A Novel Matrine Derivative WM130 Inhibits Activation of Hepatic Stellate Cells and Attenuates Dimethylnitrosamine-Induced Liver Fibrosis in Rats

β, β-Dimethylacrylshikonin induces mitochondria-dependent apoptosis of human lung adenocarcinoma cells in vitro via p38 pathway activation

(2014) Hai-bing Wang et al.   ACTA PHARMACOLOGICA SINICA

Melittin Inhibits TGF-β-Induced Pro-Fibrotic Gene Expression Through the Suppression of the TGFβRII-Smad, ERK1/2 and JNK-Mediated Signaling Pathway

(2014) Su-Hyun Park et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Inhibitory effects of capsaicin on hepatic stellate cells and liver fibrosis

(2014) Fu-Xiang Yu et al.   Biochemistry and Cell Biology

Effects of β-sitosterol derived from Artemisia capillaris on the activated human hepatic stellate cells and dimethylnitrosamine-induced mouse liver fibrosis

(2014) Ki-Suk Kim et al.   BMC Complementary and Alternative Medicine

Sauchinone attenuates liver fibrosis and hepatic stellate cell activation through TGF-β/Smad signaling pathway

(2014) Ju-Hee Lee et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Toll like receptor 2 knock-out attenuates carbon tetrachloride (CCl4)-induced liver fibrosis by downregulating MAPK and NF-κB signaling pathways

(2014) Lingling Ji et al.   FEBS LETTERS

Bioactive compound reveals a novel function for ribosomal protein S5 in hepatic stellate cell activation and hepatic fibrosis

(2014) Wei-Heng Xu et al.   HEPATOLOGY

Diethylcarbamazine Reduces Chronic Inflammation and Fibrosis in Carbon Tetrachloride- (CCl4-) Induced Liver Injury in Mice

(2014) Sura Wanessa Santos Rocha et al.   MEDIATORS OF INFLAMMATION

Caffeine Inhibits the Activation of Hepatic Stellate Cells Induced by Acetaldehyde via Adenosine A2A Receptor Mediated by the cAMP/PKA/SRC/ERK1/2/P38 MAPK Signal Pathway

(2014) He Wang et al.   PLoS One

Anti-tumor activities of matrine and oxymatrine: literature review

(2014) Yan Liu et al.   TUMOR BIOLOGY

Effect of matrine on transforming growth factor β1 and hepatocyte growth factor in rat liver fibrosis model

(2014) Jian-Lan Yu et al.   Asian Pacific Journal of Tropical Medicine

Neovessel formation promotes liver fibrosis via providing latent transforming growth factor-β

(2013) Kotaro Sakata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways

(2013) Longlong Bao et al.   CANCER LETTERS

Targeted delivery of the RGD-labeled biodegradable polymersomes loaded with the hydrophilic drug oxymatrine on cultured hepatic stellate cells and liver fibrosis in rats

(2013) Jianhong Yang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Involvement of ERK1/2 signaling in proliferation of eight liver cell types during hepatic regeneration in rats

(2013) X.G. Chen et al.   GENETICS AND MOLECULAR RESEARCH

EMT-Induced Stemness and Tumorigenicity Are Fueled by the EGFR/Ras Pathway

(2013) Dominic Chih-Cheng Voon et al.   PLoS One

Observation of Antinociceptive Effects of Oxymatrine and its Effect on Delayed Rectifier K+ Currents (Ik) in PC12 Cells

(2012) Yuyun Wang et al.   NEUROCHEMICAL RESEARCH

Antiinflammatory effects of matrine in LPS-induced acute lung injury in mice

(2011) Bo Zhang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Immune response to extracellular matrix collagen in chronic hepatitis C-induced liver fibrosis

(2011) Brian B. Borg et al.   LIVER TRANSPLANTATION

Synthesis and in vitro inhibitory activity of matrine derivatives towards pro-inflammatory cytokines

(2010) Honggang Hu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Down-regulation of FoxO-dependent c-FLIP expression mediates TRAIL-induced apoptosis in activated hepatic stellate cells

(2009) Soo-Jung Park et al.   CELLULAR SIGNALLING

Hepatocarcinoma cells stimulate the growth, migration and expression of pro-angiogenic genes in human hepatic stellate cells

(2009) Pau Sancho-Bru et al.   LIVER INTERNATIONAL

The roles of MAPKs in disease

(2008) Michael C Lawrence et al.   CELL RESEARCH