Article
Public, Environmental & Occupational Health
Faisal Alsheddi, Tabish Humayun, Manar Alsaffar, Yvonne Suzette Aldecoa, Wafa H. Alshammari, Fayez Z. Aldalbehi, Hind Alanazi, Mohammed Alqahtani, Aiman El-Saed, Abdulmajid M. Almutairi, Khalid H. Alanazi
Summary: This study aimed to present the current rates of healthcare-associated infections (HAIs) and device utilization ratios (DUR) among Saudi Ministry of Health (MOH) hospitals. The results showed the rates of various infections and device utilization ratios, which can serve as a national benchmark for MOH hospitals and a regional benchmark for similar hospitals in the region.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2023)
Article
Public, Environmental & Occupational Health
M. J. Lydeamore, B. G. Mitchell, T. Bucknall, A. C. Cheng, P. L. Russo, A. J. Stewardson
Summary: This study estimates the burden of healthcare associated infections (HAIs) in Australian public hospitals using a standard international framework. The results show that there are approximately 170,574 HAIs occurring in adults admitted to public hospitals in Australia annually, resulting in 7583 deaths. Hospital acquired pneumonia is the most frequent HAI, followed by surgical site infections and urinary tract infections. The study highlights the high burden of HAIs in Australia and the need for continued investment in prevention efforts.
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2022)
Article
Immunology
Tim Du, Kelly B. Choi, Anada Silva, George R. Golding, Linda Pelude, Romeo Hizon, Ghada N. Al-Rawahi, James Brooks, Blanda Chow, Jun C. Collet, Jeannette L. Comeau, Ian Davis, Gerald A. Evans, Charles Frenette, Guanghong Han, Jennie Johnstone, Pamela Kibsey, Kevin C. Katz, Joanne M. Langley, Bonita E. Lee, Yves Longtin, Dominik Mertz, Jessica Minion, Michelle Science, Jocelyn A. Srigley, Paula Stagg, Kathryn N. Suh, Nisha Thampi, Alice Wong, Susy S. Hota
Summary: We investigated the epidemiology and molecular characteristics of healthcare-associated and community-associated Clostridioides difficile infection (CDI) in adult patients in Canadian hospitals. Our study found higher mortality rate associated with healthcare-associated CDI, and a decrease in both healthcare-associated and community-associated CDI rates from 2015 to 2019. Certain ribotypes were more commonly associated with CDI-related deaths.
EMERGING INFECTIOUS DISEASES
(2022)
Article
Immunology
Brady Page, Michael Klompas, Christina Chan, Michael R. Filbin, Sayon Dutta, Dustin S. McEvoy, Roger Clark, Matthew Leibowitz, Chanu Rhee
Summary: The CDC's hospital-onset Adult Sepsis Event (HO-ASE) definition can detect many serious nosocomial infections that are missed by currently reportable HAIs. Surveillance for HO-ASE could increase efficiency and clinical significance of monitoring while also identifying new targets for prevention.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Medicine, General & Internal
Alexandre Baudet, Nelly Agrinier, Alexandre Charmillon, Celine Pulcini, Alain Lozniewski, Nejla Aissa, Julie Lizon, Nathalie Thilly, Beatrice Demore, Arnaud Florentin
Summary: This study aims to evaluate the impact of implementing a computerised-decision support system (CDSS) and electronic surveillance software (ESS) on antibiotic use in adult inpatients. The evaluation will include factors such as prescription rate, safety, physician satisfaction, and cost. This study is of great importance for addressing antibiotic resistance.
Article
Obstetrics & Gynecology
Ralciane P. Menezes, Savia G. O. Melo, Murilo B. Oliveira, Felipe F. Silva, Priscila G. Alves, Meliza A. S. Bessa, Nagela B. S. Silva, Lucio B. Araujo, Mario P. A. Penatti, Reginaldo S. Pedroso, Vania O. S. Abdallah, Denise V. D. B. Roder
Summary: The study found an increase in infection rates in the NICU in 2015 and 2016, with a higher mortality rate for fungal infections compared to bacterial infections. The use of invasive devices and length of hospital stay were associated with bacterial and fungal infections.
EARLY HUMAN DEVELOPMENT
(2021)
Article
Public, Environmental & Occupational Health
Janneke D. M. Verberk, Tjallie I. I. van der Kooi, Nynke A. Kampstra, Naomi Reimes, Stephanie M. van Rooden, Titia E. M. Hopmans, Suzanne E. Geerlings, Sabine C. de Greeff
Summary: During the COVID-19 pandemic, the number of healthcare-associated infections (HAIs) increased in Dutch hospitals, particularly for ventilator-associated pneumonia (VAP), gastro-intestinal infections (GIs), and central nervous system (CNS) infections. However, no significant changes were observed in surgical site infections (SSIs), except for a decrease after colorectal surgeries. The incidence of catheter-related bloodstream infections (CRBSIs) was also significantly higher during the pandemic, especially in both COVID-19 and non-COVID-19 patients in the intensive care unit (ICU).
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2023)
Article
Public, Environmental & Occupational Health
Henrietta Smith, Jennifer Watkins, Melissa Otis, Joan N. Hebden, Marc-Oliver Wright
Summary: This case study aims to promote standardized application of NHSN HAI surveillance definitions and encourage accurate determination of HAI events among Infection Preventionists (IPs).
AMERICAN JOURNAL OF INFECTION CONTROL
(2022)
Article
Infectious Diseases
Stephanie M. van Rooden, Olov Aspevall, Elena Carrara, Sophie Gubbels, Anders Johansson, Jean-Christophe Lucet, Siddharth Mookerjee, Zaira R. Palacios-Baena, Elisabeth Presterl, Evelina Tacconelli, Mohamed Abbas, Michael Behnke, Petra Gastmeier, Maaike S. M. van Mourik
Summary: Strict governance is essential in surveillance networks, especially when manual decisions are replaced by algorithms and routine-care data is reused. Key considerations for AS networks include participation and inclusion, trust in data quality, accountability, and transparency. Involvement of stakeholders and legal specialists early in AS network development is crucial for endorsement and compliance.
CLINICAL MICROBIOLOGY AND INFECTION
(2021)
Article
Infectious Diseases
Michael Behnke, John Karlsson Valik, Sophie Gubbels, Daniel Teixeira, Brian Kristensen, Mohamed Abbas, Stephanie M. van Rooden, Petra Gastmeier, Maaike S. M. van Mourik
Summary: This document, published in 2021 by the European Society of Clinical Microbiology and Infectious Diseases on behalf of Elsevier Ltd, provides an overview of implementing an automated surveillance system for Healthcare-associated infections (HAI) in a clinical environment.
Written by a task force within the PRAISE network, it offers detailed guidance on key e-health aspects, data storage and structure, IT infrastructure organization, data standardization, interoperability, algorithms, and technical aspects of accessing, storing, and sharing healthcare data for HAI surveillance.
With the support of this document, along with the PRAISE roadmap and governance documents, readers will have comprehensive guidance on implementing large-scale automated surveillance in a healthcare network.
CLINICAL MICROBIOLOGY AND INFECTION
(2021)
Article
Public, Environmental & Occupational Health
Mohamed Ali Daw, Mahamat Hassabarassoul Mahamat, Said Emhamed Wareg, Abdallah H. El-Bouzedi, Mohamed Omar Ahmed
Summary: Healthcare-associated infections are a major issue in Libyan national teaching hospitals, with a prevalence of 13.7%. Surgical site infection is the most common, requiring interventions such as new antimicrobial regimens and admission to intensive care for a significant portion of patients.
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2023)
Article
Public, Environmental & Occupational Health
G. E. Yamaguto, F. Zhen, M. M. Moreira, B. M. Montesanti, S. M. Raboni
Summary: This study evaluated hospital-acquired infections caused by respiratory viruses over six years, finding that in immunosuppressed patients, hematologic neoplasia was the main comorbidity, while prematurity was the most prevalent comorbidity in non-immunosuppressed patients. The results indicated that the circulation of CRVs in the hospital environment is frequent, highlighting the need for enhanced preventive measures in healthcare settings.
JOURNAL OF HOSPITAL INFECTION
(2022)
Article
Public, Environmental & Occupational Health
Mustafa Gokhan Gozel, Can Huseyin Hekimoglu, Emine Yildirim Gozel, Esen Batir, Mary-Louise Mclaws, Emine Alp Mese
Summary: The introduction of a national infection control program in Turkey significantly reduced the prevalence of 3 major device-associated healthcare associated infections from 2008 to 2017. Rates for DA-HAIs declined significantly in hospitals of different bed capacities and geographic locations, with all regions showing improvement by 2017.
AMERICAN JOURNAL OF INFECTION CONTROL
(2021)
Article
Public, Environmental & Occupational Health
J. D. M. Verberk, S. J. S. Aghdassi, M. Abbas, P. Naucler, S. Gubbels, N. Maldonado, Z. R. Palacios-Baena, A. F. Johansson, P. Gastmeier, M. Behnke, S. M. van Rooden, M. S. M. van Mourik
Summary: This study describes the design and implementation of AS systems in Europe, highlighting differences in methods, data sources, and targeted HAIs. AS systems can reduce workload for hospital staff, but implementation barriers include strict data security regulations and the establishment of information technology infrastructure.
JOURNAL OF HOSPITAL INFECTION
(2022)
Article
Public, Environmental & Occupational Health
S. D. van der Werff, E. Thiman, H. Tanushi, J. K. Valik, A. Henriksson, M. Ul Alam, H. Dalianis, A. Ternhag, P. Naucler
Summary: The study aimed to develop and validate a fully automated HA-UTI surveillance algorithm based on electronic health record data. Algorithms 4 and 5, which analyzed free-text medical notes, performed well for HA-UTI surveillance with good sensitivity and specificity.
JOURNAL OF HOSPITAL INFECTION
(2021)
Review
Infectious Diseases
Kelly A. Cairns, Matthew D. M. Rawlins, Sean D. Unwin, Fiona F. Doukas, Rosemary Burke, Erica Tong, Andrew J. Henderson, Allen C. Cheng
Summary: Antimicrobial stewardship is well established in Australian hospitals, but the implementation of electronic medical records (EMR) has been slow. EMR implementation has the potential to positively impact AMS teams through more efficient workflows and expanded activities, but there are inevitable limitations that must be considered.
INFECTIOUS DISEASES AND THERAPY
(2021)
Article
Nursing
Claire L. Crossfield, Tracey K. Bucknall, Philip L. Russo
Summary: Commencing EN on time and meeting target volumes remains challenging in the ICU patient, mainly due to barriers such as airway management, procedural requirements, and delayed dietitian review for prescribed hourly rate initiation. Interdisciplinary interventions are needed to address these issues and provide optimal nutrition delivery.
NURSING IN CRITICAL CARE
(2022)
Article
Medicine, General & Internal
Louisa G. Gordon, Thomas M. Elliott, Brian Forde, Brett Mitchell, Philip L. Russo, David L. Paterson, Patrick N. A. Harris
Summary: This study aimed to predict the cost and health effects of routine use of whole-genome sequencing (WGS) compared with standard care for bacterial pathogens. By analyzing data from 27 hospitals in Queensland, Australia, the study found that WGS surveillance could prevent a substantial number of hospital patients from being infected with multidrug-resistant organisms, leading to cost savings and reduced mortality. Primary prevention through routine use of WGS is recommended as an investment priority for controlling serious hospital-associated infections.
Editorial Material
Medicine, General & Internal
Christopher C. Blyth, Katie L. Flanagan, Robyn A. Gibbs, Nigel W. Crawford, Allen C. Cheng
MEDICAL JOURNAL OF AUSTRALIA
(2021)
Editorial Material
Medicine, General & Internal
Cassie Nesbitt, Louise Rath, Michael Zhong, Allen C. Cheng, Helmut Butzkueven, Robb Wesselingh, Olga Skibina, Mastura Monif, Wei Yeh, Julia M. L. Brotherton, Stephen Reddel, Anneke Van der Walt
MEDICAL JOURNAL OF AUSTRALIA
(2021)
Editorial Material
Medicine, General & Internal
Samantha J. Carlson, Christopher C. Blyth, Frank H. Beard, Alexandra J. Hendry, Allen C. Cheng, Helen E. Quinn, Julie Leask, Kristine Macartney
MEDICAL JOURNAL OF AUSTRALIA
(2021)
Article
Microbiology
Ryan J. Farr, Christina L. Rootes, Louise C. Rowntree, Thi H. O. Nguyen, Luca Hensen, Lukasz Kedzierski, Allen C. Cheng, Katherine Kedzierska, Gough G. Au, Glenn A. Marsh, Seshadri S. Vasan, Chwan Hong Foo, Christopher Cowled, Cameron R. Stewart
Summary: This study analyzed the host miRNA response to COVID-19 and identified a three-miRNA signature that can independently classify COVID-19 cases with high accuracy. The findings suggest that miRNA profiling could potentially improve COVID-19 detection and patient management.
Article
Pediatrics
Ryan Lucas, Peta Dennington, Erica Wood, Kevin J. Murray, Allen Cheng, David Burgner, Davinder Singh-Grewal
Summary: The diagnosis and hospitalization rates of Kawasaki disease (KD) have increased in the 0-4 year age group in Australia over the past 25 years. This rise may reflect a true increase in disease incidence, increasing recognition, or overdiagnosis. Further research is needed to determine the cause of these trends.
JOURNAL OF PAEDIATRICS AND CHILD HEALTH
(2022)
Article
Psychology, Multidisciplinary
Simon T. van Baal, Lukasz Walasek, Daniela Karanfilovska, Allen C. Cheng, Jakob Hohwy
Summary: This study examines the impact of different government communication strategies on people's attitudes towards staying home or going out during the COVID-19 pandemic. It also investigates how individuals perceive and process the risk of viral transmission in different scenarios. The results suggest that the level of risk and communication framings play a significant role in shaping attitudes towards going out. Additionally, age and gender were found to be associated with permissive attitudes. These findings suggest the importance of employing imperative communication strategies for increasing compliance with staying home.
BRITISH JOURNAL OF PSYCHOLOGY
(2022)
Review
Health Care Sciences & Services
Elizabeth Korevaar, Amalia Karahalios, Simon L. Turner, Andrew B. Forbes, Monica Taljaard, Allen C. Cheng, Jeremy M. Grimshaw, Lisa Bero, Joanne E. McKenzie
Summary: This study aimed to examine the statistical approaches, methods, and completeness of reporting in reviews that meta-analyze results from interrupted time series (ITS). The results showed that although most reviews used two-stage meta-analysis and fitted random effects models, reporting of the statistical methods and ITS characteristics was often incomplete. The study suggests that improvement is needed in the conduct and reporting of these reviews.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2022)
Editorial Material
Medicine, General & Internal
Allen C. Cheng, Jim P. Buttery
MEDICAL JOURNAL OF AUSTRALIA
(2022)
Article
Medicine, General & Internal
Husna Begum, Ary S. Neto, Patricia Alliegro, Tessa Broadley, Tony Trapani, Lewis T. Campbell, Allen C. Cheng, Winston Cheung, D. James Cooper, Simon J. Erickson, Craig J. French, Edward Litton, Richard McAllister, Alistair Nichol, Annamaria Palermo, Mark P. Plummer, Hannah Rotherham, Mahesh Ramanan, Benjamin Reddi, Claire Reynolds, Steven A. R. Webb, Andrew A. Udy, Aidan Burrell
Summary: This study compared the demographic characteristics, treatments, and outcomes of patients admitted to intensive care units (ICUs) with COVID-19 during different waves of the pandemic in Australia. The results showed that the characteristics and treatments of patients admitted during the third wave differed from the first two waves. Adjusted in-hospital mortality was highest during the third wave.
MEDICAL JOURNAL OF AUSTRALIA
(2022)
Editorial Material
Medicine, General & Internal
Sarah Allen, Celia M. Cooper, Ajay Taranath, Allen C. Cheng, Philip N. Britton
MEDICAL JOURNAL OF AUSTRALIA
(2023)
Article
Immunology
Bette Liu, Sandrine Stepien, Jiahui Qian, Heather Gidding, Katrina Nicolopoulos, Janaki Amin, Allen Cheng, Kristine Macartney
Summary: This study compared the effectiveness of different COVID-19 vaccines. The results showed that the BNT162b2 mRNA vaccine had higher effectiveness in preventing primary infections compared to mRNA-1273, ChAdOx-1 nCov-19, and NVX-CoV2373. For booster doses, the BNT162b2 mRNA vaccine also showed good effectiveness.
Article
Health Policy & Services
Nguyen Quynh Anh, Nicholas Graves, Michael Dunne, Nguyen Thanh Huong
Summary: The study found that implementing intervention level B in Chi Linh for adolescents was highly cost effective compared to level A, and implementing intervention level C compared to level B was also cost-effective.
INTERNATIONAL JOURNAL OF HEALTHCARE MANAGEMENT
(2021)