Article
Medicine, General & Internal
Yao-Lin Kao, Chien-Hui Ou, Sheng-Hsiang Lin, Sheng-Mao Chang, Jung-Der Wang, Yuh-Shyan Tsai
Summary: This study assessed the dynamic changes of quality of life in patients with localized prostate cancer under different treatment modalities. Factors such as lower household incomes and comorbidities of anxiety or diabetes were found to negatively impact patients' quality of life. Patients under active surveillance or observation demonstrated higher quality of life scores in the physical and social domains compared to those undergoing radical prostatectomy or radiotherapy within the first year.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Szu-Yuan Wu, Fransisca Fortunata Effendi, Ricardo E. Canales, Chung-Chien Huang
Summary: This study compared the oncological prognosis of very old patients with acute vulnerable localized prostate cancer (AV-LPC) after they underwent either radical prostatectomy (RP) or massive-dose intensity-modulated radiotherapy (IMRT) coupled with long-term androgen deprivation therapy (ADT). The results showed that RP provides a more favorable oncological prognosis in very old adults with AV-LPC.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Jialin Liu, Huimin Xie, Ting Lin, Congxiao Tie, Huolin Luo, Boyun Yang, Dongjin Xiong
Summary: This study analyzed the genetic variation, population structure, and genetic diversity of soybean cultivars bred in the Huang-Huai-Hai region using genome-wide resequencing data. The results revealed a considerable number of genetic variants in important genomic regions. The cultivars were divided into five subpopulations based on their breeding years, and significant differences in genetic diversity were observed among different breeding periods.
SCIENTIFIC REPORTS
(2022)
Review
Oncology
David Cantarero-Prieto, Javier Lera, Paloma Lanza-Leon, Marina Barreda-Gutierrez, Vicente Guillem-Porta, Luis Castelo-Branco, Jose M. Martin-Moreno
Summary: Prostate cancer is a common and impactful disease for men, with no clear consensus on the most effective treatment strategy. This article analyzes data from OECD countries to characterize the economic burden and cost-effectiveness of different treatment strategies for localized prostate cancer.
Article
Multidisciplinary Sciences
Hong Bae Kim, Chu Hui Zeng, Yunlim Kim, Seung Jeong, Song Hee Kim, Jeon Min Kang, Yubeen Park, Dong-Sung Won, Ji Won Kim, Dae Sung Ryu, Bumjin Lim, Jung-Hoon Park
Summary: The effects of different applied voltages of irreversible electroporation (IRE) on prostate cancer were evaluated. A lasting effect of tumor growth inhibition was observed in the 900 V (1800 V/cm) group. The experiment also confirmed IRE-induced apoptosis in the treatment groups.
SCIENTIFIC REPORTS
(2022)
Article
Neurosciences
Rasha H. Mehder, Brian M. Bennett, R. David Andrew
Summary: This study investigated the relationship between oxidative damage in the dorsal hippocampal CA1 region and progressive cognitive impairment in a mouse model of Alzheimer's disease. Results showed that increased oxidative damage preceded synaptic trimming and may be associated with alterations in neuronal structure leading to cognitive decline.
JOURNAL OF ALZHEIMERS DISEASE
(2021)
Article
Oncology
Gencay Hatiboglu, Valentin Popeneciu, David Bonekamp, Mathieu Burtnyk, Robert Staruch, Florian Distler, Jan Philipp Radtke, Johann Motsch, Heinz Peter Schlemmer, Sascha Pahernik, Joanne Nyarangi-Dix
Summary: This study investigated the 24-month outcomes of men with low to intermediate-risk prostate cancer treated with MRI-guided transurethral ultrasound ablation. The study found that conservative versus intensified treatment parameters did not significantly impact safety or functional outcomes, but could reduce the recurrence rate of clinically significant disease. Careful patient selection and routine follow-up are recommended for treatment success.
FRONTIERS IN ONCOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Ruimin Hu, Yang Yang, Guojing Song, Fuhan Zhao, Saipeng Chen, Zhansong Zhou, Jun Zheng, Wenhao Shen
Summary: This study explored the targeting abilities of nanoparticles with different physicochemical properties towards inflammatory prostate tissues of chronic bacterial prostatitis, with a focus on the effects of size and different modification ligands. The results showed that folic acid-modified nanoparticles with a particle size of 180-190 nm had the optimal targeting efficiency when administered via tail intravenous injection.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Oncology
Zhen Zhou, Feng Yue, Liang Jin, Xiang Liu, Ting-Shuai Zhai, Jia-Xin Zhang, Wen-Yu Gu, Sheng-Hua Liu, Ming Luo, Bo Peng, Xu-Dong Yao, Lin Ye
Summary: This study aimed to evaluate the role of tumor size in predicting tumor risk for localized prostate cancer patients undergoing radical prostatectomy. The results showed a close relationship between tumor size and PCa risk.
Article
Oncology
Bianca Nowlan, Elizabeth D. Williams, Michael Robert Doran
Summary: The study evaluated the impact of partially humanizing mouse bone marrow with human bone marrow-derived stromal cells on human prostate cancer cell behavior. Results showed that PC-3-DsRed cells preferentially populated bones in mice that had received human BMSC, and there were more bone lesions in these mice.
Article
Oncology
M. Shamin, P. S. Kyzlasov, E. Pomeshkin, E. A. Bezrukov
Summary: This study assessed the impact of different types of radical prostatectomy on the erectile function and quality of life of localized prostate cancer patients, as well as the safety of cancer progression. The results showed that bilateral nerve-sparing prostatectomy had the best outcomes in terms of preserving erectile function, while the group without nerve-sparing had the most significant decrease in erection level. The nerve-sparing group also had higher overall satisfaction and quality of life compared to the non-nerve-sparing group.
Article
Developmental Biology
Junchao Shi, Qi Chen, Xin Li, Xiudeng Zheng, Ying Zhang, Jie Qiao, Fuchou Tang, Yi Tao, Qi Zhou, Enkui Duan
Article
Multidisciplinary Sciences
Qi Chen, Menghong Yan, Zhonghong Cao, Xin Li, Yunfang Zhang, Junchao Shi, Gui-hai Feng, Hongying Peng, Xudong Zhang, Ying Zhang, Jingjing Qian, Enkui Duan, Qiwei Zhai, Qi Zhou
Review
Biochemistry & Molecular Biology
Ying Zhang, Qiang Wang, Hongmei Wang, Enkui Duan
TRENDS IN MOLECULAR MEDICINE
(2017)
Article
Cell Biology
Yunfang Zhang, Xudong Zhang, Junchao Shi, Francesca Tuorto, Xin Li, Yusheng Liu, Reinhard Liebers, Liwen Zhang, Yongcun Qu, Jingjing Qian, Maya Pahima, Ying Liu, Menghong Yan, Zhonghong Cao, Xiaohua Lei, Yujing Cao, Hongying Peng, Shichao Liu, Yue Wang, Huili Zheng, Rebekah Woolsey, David Quilici, Qiwei Zhai, Lei Li, Tong Zhou, Wei Yan, Frank Lyko, Ying Zhang, Qi Zhou, Enkui Duan, Qi Chen
NATURE CELL BIOLOGY
(2018)
Article
Reproductive Biology
Jingjing Qian, Yunfang Zhang, Yongcun Qu, Liwen Zhang, Junchao Shi, Xudong Zhang, Shichao Liu, Bo Hyun Kim, Sung Jin Hwang, Tong Zhou, Qi Chen, Sean M. Ward, Enkui Duan, Ying Zhang
BIOLOGY OF REPRODUCTION
(2018)
Article
Cell Biology
Shuang Zhang, Shuangbo Kong, Bingyan Wang, Xiaohong Cheng, Yongjie Chen, Weiwei Wu, Qiang Wang, Junchao Shi, Ying Zhang, Shumin Wang, Jinhua Lu, John P. Lydon, Francesco DeMayo, Warren S. Pear, Hua Han, Haiyan Lin, Lei Li, Hongmei Wang, Yan-Ling Wang, Bing Li, Qi Chen, Enkui Duan, Haibin Wang
Letter
Cell Biology
Ying Zhang, Qi Chen, He Zhang, Qiang Wang, Rong Li, Yaping Jin, Haibin Wang, Tonghui Ma, Jie Qiao, Enkui Duan
Article
Multidisciplinary Sciences
He Zhang, Ying Zhang, Huashan Zhao, Yunfang Zhang, Qi Chen, Hongying Peng, Li Lei, Jingqiao Qiao, Junchao Shi, Zhonghong Cao, Enkui Duan, Yaping Jin
Article
Multidisciplinary Sciences
Shan Lu, Hongying Peng, He Zhang, Li Zhang, Qichen Cao, Rong Li, Ying Zhang, Liying Yan, Enkui Duan, Jie Qiao
Letter
Cell Biology
Yunfang Zhang, Ying Zhang, Junchao Shi, He Zhang, Zhonghong Cao, Xuan Gao, Wanhua Ren, Yunna Ning, Lina Ning, Yujing Cao, Yongchang Chen, Weizhi Ji, Zi-jiang Chen, Qi Chen, Enkui Duan
JOURNAL OF MOLECULAR CELL BIOLOGY
(2014)
Editorial Material
Reproductive Biology
Ying Zhang, Enkui Duan
BIOLOGY OF REPRODUCTION
(2019)
Review
Developmental Biology
Ying Zhang, Qi Chen
Article
Biology
Ying Zhang, Jingjing Qian, Oren Zaltzhendler, Mustafa Bshara, Ariel J. Jaffa, Dan Grisaru, Enkui Duan, David Elad
Editorial Material
Endocrinology & Metabolism
Ying Zhang, Qi Chen
NATURE REVIEWS ENDOCRINOLOGY
(2020)
Review
Endocrinology & Metabolism
Jingjing Qian, Qi Chen, Sean M. Ward, Enkui Duan, Ying Zhang
TRENDS IN ENDOCRINOLOGY AND METABOLISM
(2020)