Article
Obstetrics & Gynecology
Maria Stefopoulou, Lotta Herling, Jonas Johnson, Peter Lindgren, Torvid Kiserud, Ganesh Acharya
Summary: This study aimed to establish longitudinal reference intervals for fetal SVC blood flow velocities and pulsatility index during the second half of pregnancy. The results showed that SVC velocities increased with advancing gestation, while the PIV remained stable throughout the second half of pregnancy.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Cardiac & Cardiovascular Systems
William R. Miranda, Patrick S. Kamath, C. Charles Jain, Heidi C. Connolly, Alexander C. Egbe
Summary: This study found that APRI and Fib-4 scores were positively correlated with resting and exercise Fontan pressure and PAWP, and negatively correlated with arterial O2 saturation. These results support the role of hepatic venous hypertension and reduced oxygen supply in patients with FALD.
CANADIAN JOURNAL OF CARDIOLOGY
(2023)
Article
Obstetrics & Gynecology
Greggory R. DeVore, Bardo Polanco
Summary: This study evaluated the maternal cardiac function using a cardiac probe and Doppler ultrasound technology. The results showed the changes in cardiac blood flow and condition, providing a basis for clinicians to select appropriate hypertension medication.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Article
Obstetrics & Gynecology
Greggory R. Devore, Bardo Polanco
Summary: This study demonstrates that evaluation of maternal cardiac function using a cardiac probe can provide important information about left ventricular preload, afterload, contractility, and blood flow in pregnant women. The findings show that these measurements vary throughout gestation and can assist clinicians in selecting appropriate treatment options in early pregnancy.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Article
Acoustics
P. I. Cavoretto, N. Salmeri, M. Candiani, A. Farina
Summary: This study provides gestational-age specific reference ranges for mean uterine artery pulsatility index (UtA-PI) based on longitudinal data assessment throughout pregnancy. The results show a progressive non-linear decrease in UtA-PI during pregnancy, and the new reference ranges may have better performance in screening for placenta-associated diseases and evaluating the potential risk for pregnancy-induced hypertension and/or small-for-gestational age.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Vita Zidere, Trisha V. Vigneswaran, Argyro Syngelaki, Marietta Charakida, Lindsey D. Allan, Kypros H. Nicolaides, John M. Simpson, Ranjit Akolekar
Summary: This study reports prospective assessment of a large number of normal fetuses with Doppler blood flow measurements, establishing reference ranges for fetal cardiac Doppler measurements and heart rate, which may be valuable in clinical practice.
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2021)
Article
Neurosciences
Francesco Fisicaro, Giuseppe Lanza, Carmela Cinzia D'Agate, Manuela Pennisi, Mariagiovanna Cantone, Giovanni Pennisi, Marios Hadjivassiliou, Rita Bella
Summary: This study explored the cerebral hemodynamics in patients with celiac disease (CD) and found that the resistivity and pulsatility indices in the basilar artery were significantly higher in patients compared to healthy controls. These indices were also negatively correlated with cognitive assessment scores, potentially expanding the spectrum of pathomechanisms underlying neuroceliac disease.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Review
Medicine, General & Internal
Moira Barbieri, Giulia Zamagni, Ilaria Fantasia, Lorenzo Monasta, Leila Lo Bello, Mariachiara Quadrifoglio, Giuseppe Ricci, Gianpaolo Maso, Monica Piccoli, Daniela Denis Di Martino, Enrico Mario Ferrazzi, Tamara Stampalija
Summary: The objectives of this study were to review the available umbilical vein blood flow volume (UV-Q) reference ranges in uncomplicated pregnancies and compare them with UV-Q values obtained from a local cohort. Literature in English was reviewed according to PRISMA guidelines. Original articles were grouped based on UV sampling sites and formulae used to compute UV-Q. The UV-Q values were derived from formulae or tables presented by authors. A prospective observational study of uncomplicated singleton pregnancies was conducted to compare UV-Q with the systematic review results. Overall, there was a substantial heterogeneity in reported UV-Q central values, but values overlapped when using the same sampling methodology and formulae. The study suggests that UV-Q assessment is accurate and reproducible when adhering to the same methodology, encouraging further investigation on clinical applications.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Neurosciences
Chun Li, Jihong Meng, Baoxin Xu, Xiaodong Li, Miaomiao Li, Xue Du, Shaoyi Li, Weining Ma
Summary: This study aimed to investigate the relationship between CT angiography (CTA) manifestations in the anterior cerebral artery a1 segment (A1) and hemodynamics in patients with internal carotid artery stenosis (ICAS). A total of 97 cases were analyzed, and the degree of ICAS and symmetry of A1 were evaluated using CTA examination, while hemodynamic indexes were measured using transcranial Doppler (TCD). The study found that the presentation of A1 on the side of ICAS reflects the overall changes in intracranial hemodynamics, and a combination of TCD and CTA examination of A1 can help determine the location and degree of ICAS.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Pediatrics
Maria Stefopoulou, Jonas Johnson, Lotta Herling, Peter Lindgren, Torvid Kiserud, Ganesh Acharya
Summary: This study aimed to investigate the fetal hemodynamic development during the second half of physiological pregnancies, and found that fetal Q(SVC) significantly increases with gestation, constituting roughly 10% of the fetal CCO at any time during the second half of pregnancy.
FRONTIERS IN PEDIATRICS
(2021)
Article
Oncology
Mingyue Wu, Yi Lin, Fang Lei, Yujing Yang, Le Yu, Xueling Liu
Summary: Color Doppler ultrasound is a valuable tool in detecting abnormal blood flow in fetal arteries, providing clinicians with important information to guide subsequent diagnosis and treatment plans.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ziguang Yan, Guochen Niu, Weiping Sun, Junmei Li, Min Yang
Summary: This retrospective cohort study aimed to investigate the changes in cerebral hemodynamics in the early stage following carotid artery stenting (CAS). The study found that the ipsilateral middle cerebral artery (MCA) peak systolic velocity (PSV) and pulsatility index (PI) significantly increased at 1 hour and 3 hours following CAS, particularly in patients with severe stenosis.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Biophysics
Zhongyou Li, Yu Chen, Xiaoxi Zeng, Salerno Stephen, Yi Li, Huafeng Li, Lihua Dong, Teng He, Shihong Zhang, Pei Yang, Wentao Jiang, Haidong Fan
Summary: The study found that there was no significant difference in blood loss or preoperative indicators between patients treated with internal iliac artery balloon occlusion (IIABO) for postpartum hemorrhage caused by pernicious placenta previa (PPP) and the control group. Simulation results revealed that collateral circulation and reversed flow in uterine venules contributed to the ineffectiveness of IIABO treatment.
JOURNAL OF BIOMECHANICS
(2021)
Article
Oncology
Ran Hui, Zhe Li, Zongjie Liu, Xiuping Liu, Heping Deng
Summary: Color Doppler ultrasonography (CDUS) is clinically valuable in measuring the hemodynamics of portal and splenic veins in patients with liver cirrhosis (LC), and can be used to predict the degrees of hepatic injuries and esophageal varices.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2021)
Article
Acoustics
Matthias Barral, Cynthia Pimpie, Rachid Kaci, Iman Al-Dybiat, Massoud Mirshahi, Marc Pocard, Philippe Bonnin
Summary: This study aimed to evaluate the performance of Doppler ultrasound in assessing tumor response in female mice with ovarian peritoneal carcinomatosis. Mice treated with carboplatin showed significant improvements in weight, tumor burden, and blood flow velocity compared to untreated mice, while those treated with bevacizumab did not show significant differences. Doppler ultrasound provides a non-invasive method to assess the effects of anticancer therapy in ovarian peritoneal carcinomatosis-induced mice.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2021)
Article
Acoustics
Bronacha Mylrea-Foley, Hans Wolf, Tamara Stampalija, Christoph Lees
ULTRASCHALL IN DER MEDIZIN
(2023)
Article
Obstetrics & Gynecology
Tamara Stampalija, Hans Wolf, Bronacha Mylrea-Foley, Neil Marlow, Katie J. Stephens, Caroline J. Shaw, Christoph C. Lees
Summary: This study investigated the relationship between fetal growth velocity and signs of cerebral blood flow redistribution in fetuses at risk of fetal growth restriction. It found that reduced growth velocity is associated with an increased risk of adverse perinatal outcome, regardless of signs of cerebral blood flow redistribution.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Article
Nutrition & Dietetics
Kathryn V. Dalrymple, Christina Vogel, Keith M. Godfrey, Janis Baird, Mark A. Hanson, Cyrus Cooper, Hazel M. Inskip, Sarah R. Crozier
Summary: There is a growing interest in modeling longitudinal dietary data to identify subgroups with similar trajectories. This paper compares two latent class methods, group-based trajectory modeling (GBTM) and growth mixture modeling (GMM), to analyze dietary data from a longitudinal study. Both methods suggest that five classes are optimal, with strong correlation between class assignments. Results show stable dietary trajectories with varying levels of quality. GBTM is recommended as it is less computationally intensive, but results can be confirmed using GMM.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Acoustics
C. Ebbing, S. Rasmussen, J. Kessler, D. Moster
Summary: This study found that abnormalities of the umbilical cord or placenta are associated with cerebral palsy (CP), regardless of gestational age or sex of the child.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2023)
Article
Nutrition & Dietetics
Maryann Regina Rolands, Jia Ying Toh, Ray Sugianto, Wen Lun Yuan, Yung Seng Lee, Kok Hian Tan, Fabian Yap, Keith M. Godfrey, Johan G. Eriksson, Yap-Seng Chong, Klazine Van der Horst, Mary Foong-Fong Chong
Summary: The study aims to develop and evaluate a dietary quality index for preschool-aged children in Singapore. The results show that the diet quality of preschool-aged children is generally low, with some excessive intake. Children with mothers of Malay ethnicity, low income, low education level, and shared primary caregiver responsibilities tend to have lower DQI-5 scores.
JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS
(2023)
Review
Pediatrics
Kiran Meka, Chandni M. Jacob, Neena Modi, Flavia Bustreo, Gian Carlo Di Renzo, Ariadne Malamitsi-Puchner, Despina Briana, Domenico G. Iaia, Helga Fogstad, Jagannadha P. Tamvada, Ivan Ochoa Moreno, Mark Hanson
Summary: This study discusses the implications of maternal, newborn, child and adolescent health (MNCAH) on gross domestic product (GDP), and suggests that unremunerated work largely conducted by women should be included in GDP due to its positive impact on future health and prosperity, while industries that harm health should be excluded. In light of the current challenges from COVID, climate change, and conflict, there is a need to redefine economic progress with equitable models and metrics that consider the societal value of activities improving MNCAH in the short, medium, and long term.
Editorial Material
Obstetrics & Gynecology
Torvid Kiserud
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Gastroenterology & Hepatology
Phillip E. E. Melton, M. A. Burton, K. A. Lillycrop, K. M. Godfrey, S. Rauschert, D. Anderson, G. C. Burdge, T. A. Mori, L. J. Beilin, O. T. Ayonrinde, J. M. Craig, J. K. Olynyk, J. D. Holbrook, C. E. Pennell, W. H. Oddy, E. K. Moses, L. A. Adams, R. C. Huang
Summary: Through DNA methylation epigenome-wide association study, we identified novel DNA methylation loci associated with NAFLD and serum liver biochemistry markers during adolescence, implicating putative dmCpG/gene regulatory pathways and providing insights for future mechanistic studies.
HEPATOLOGY INTERNATIONAL
(2023)
Article
Psychiatry
Jian Huang, Ai Peng Tan, Evelyn Law, Keith M. Godfrey, Anqi Qiu, Lourdes Mary Daniel, Marielle Fortier, Kok Hian Tan, Jerry Kok Yen Chan, David Cameron-Smith, Yap Seng Chong, Shiao-Yng Chan, Johan G. Eriksson, Michael J. Meaney, Jonathan Huang
Summary: This study found that higher levels of certain nutrient-related biomarkers in maternal preconception blood were associated with an increased risk of behavioral problems in infants. The study also found that an increase in preconception thiamine levels was associated with higher CBCL scores and a lower right subthalamic nucleus ODI.
TRANSLATIONAL PSYCHIATRY
(2023)
Article
Nutrition & Dietetics
Soo Min Han, Surabhi Devaraj, Jose G. B. Derraik, Mark H. Vickers, Fang Huang, Stephane Dubascoux, Keith M. Godfrey, Shiao-Yng Chan, Wei Wei Pang, Sagar K. Thakkar, Wayne S. Cutfield
Summary: During pregnancy and lactation, zinc supplementation can increase the zinc concentrations in human milk. This study found that a micronutrient-containing supplement including zinc increased the zinc concentrations in human milk, while having no effect on other mineral concentrations. Further studies are needed to understand the associations between zinc and other minerals in human milk and their impact on offspring outcomes.
FRONTIERS IN NUTRITION
(2023)
Article
Obstetrics & Gynecology
D. A. J. M. Schoenaker, J. Stephenson, H. Smith, K. Thurland, H. Duncan, K. M. Godfrey, M. Barker, C. Singh, N. A. Alwan
Summary: This study presents the first national-level report on the state of women's preconception health in England. It found that certain preconception health issues, such as smoking, lack of folic acid supplementation, and previous pregnancy loss, have a high prevalence among women in England. Inequalities in these health issues were observed based on age, ethnicity, and area-based deprivation level. The study suggests the need for improved strategies to address women's preconception health and reduce socio-demographic inequalities.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Letter
Allergy
Zhao Xiang Choa, Gaik Chin Yap, Ruochen Du, Evelyn Xiu Ling Loo, Anne Eng Neo Goh, Oon Hoe Teoh, Hugo P. S. Van Bever, Lynette Pei-Chi Shek, Bee Wah Lee, Kok Hian Tan, Keith M. Godfrey, Johan Gunnar Eriksson, Yap Seng Chong, Shiao Yng Chan, Elizabeth Huiwen Tham
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2023)
Review
Family Studies
Sharon James, Jessica E. Moulton, Anisa Assifi, Jessica Botfield, Kirsten Black, Mark Hanson, Danielle Mazza
Summary: Engaging in lifestyle risk reduction during the interconception period can help reduce adverse outcomes, but there are challenges such as information needs, managing competing priorities, physical and mental health, self-perception and motivation, access to services and professional support, and family and peer networks.
BMJ SEXUAL & REPRODUCTIVE HEALTH
(2023)
Review
Pediatrics
Ariadne Malamitsi-Puchner, Laura Addati, Guony Bjork Eydal, Despina D. D. Briana, Flavia Bustreo, Gian Carlo Di Renzo, Margaret O'Brien, Mark Hanson, Neena Modi
Summary: Cohesive families and stimulating environments with caregiver attachment are crucial for a child's growth. Parental involvement in daily activities like breastfeeding, playing, reading, and storytelling supports early development. Universally accessible and equitable parental leave addresses the challenge of balancing child well-being, career, and gender equality for parents.
Article
Obstetrics & Gynecology
Eirik Nestaas, Lisa Bjarko, Torvid Kiserud, Guttorm Haugen, Drude Fugelseth
Summary: The aim of the study was to assess heart function in FGR neonates during the first three days after birth using echocardiography. The results showed that late-FGR neonates had reduced left diastolic function compared to controls, while there was no significant difference in heart function between early-FGR and late-FGR neonates.
EARLY HUMAN DEVELOPMENT
(2023)