Phosphatidylinositol 3-Kinase Inhibitor LY294002 Suppresses Proliferation and Sensitizes Doxorubicin Chemotherapy in Bladder Cancer Cells

Cancer Statistics, 2009

(2009) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Emerging targeted therapies for bladder cancer: a disease waiting for a drug

(2009) Simon J. Dovedi et al.   CANCER AND METASTASIS REVIEWS

PI3K Regulatory Subunits Lose Control in Cancer

(2009) Inma Martin-Berenjeno et al.   CANCER CELL

Naphtho[1,2-b]furan-4,5-dione inactivates EGFR and PI3K/Akt signaling pathways in human lung adenocarcinoma A549 cells

(2009) Jung-Chen Su et al.   LIFE SCIENCES

Targeting the phosphoinositide 3-kinase pathway in cancer

(2009) Pixu Liu et al.   NATURE REVIEWS DRUG DISCOVERY

Effects of LY294002 on the invasiveness of human gastric cancer in vivo in nude mice

(2009) Chun-Gen Xing et al.   WORLD JOURNAL OF GASTROENTEROLOGY

LY294002 inhibits leukemia cell invasion and migration through early growth response gene 1 induction independent of phosphatidylinositol 3-kinase-Akt pathway

(2008) Peng Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A chemical screen in diverse breast cancer cell lines reveals genetic enhancers and suppressors of sensitivity to PI3K isoform-selective inhibition

(2008) Neil E. Torbett et al.   BIOCHEMICAL JOURNAL

NVP-BEZ235, a Dual PI3K/mTOR Inhibitor, Prevents PI3K Signaling and Inhibits the Growth of Cancer Cells with Activating PI3K Mutations

(2008) V. Serra et al.   CANCER RESEARCH

Phosphatidylinositol 3-Kinase Inhibition Broadly Sensitizes Glioblastoma Cells to Death Receptor- and Drug-Induced Apoptosis

(2008) D. Opel et al.   CANCER RESEARCH

UGT1A7 haplotype is associated with an increased risk of hepatocellular carcinoma in hepatitis B carriers

(2008) Sun-Young Kong et al.   CANCER SCIENCE

Targeting the PI3K/Akt/mTOR pathway: Effective combinations and clinical considerations

(2008) J LOPICCOLO et al.   DRUG RESISTANCE UPDATES

Overexpression of cFLIPs inhibits oxaliplatin-mediated apoptosis through enhanced XIAP stability and Akt activation in human renal cancer cells

(2008) Shin Kim et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Modulating effect of the PI3-kinase inhibitor LY294002 on cisplatin in human pancreatic cancer cells

(2008) Masao Fujiwara et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Discovery of a novel class of AKT pleckstrin homology domain inhibitors

(2008) D. Mahadevan et al.   MOLECULAR CANCER THERAPEUTICS

OSU-03012 Stimulates PKR-Like Endoplasmic Reticulum-Dependent Increases in 70-kDa Heat Shock Protein Expression, Attenuating Its Lethal Actions in Transformed Cells

(2008) M. A. Park et al.   MOLECULAR PHARMACOLOGY

Intravesical Treatments of Bladder Cancer: Review

(2008) Zancong Shen et al.   PHARMACEUTICAL RESEARCH