Re: Global serotype distribution among Streptococcus pneumoniae isolates causing otitis media in children: Potential implications for pneumococcal conjugate vaccines

Acute otitis media (AOM) is one of the most commonly diagnosed childhood infections. Analysis of global serotype distribution among Streptococcus pneumonia isolates causing otitis media in children may improve coverage of future pneumococcal conjugate vaccines. Serotypes like 3 or 19A should not only be included in future vaccine formulations but they should preferably protect against these serotypes. To construct future AOM vaccine with higher vaccine efficacy also other pathogens causing AOM need to be taken into consideration. (C) 2009 Elsevier Ltd. All rights reserved.