Article
Acoustics
J. Gutierrez Henares, R. Gutierrez Henares, H. Perry, A. Khalil, B. Thilaganathan
Summary: Objective non-invasive assessment of maternal cardiovascular potential and kinetic energy using PKR and SMII may help distinguish pregnancies affected by specific placental disorders and those exhibiting healthy cardiovascular adaptation to pregnancy. Women with HDP and/or SGA have distinctive PKR and SMII profiles, reflecting low kinetic energy in pregnancies with SGA and high potential energy in pregnancies affected by HDP. Non-invasive assessment of potential and kinetic cardiovascular energy demonstrates high-flow and low-resistance adaptation in uncomplicated pregnancies.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2022)
Article
Obstetrics & Gynecology
Berta Serrano, Erika Bonacina, Carlota Rodo, Pablo Garcia-Manau, Maria Angeles Sanchez-Duran, Maria Pancorbo, Cristina Forcada, Maria Teresa Murcia, Ana Perestelo, Mireia Armengol-Alsina, Manel Mendoza, Elena Carreras
Summary: This study compared the predictive accuracy of the Gaussian algorithm and the FMF algorithm for early-onset pre-eclampsia (PE) and small for gestational age (SGA). The results showed that these two algorithms had similar performances for most outcomes and marker combinations. However, the Gaussian algorithm had significant differences in predicting early-onset PE in certain combinations.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Review
Food Science & Technology
Donghui Huang, Xiaoying Li, Qijun Wu, Chao Ji, Huixu Dai, Hang Li, Qing Chang, Xin Xu, Yuhong Zhao
Summary: This study examined the relationship between dairy consumption during pregnancy and pregnancy complications. Based on the analysis of multiple studies, there seems to be a neutral association between dairy consumption and gestational weight gain, gestational diabetes mellitus, and pre-eclampsia.
JOURNAL OF FUNCTIONAL FOODS
(2023)
Article
Acoustics
N. Sokratous, M. Bednorz, P. Sarli, O. E. Morillo Montes, A. Syngelaki, A. Wright, K. H. Nicolaides
Summary: This study aimed to examine the performance of screening for preterm and term pre-eclampsia (PE) using maternal factors and combinations of maternal serum glycosylated fibronectin (GlyFn), mean arterial pressure (MAP), uterine artery pulsatility index (UtA-PI), and serum placental growth factor (PlGF) during early pregnancy. The findings suggest that GlyFn may be a useful biomarker for screening preterm PE in the first trimester. However, the performance of screening for term PE or gestational hypertension at 11-13 weeks' gestation using any combination of biomarkers is poor. Prospective screening studies are needed to validate the results of this case-control study.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2023)
Article
Acoustics
E. Gibbone, I. Sapantzoglou, M. E. Nunez-Cerrato, A. Wright, K. H. Nicolaides, M. Charakida
Summary: This study aimed to investigate the association between the PSV ratio and maternal cardiovascular function in an unselected population at 19-23 weeks' gestation. It found weak associations between the PSV ratio and most cardiovascular indices in the total population, except for mean arterial pressure. However, in the subgroup that developed PE, a moderately strong association between the PSV ratio and left ventricular mass indexed for body surface area was noted.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Mandy Goldberg, Mary Diaz-Santana, Katie M. O'Brien, Shanshan Zhao, Clarice R. Weinberg, Dale P. Sandler
Summary: This study examined the association between gestational hypertensive disorders and breast cancer in a cohort of women with a family history of breast cancer. The results showed that a history of gestational hypertensive disorder was not associated with breast cancer risk.
Article
Environmental Sciences
Kun Yuan, Feng Sun, Yangchang Zhang, Ying Du, Lizhi Wu, Yang Ge, Zhenyu Zhang, Wangnan Cao, Shengzhi Sun
Summary: A study found that exposure to ambient ozone during pregnancy may be associated with hypertensive disorders in pregnancy. The research in the contiguous United States linked maternal exposure to ozone with the risk of gestational hypertension and eclampsia, showing a significant association. This has important implications for women's health and pregnancy management.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Endocrinology & Metabolism
Jemina Kivela, Heidi Sormunen-Harju, Polina Girchenko, Emilia Huvinen, Beata Stach-Lempinen, Eero Kajantie, Pia M. Villa, Rebecca M. Reynolds, Esa K. Hamalainen, Marius Lahti-Pulkkinen, Katja K. Murtoniemi, Hannele Laivuori, Johan G. Eriksson, Katri Raikkonen, Saila B. Koivusalo
Summary: The study reveals that pregnant women with obesity and pregnancy disorders have similar metabolic impacts, indicating a shared metabolic origin. Furthermore, women with obesity show smaller metabolic changes during pregnancy.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Acoustics
N. Gana, M. Sarno, N. Vieira, A. Wright, M. Charakida, K. H. Nicolaides
Summary: This study aimed to evaluate the potential value of ophthalmic artery Doppler at 11-13 weeks' gestation as a predictive marker for pre-eclampsia (PE) and compare it with other first-trimester biomarkers. The results showed that ophthalmic artery PSV ratio may be helpful in predicting the development of preterm PE. However, larger studies are still needed to validate this finding.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2022)
Article
Neurosciences
Xue-Fei Liu, Jing-Jing Lu, Meng-Die Li, Ying Li, An-Rong Zeng, Jin-Wei Qiang
Summary: A radiomics nomogram based on diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) maps was established to predict pre-eclampsia (PE) from gestational hypertension (GH). The nomogram exhibited good performance in both the training and test cohorts for predicting PE from GH. It can be conveniently used to facilitate treatment decisions for clinicians and patients.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Multidisciplinary Sciences
Agnethe Lund, Cathrine Ebbing, Svein Rasmussen, Elisabeth Qvigstad, Torvid Kiserud, Jorg Kessler
Summary: The study found a correlation between maternal body mass index and gestational weight gain with fetal venous liver flow and birthweight in pregnancies with pre-gestational diabetes mellitus. Overweight and excessive gestational weight gain were associated with higher birthweights in women with pre-gestational diabetes mellitus. Fetal venous liver perfusion seems to be a key determinant for fetal growth and birthweight, modifiable by maternal factors, especially in pregnancies with pre-gestational diabetes mellitus.
Article
Biology
Jieun Kang, Sangwon Hwang, Taesic Lee, Kwangjin Ahn, Dong Min Seo, Seong Jin Choi, Young Uh
Summary: The prediction of pre-eclampsia is important, but current biomarkers face challenges in clinical settings. This study found that incorporating serum creatinine levels and considering renal hyperfiltration significantly improved PE prediction. The developed model is practical and can be easily applied in primary care settings.
Article
Nutrition & Dietetics
Huifeng Shi, Yuanhui Jiang, Pengbo Yuan, Lian Chen, Xiaoli Gong, Yike Yang, Yuanyuan Wang, Hai Jiang, You Li, Mengxing Sun, Yangyu Zhao, Yuan Wei
Summary: This study revealed a non-linear association between vitamin E concentrations in the first trimester and gestational vitamin E change with pre-eclampsia. The findings showed that vitamin E concentrations below 7.3 mg/L and gestational decrease were associated with increased risk of pre-eclampsia.
FRONTIERS IN NUTRITION
(2022)
Review
Obstetrics & Gynecology
Wilfried Gyselaers
Summary: Gestational hypertension and preeclampsia are two main types of hypertensive disorders in pregnancy with different hemodynamic profiles, and blood pressure is determined by intravascular volume load and vascular resistance.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Acoustics
I Sapantzoglou, A. Wright, M. Gallardo Arozena, R. Vallenas Campos, M. Charakida, K. H. Nicolaides
Summary: The study showed that the ophthalmic artery PSV ratio at 19-23 weeks' gestation could be used to predict the development of PE, especially preterm PE. Combining the PSV ratio with other biomarkers improved the accuracy of predicting PE, but larger studies are needed to validate these findings.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2021)