Article
Food Science & Technology
Neetu Singh, Surender Singh Yadav, Sanjiv Kumar, Balasubramaniam Narashiman
Summary: Trigonella foenum-graecum is widely used for culinary and clinical purposes. It has pharmacological effects attributed to its diverse phytoconstituents. Nanoparticle synthesis can enhance its pharmacological efficacy. Clinical studies have validated its therapeutic potential in diabetes and reproductive health.
Article
Biochemistry & Molecular Biology
Avinash Kumar, Vinay Kumar Singh, Arvind M. Kayastha
Summary: This study determined the three-dimensional structure of fenugreek α-amylase using homology modeling and analyzed its molecular basis and mode of action through molecular dynamics simulations and molecular docking. The study identified functional groupings and binding interactions between the enzyme and its substrate maltose. The research provides valuable insights into the atomic-level molecular underpinnings of α-amylase interaction with maltose.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Environmental Sciences
Javed Ahmad, Md Amjad Beg, Arlene A. Ali, Asma A. Al-Huqail, M. Irfan Qureshi
Summary: Arsenic contamination has detrimental effects on the physiology, growth, and yield of Trigonella foenum-graecum by increasing oxidative stress and decreasing photosynthetic parameters. The plant responds to arsenic toxicity by enhancing antioxidant potential and accumulating specific metabolites.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Biotechnology & Applied Microbiology
Bekir Ahmet Ilgar, Sibel Ozden, Fatma Elif Cepni Yuzbasioglu, Neslihan Turgut Kara
Summary: Yeast extract was found to increase diosgenin levels in fenugreek cell suspension cultures. Additionally, it led to increased expression of the CYP86A2 gene and diosgenin content. The study also explored changes in the expression of key enzyme genes involved in diosgenin formation.
PLANT CELL TISSUE AND ORGAN CULTURE
(2021)
Review
Plant Sciences
Pushpa Ruwali, Niharika Pandey, Khusboo Jindal, Rahul Vikram Singh
Summary: Fenugreek, a herb with medicinal and nutraceutical values, contains various bioactive compounds and possesses antibiotic, antioxidant, anti-carcinogenic properties, as well as the ability to control hyperglycemia in diabetic patients.
SOUTH AFRICAN JOURNAL OF BOTANY
(2022)
Article
Chemistry, Applied
Thierry Hellebois, Claire Gaiani, Jennyfer Fortuin, Alexander Shaplov, Christos Soukoulis
Summary: Cryotropic gelation is a common method to design novel hydrogels with multifaceted functionalities. This study focused on the formation of physically crosslinked hydrogels using highly galactosyl-substituted galactomannans like fenugreek and alfalfa gum via cryogenic processing. Results showed that alfalfa gum-based cryogels had higher elasticity and stiffness compared to fenugreek counterparts, and blending with locust bean gum enhanced the mechanical properties without altering microstructural aspects significantly.
CARBOHYDRATE POLYMERS
(2021)
Article
Environmental Sciences
Javed Ahmad, Rubina Yasmeen, Mohammad Irfan, Asma A. Al-Huqail, Mohammad Irfan Qureshi
Summary: Traces of arsenic in vegetables and crops cultivated in arsenic-polluted soils are a global concern due to its carcinogenic properties and harmful effects on the food chain. This study focused on the accumulation and defense mechanisms of fenugreek plants exposed to arsenic stress. The findings showed increased oxidative stress and DNA damage at higher arsenic concentrations.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Plant Sciences
Mohammad Hossein Banakar, Hamzeh Amiri, Mohammad Reza Sarafraz Ardakani, Gholam Hassan Ranjbar
Summary: The greenhouse experiments investigated the effects of soil salinity on physiological and biochemical attributes of fenugreek, revealing significant impacts on leaf area, relative water content, water use efficiency, leaf thickness, greenness index, and leaf soluble protein. Salinity also influenced sodium content, electrolyte leakage, malondialdehyde (MDA), and other aldehydes in the plant.
ENVIRONMENTAL AND EXPERIMENTAL BOTANY
(2022)
Article
Plant Sciences
Reda E. Abdelhameed, Arafat Abdel Hamed Abdel Latef, Rania S. Shehata
Summary: Foliar application of salicylic acid improves salt tolerance of fenugreek plants by increasing chlorophyll content index and reducing malondialdehyde content, while promoting accumulation of proline, total phenolics, and flavonoids. Additionally, it enhances total free amino acids and shikimic acid, and activates antioxidant enzymes such as ascorbate peroxidase, peroxidase, polyphenol oxidase, and catalase.
Article
Agricultural Engineering
Hamzeh Amiri, Mohammad Hossein Banakar, Gholam Hassan Ranjbar, Mohammad Reza Sarafraz Ardakani, Mahtab Omidvari
Summary: The objective of this study was to investigate the effect of plant growth regulators on fenugreek under saline conditions. The results showed that appropriate concentrations of spermidine and methyl jasmonate could significantly mitigate the adverse effects of salinity stress and improve the growth of fenugreek.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Food Science & Technology
Neeraj Ghanghas, Pramod K. Prabhakar, Shikha Sharma, M. T. Mukilan
Summary: Microfluidization treatment improved the properties of fenugreek seed proteins significantly, including color, oil binding capacity, emulsion stability, and viscoelasticity. Additionally, it also affected the denaturation temperature and linear viscoelastic range of the proteins.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Plant Sciences
Fariba Mohammadifard, Ameneh Tarakemeh, Mohammad Moghaddam, Maryam Zim
Summary: Water scarcity poses a serious threat to agricultural cropping systems of arid and semi-arid regions. Bentonite can effectively improve water utilization in crop production and increase drought tolerance.
JOURNAL OF SOIL SCIENCE AND PLANT NUTRITION
(2022)
Review
Immunology
Zeinab Faghfoori, Zeinab Javadivala, Yeganeh Khalili, Aida Malek Mahdavi
Summary: This paper systematically reviewed the existing studies about fenugreek and rheumatoid arthritis (RA) and found that fenugreek has favorable effects in RA, attenuating inflammation, suppressing oxidative stress, and displaying anti-arthritic activity.
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
(2023)
Article
Biochemistry & Molecular Biology
David Sinka, Eniko Doma, Nora Szendi, Jazmin Pall, Dora Kosa, Agota Peto, Palma Feher, Zoltan Ujhelyi, Ferenc Fenyvesi, Judit Varadi, Miklos Vecsernyes, Zsolt Szucs, Sandor Gonda, Zoltan Cziaky, Attila Kiss-Szikszai, Gabor Vasas, Ildiko Bacskay
Summary: Fenugreek is a widely studied spice and herbal medicine with antidiabetic and antioxidant effects. In this study, self-emulsifying drug delivery systems (SEDDS) were formulated to improve the stability and permeability of fenugreek extract. The SEDDS exhibited good stability, enhanced bioavailability, and sustained release of the compounds from capsules.
Article
Plant Sciences
Hessamoddin Solouki, Mohammad Kafi, Jafar Nabati, Mohammad Javad Ahmadi-Lahijani, Ahmad Nezami, Roshanak Shahriary Ahmady
Summary: Seed germination behaviors are influenced by ecological parameters and climate change scenarios. Different temperature levels affect the accuracy of thermal-germination models and germination-rate response of Iranian fenugreek ecotypes. The Mashhad ecotype exhibits stronger germination ability under high temperatures.
JOURNAL OF APPLIED RESEARCH ON MEDICINAL AND AROMATIC PLANTS
(2022)
Article
Pharmacology & Pharmacy
Lina Fayoumi, Mahmoud Khalil, Doaa Ghareeb, Mohammad H. El-Dakdouki
Summary: This study identified the phytochemical constituents of Lebanese rose geranium and assessed its antioxidant, anti-inflammatory, anti-acetylcholinesterase (AChE), cytotoxic, and anti-haemolytic properties. The ethanolic leaves extract showed the highest content of total phenolics, total flavonoids, and condensed tannins, as well as superior antioxidant potential. The chloroform extracts exhibited good anti-inflammatory activity, while the ethanol and ethyl acetate extracts showed the highest anti-AChE activity. The most potent cytotoxic activity against HCT 116 colon cancer cells was observed in the chloroform leaves extract.
Article
Neurosciences
Mohammad H. Merii, Manal M. Fardoun, Khalil El Asmar, Mahmoud I. Khalil, Ali H. Eid, Hassan R. Dhaini
Summary: This study investigated the effects of maternal exposure to BPA on the expression of CYP450s in fetal brain. The results showed that BPA significantly decreased the expression of CYP1B1 at GD14 and CYP19A1 at mid- and late-stage development. Nicotine also decreased the expression levels of all examined protein targets, and this suppressive effect was attenuated when combined with BPA.
NEUROTOXICOLOGY AND TERATOLOGY
(2022)
Letter
Dentistry, Oral Surgery & Medicine
John K. Brooks, Julia H. Song, Ahmed S. Sultan
Article
Biochemistry & Molecular Biology
Hany Elsawy, Abdullah M. Alzahrani, Manal Alfwuaires, Ashraf M. Abdel-Moneim, Mahmoud Khalil
Summary: Naringin (NG) has been found to protect against testicular tissue damage caused by methotrexate (MTX), making it a potential candidate therapy for the reproductive toxic impacts of MTX.
Article
Thermodynamics
Shimaa Zahran, Ahmed A. Sultan, Maher Bekheit, Mohamed R. Elmarghany
Summary: This study experimentally and numerically investigated turbulent air flow through a rectangular cross-sectional duct with one corrugated surface. The results showed that the corrugated surface considerably enhanced the heat transfer rate while slightly increasing the pressure drop.
CASE STUDIES IN THERMAL ENGINEERING
(2022)
Article
Dentistry, Oral Surgery & Medicine
John K. Brooks, Arash Rostami, Cindy Q. Zhou, Ahmed S. Sultan
Summary: This article reports a case of a longstanding intraoral spindle cell lipoma that had become increasingly painful during mastication. Timely removal may reduce complications.
Article
Biochemistry & Molecular Biology
Russul M. M. Adnan, Malak Mezher, Alaa M. M. Abdallah, Ramadan Awad, Mahmoud I. I. Khalil
Summary: This study aimed to investigate the effect of Mg doping on the characteristics and antibacterial properties of CuO nanoparticles (NPs). Mg-doped CuO NPs were fabricated by co-precipitation, and characterization techniques including XRD, TEM, EDX, FTIR, and PL were used. The results showed that Mg doping affected the morphology and agglomeration of the NPs, and induced shifts in the Cu-O bond. The undoped and Mg-doped CuO NPs exhibited significant antibacterial capacities against both Gram-positive and Gram-negative bacteria, highlighting their potential as antibacterial agents.
Article
Green & Sustainable Science & Technology
Ahmed Saad Soliman, Ahmed A. Sultan, Mohamed A. Sultan
Summary: This study experimentally and numerically investigated the melting process of paraffin wax in storage capsules of different shapes. The results showed that the shape of the storage capsule and the value of A(mush) greatly influence the melting process of the PCM.
Article
Engineering, Electrical & Electronic
Sultan Ahmad, Mohammed Yousuf Uddin
Summary: The Internet of Things (IoT) plays a significant role in various daily life applications, such as health monitoring, environmental monitoring, vehicle monitoring, crop monitoring, and material science. The proposed method aims to periodically monitor environmental factors by analyzing data collected from sensors and Nano electronics devices. The use of an IoT-dependent smart irrigation system can help achieve optimal resource utilization in precision farming. The proposed system relies on a smarter algorithm that considers sensed data along with weather forecast parameters for effective decision-making.
JOURNAL OF NANOELECTRONICS AND OPTOELECTRONICS
(2023)
Review
Dentistry, Oral Surgery & Medicine
David E. McReynolds, Advan Moorthy, James O'Connor Moneley, Mary Ann Jabra-Rizk, Ahmed S. Sultan
Summary: This interdisciplinary clinical review provides an overview of denture stomatitis, focusing on its etiopathogenesis, clinical features, and management strategies. The review emphasizes the importance of good oral and denture hygiene in preventing the formation of Candida-containing polymicrobial biofilms, which are responsible for this common infectious and inflammatory condition. Treatment of denture stomatitis not only improves oral health but also reduces the risk of associated complications such as aspirational pneumonia and mortality.
JOURNAL OF PROSTHODONTICS-IMPLANT ESTHETIC AND RECONSTRUCTIVE DENTISTRY
(2023)
Review
Neurosciences
MayaN Abou N. Chahla, Mahmoud I. Khalil, Stefano Comai, Lena Brundin, Sophie Erhardt, Gilles J. Guillemin
Summary: Suicide is a global health burden, ranking as the 17th leading cause of death worldwide (1.3%), and the 4th among young people aged 15 to 29. Suicidal behavior is a complex and multifactorial mental health problem, resulting from alterations and dysfunctions in biological pathways and brain mechanisms that are poorly understood and require further investigation. Extensive research has been conducted at various levels to uncover the triggers and develop therapeutic or preventive approaches for suicidal behavior.
Article
Cell Biology
Eman Hefni, Deepak Menon, Tao Ma, Emmanuel B. Asiedu, Ahmed Sultan, Timothy Meiller, Abraham Schneider, Akrit Sodhi, Silvia Montaner
Summary: This study investigated the molecular mechanisms of angiopoietin-like 4 (ANGPTL4) in the growth and dissemination of head and neck squamous cell carcinoma (HNSCC). It was found that ANGPTL4 was upregulated in premalignant cells and HNSCC cell lines, as well as tissue samples from patients with oral dysplasia and HNSCC. Furthermore, ANGPTL4 was found to promote tumor cell migration through its binding to neuropilin1 (NRP1) and subsequent phosphorylation of focal adhesion protein, paxillin (PXN), in a pathway dependent on ABL1 tyrosine kinase. Inhibition of ABL1 or NRP1 expression blocked this pathway and inhibited tumor cell migration.
CELLULAR SIGNALLING
(2023)
Article
Medicine, General & Internal
Mariam Ayed, Anwar Yazdani, Hind Esmaelili, Abdulla Alsaleh, Ahmed Sultan, Esam Alamad, Ali Bander, Hanouf Rawdhan
Summary: The objective of this study was to describe the impact of working during the COVID-19 pandemic on the mental health of resident physicians. The results showed that not being able to work with COVID-19 patients, work affecting study schedules, and loss of off-service training time were associated with higher stress and depression scores. Additionally, anxiety scores were significantly higher in females.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Meeting Abstract
Oncology
Rana Hamed Alneanaey, Nabil Taha, Mohammed Lebda, Aml Hashem, Ahmed Sultan
Article
Genetics & Heredity
Alaa A. Alnafjan, Afrah F. Alkhuriji, Hussah M. Alobaid, Zainb A. Babay, Mahmoud Khalil
Summary: The study investigated the association of FTO rs9939609 and rs1421085 with PCOS in Saudi women. Results showed that the FTO rs9939609 gene variant is significantly associated with PCOS susceptibility, while the rs1421085 variant did not show significant differences between PCOS patients and controls.
EGYPTIAN JOURNAL OF MEDICAL HUMAN GENETICS
(2022)
