Journal
VACCINE
Volume 27, Issue 18, Pages 2408-2409Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.vaccine.2009.02.049
Keywords
Yellow fever vaccine; Egg allergy; Intradermal test dose
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The neutralising antibody response after the yellow fever vaccine (YF-17D) skin test was measured in 7 egg allergic persons in whom further vaccination was abandoned because of a strong local urticarial reaction to the YF-17D vaccine test dose. We found that this test dose of 0.1 mL of YF-17D vaccine was sufficient to induce a protective antibody response in all 7 subjects. Intradermal injection of 1/5th dose of the yellow fever vaccine appears to be sufficient, in non-allergic as well as allergic persons, and non-inferior to the subcutaneous full dose. (C) 2009 Elsevier Ltd. All rights reserved.
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