Article
Materials Science, Biomaterials
Yangkun Liu, JinChuan Fan, MingQi Lv, Kepeng She, Jiale Sun, Qingqing Lu, Changhao Han, SongTao Ding, Shuang Zhao, GuiXue Wang, YuChan Zhang, GuangChao Zang
Summary: The Ag-AV-SF hydrogel developed in this study demonstrated excellent physical properties, strong antibacterial properties, satisfactory biocompatibility, and significant promoting effects on cell proliferation, migration, and wound healing. It showed great potential in promoting early healing, reconstructing blood vessels networks, and inhibiting scar formation.
REGENERATIVE BIOMATERIALS
(2021)
Review
Polymer Science
Mariana Chelu, Adina Magdalena Musuc, Monica Popa, Jose Calderon Moreno
Summary: This study provides a comprehensive overview of recent advances in aloe vera-based hydrogels for wound healing, including synthesis methods, structural characteristics, properties, and mechanisms of therapeutic agent release. It also highlights the therapeutic effects of aloe vera-based hydrogels on wound healing and their potential for improving outcomes.
Article
Plant Sciences
Sultana Razia, Hyunsung Park, Eunju Shin, Kyu-Suk Shim, Eunae Cho, Min Chol Kang, Sun Yeou Kim
Summary: This study investigates the synergistic effect of a mixture of Aloe vera flower and Aloe gel on cutaneous wound healing and reveals its molecular mechanism targeting microfibril-associated glycoprotein 4 (MFAP4) and its associated signaling pathway. The mixture enhances cell proliferation, migration, and ECM formation in normal human dermal fibroblast (NHDF) cells by increasing the expression of MFAP4. It also activates the ERK and AKT signaling pathways and slightly modifies the cell cycle. In addition, the mixture induces cell migration and suppresses inflammatory cytokines in HaCaT cells. The knockdown of MFAP4 highlights its crucial role in cutaneous wound healing.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Polymer Science
Karen Zulema Meza-Valle, Rosa Alicia Saucedo-Acuna, Karla Lizzette Tovar-Carrillo, Juan Carlos Cuevas-Gonzalez, Erasto Armando Zaragoza-Contreras, Juana Melgoza-Lozano
Summary: The study demonstrates that Aloe vera hydrogel can enhance wound healing speed, reduce the total healing time, and achieve complete wound closure in 15 days. The results confirm the good interaction of the hydrogel with proteins and growth factors, as well as the microstructure and micro-roughness that promote good adhesion to the wound.
Review
Pharmacology & Pharmacy
Sibusiso Alven, Vuyolwethu Khwaza, Opeoluwa O. Oyedeji, Blessing A. Aderibigbe
Summary: Aloe vera, a plant extract rich in essential nutrients, has attracted significant attention in wound management for its positive effects on wound healing process. Most currently used wound dressing materials face challenges such as poor antimicrobial properties and weak mechanical performance, requiring better alternative solutions.
Article
Environmental Sciences
Diaa Massoud, Maged M. A. Fouda, Moustafa Sarhan, Shaimaa Gamal Salama, Heba Saied Khalifa
Summary: The topical application of Aloe gel and/or olive oil has been found to significantly enhance the healing process of diabetic wounds. The combination of Aloe gel and olive oil (AVO) showed the most improvement in healing kinetics compared to separate application of either Aloe gel or olive oil. This study highlights the potential of natural products in promoting the healing of diabetic wounds.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Chemistry, Physical
Aiyah S. Noori, Neean F. Mageed, Nisreen Kh. Abdalameer, Mustafa K. A. Mohammed, Sabah N. Mazhir, Alyaa H. Ali, Nasma A. Jaber, Safa H. Mohammed
Summary: The experiment showed that activating Aloe vera solution could significantly enhance wound healing in albino mice, with the best improvement observed after 7 minutes of activation. The microwave plasma system exhibited high efficiency in extracting Aloe vera solution.
CHEMICAL PHYSICS LETTERS
(2022)
Review
Chemistry, Medicinal
Saeideh Sabbaghzadegan, Haide Golsorkhi, Mohammad Hossein Soltani, Mohammad Kamalinejad, Mohsen Bahrami, Ali Kabir, Majid Dadmehr
Summary: Cardiovascular diseases are the most prevalent causes of morbidity and mortality in both men and women, associated with various risk factors. Aloe vera gel, with its multiple biological activities, has shown beneficial effects on cardiovascular disease risk factors, but further high-quality studies are needed to firmly establish its clinical efficacy.
PHYTOTHERAPY RESEARCH
(2021)
Article
Pharmacology & Pharmacy
Lena Katharina Mueller-Heupt, Nadine Wiesmann, Sofia Schroeder, Yueksel Korkmaz, Nina Vierengel, Jonathan Gross, Rolf Dahm, James Deschner, Till Opatz, Juergen Brieger, Bilal Al-Nawas, Peer W. Kaemmerer
Summary: This study investigated the effect of Aloe vera and Rheum palmatum root on oral wound healing. The results showed that they can promote fibroblast migration and have antimicrobial efficacy against Porphyromonas gingivalis. These compounds could be potential topical treatments for wound healing disorders.
Article
Chemistry, Physical
Kumar Vishven Naveen, Kandasamy Saravanakumar, Anbazhagan Sathiyaseelan, Myeong-Hyeon Wang
Summary: This study reports on the eco-friendly fabrication of Aloe vera-Gum Arabic-silver-nanocomposite with strong antibacterial and anti-biofilm activity. The nanocomposite is non-toxic to cells and promotes wound healing.
COLLOID AND INTERFACE SCIENCE COMMUNICATIONS
(2022)
Article
Food Science & Technology
Ali Ikram, Syed Qasim Raza, Farhan Saeed, Muhammad Afzaal, Haroon Munir, Aftab Ahmed, Muhammad Babar Bin Zahid, Faqir Muhammad Anjum
Summary: The addition of aloe vera gel had significant effects on various properties of yogurt, with decreases in pH, viscosity, fat content, and other values over time, while acidity and syneresis increased. Overall, adding 3% aloe vera to yogurt with 1% fat content was found to be the most effective in terms of both physicochemical and organoleptic characteristics.
FOOD SCIENCE & NUTRITION
(2021)
Review
Materials Science, Multidisciplinary
Nuraina Hanim Mohd Nizam, Nurul Fazita Mohammad Rawi, Sitti Fatimah Mhd Ramle, Azniwati Abd Aziz, C. K. Abdullah, A. Rashedi, Mohamad Haafiz Mohamad Kassim
Summary: The growing consumer awareness of environmentally-friendly products has led to the development of starch-based films as excellent alternatives with biodegradable properties. In addition to being environmentally friendly, these films are also researched and developed for their antimicrobial properties, making them a promising option for active packaging systems.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2021)
Review
Engineering, Environmental
Md. Ibrahim H. Mondal, Joykrisna Saha, Md. Ashadur Rahman
Summary: Aloe vera is an ancient medicinal plant with over 200 biologically-active substances, known for its healing properties and fewer adverse effects compared to other alternative herbal medicines. The key component in Aloe vera leaves is acemannan, a long-chain polymer with immune modulation, antibacterial, antifungal, and antitumor properties. Aloe vera is extensively used in cosmetics, wound healing, and textile composites for various purposes such as tissue engineering, medical textiles, and UV protection textiles.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2021)
Article
Polymer Science
Mariana Chelu, Monica Popa, Emma Adriana Ozon, Jeanina Pandele Cusu, Mihai Anastasescu, Vasile Adrian Surdu, Jose Calderon Moreno, Adina Magdalena Musuc
Summary: The present research focuses on studying the properties of hydrogels made from allantoin, xanthan gum, salicylic acid, and different concentrations of Aloe vera. The evaluation included thermal behavior, chemical structure, morphology, and pharmacotechnical properties of the hydrogels. Results showed that the addition of Aloe vera led to interactions with the hydrogel matrix, and a formulation with 10% Aloe vera concentration was found suitable for biomedical applications.
Article
Pharmacology & Pharmacy
Yongli Hou, Yan Gao, Xiaorui Wang, Yongai Zhang, Jing Li, Haimiao Zhang, Xiujuan Li
Summary: This study aimed to accelerate wound healing in delayed cesarean section patients using alginate-aloe vera/ZnO NPs film plus mupirocin. Results showed faster recovery in the treated group compared to the control, with no allergic reactions reported. The use of this treatment may be a new approach to reduce complications in CS approximation.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Article
Biology
N. Moosanejad, A. Firouzian, S. A. Hashemi, M. Bahari, M. Fazli
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
(2016)
Article
Pediatrics
Hamed Roohanizadeh, Hasan Karami, Seyyed Abbas Hashemi
INTERNATIONAL JOURNAL OF CHILD HEALTH AND NUTRITION
(2019)
Article
Medicine, General & Internal
A. Sharifpour, M. Zahedi, M. D. Khezri, R. Sadeghnezhad, S. A. Hashemi
ARCHIVES OF HELLENIC MEDICINE
(2019)
Article
Medicine, General & Internal
Ali Sharifpour, Mohammad Sazgar, Seyyed Abbas Hashemi, Mohammad Zahedi, Mahdi Abounoori, Reza Sadeghnezhad
PAKISTAN JOURNAL OF MEDICAL & HEALTH SCIENCES
(2019)
Review
Agriculture, Multidisciplinary
Seyyed Abbas Hashemi, Sayeh Ghorbanoghli, Ali Asghar Manouchehri, Mandi Babaei Hatkehlouei
AIMS AGRICULTURE AND FOOD
(2019)
Article
Pathology
Seyyed Abbas Hashemi, Seyed Mohammad Valizadeh, Sanaz Gonoodi, Iradj Maleki
Article
Medicine, General & Internal
Seyyed Abbas Hashemi, Ali Habibi, Sayehghorbanoghli, Seid Hossein Hosseini, Hamed Jafar Pour, Amir Shams Hirian
PAKISTAN JOURNAL OF MEDICAL & HEALTH SCIENCES
(2019)
Review
Medicine, Research & Experimental
Sayeh Ghorbanoghli, Seyyed Abbas Hashemi, Saeed Amirkhanloo, Arash Rezaei Shahmirzadi, Ali Hadian, Niyosha Nazemi, Sara Bybordi, Ashkan Piranviseh, Hamideh Akbari, Sina Nazemi
JOURNAL OF RESEARCH IN MEDICAL AND DENTAL SCIENCE
(2019)
Review
Medicine, Research & Experimental
Seyyed Abbas Hashemi, Sahar Azadeh, Bahram Movahed Nouri, Rezal Alizade Navai
INTERNATIONAL JOURNAL OF MEDICAL RESEARCH & HEALTH SCIENCES
(2017)
Article
Biotechnology & Applied Microbiology
Zoleikha Atarod, Sepideh Mahjouri, Sahar Azadeh, Bahram Movahed Nouri, Seyyed Abbas Hashemi
INTERNATIONAL JOURNAL OF ADVANCED BIOTECHNOLOGY AND RESEARCH
(2017)
Article
Biotechnology & Applied Microbiology
Vahid Avazzadeh, Bahram Movahed Nouri, Sahar Azadeh, Mohammad Ekrahi, Mehran Fazli, Seyyed Abbas Hashemi
INTERNATIONAL JOURNAL OF ADVANCED BIOTECHNOLOGY AND RESEARCH
(2017)
Article
Medicine, General & Internal
Seyyed Abdollah Madani, Seyyed Abbas Hashemi, Mostafa Modanluo
JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION
(2015)
Article
Medicine, General & Internal
Hojjat Derakhshanfar, Farzad Bozorgi, Adel Hosseini, Shamila Noori, Abolfazl Mostafavi, Ali Sharami, Seyyed Abbas Hashemi
ACTA FACULTATIS MEDICAE NAISSENSIS
(2015)
Article
Orthopedics
Masoud ShayestehAzar, Mohammad H. Kariminasab, Majid Sajjadi Saravi, Mahmoud Abedini, Mehran Fazli, Seyyed Abbas Hashemi, Pedram Abdizadeh
ARCHIVES OF BONE AND JOINT SURGERY-ABJS
(2015)
