Health
Andrea N. Polonijo, Shawna Sein, Raul Maldonado, Jorge Delos Santos, Brandon Brown
Summary: Community-based rapid HIV testing is effective for reaching racially and ethnically diverse men who have sex with men. However, bundling health promotion messages with rapid HIV testing may be ineffective as the anxiety associated with the test may interfere with the impact of the health promotion messages.
HEALTH & SOCIAL CARE IN THE COMMUNITY
(2022)
Article
Public, Environmental & Occupational Health
Andrea N. Polonijo, Karine Dube, Jerome T. Galea, Karah Yeona Greene, Jeff Taylor, Christopher Christensen, Brandon Brown
Summary: This study examined the attitudes and preferences of people living with HIV towards payment in research participation. The findings suggest that payment can influence individuals' decisions to participate and their perception of study risks, and that different sociodemographic groups may have different preferences and reactions to payment.
Article
Public, Environmental & Occupational Health
Andrea N. Polonijo, Durga Mahapatra, Brandon Brown
Summary: The study aimed to identify knowledge, attitudes, and beliefs related to HPV and HPV vaccination among women aged 27-45 years. The findings highlighted diverse perspectives, including concerns about vaccine safety, low perceived benefits of vaccination, and social factors influencing acceptance. While some participants saw vaccination as a way to exercise control over their health, others associated it with social stigma.
WOMENS HEALTH ISSUES
(2022)
Editorial Material
Immunology
Jasmine L. L. Lopez, Andrea N. N. Polonijo, Annie L. L. Nguyen, Karah Y. Y. Greene, Jerome T. T. Galea, Moka Yoo-Jeong, Jeff Taylor, Brandon J. J. Brown
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY
(2023)
Article
Infectious Diseases
Karine Dube, John Kanazawa, Lynda Dee, Jeff Taylor, Danielle M. Campbell, Brandon Brown, Mallory O. Johnson, Parya Saberi, John A. Sauceda, Jeremy Sugarman, Michael J. Peluso
Summary: The study highlights the importance of ethical considerations and risk mitigation strategies to reduce unintended HIV transmission events during Analytical Treatment Interruptions (ATIs) in HIV cure-related research. Despite uncertainties in managing sexually transmitted infections and protecting multiple or anonymous partners of ATI trial participants, providing adequate support, counseling, and referral to pre-exposure prophylaxis are crucial in protecting the welfare of individuals involved in such trials. Ethical permissibility of ATI trials relies on due diligence and informed consent to mitigate risks to participants and their sexual partners.
HIV RESEARCH & CLINICAL PRACTICE
(2021)
Article
Gerontology
Logan Z. Marg, Griselda Ruiz, Fidel Chagolla, Alejandra Cabral, Jeff Taylor, Chris Christensen, Marjorie Martin, Bridgette Picou, Brandon Brown
JOURNAL OF WOMEN & AGING
(2020)
Article
Ethics
Roberto Abadie, Brandon Brown, Celia B. Fisher