Animal Models for the Study of Rodent-Borne Hemorrhagic Fever Viruses: Arenaviruses and Hantaviruses

Laguna Negra Virus Infection Causes Hantavirus Pulmonary Syndrome in Turkish Hamsters (Mesocricetus brandti)

(2015) K. Hardcastle et al.   VETERINARY PATHOLOGY

Old World Hantaviruses in Rodents in New Orleans, Louisiana

(2014) Robert W. Cross et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Animal models of viral hemorrhagic fever

(2014) Darci R. Smith et al.   ANTIVIRAL RESEARCH

A non-randomized multicentre trial of human immune plasma for treatment of hantavirus cardiopulmonary syndrome by ANDV

(2014) Pablo A Vial et al.   ANTIVIRAL THERAPY

Neutrophil Depletion Suppresses Pulmonary Vascular Hyperpermeability and Occurrence of Pulmonary Edema Caused by Hantavirus Infection in C.B-17 SCID Mice

(2014) T. Koma et al.   JOURNAL OF VIROLOGY

Differential Lymphocyte and Antibody Responses in Deer Mice Infected with Sin Nombre Hantavirus or Andes Hantavirus

(2014) T. Schountz et al.   JOURNAL OF VIROLOGY

Delayed Inflammatory and Cell Death Responses Are Associated with Reduced Pathogenicity in Lujo Virus-Infected Cynomolgus Macaques

(2014) Angela L. Rasmussen et al.   JOURNAL OF VIROLOGY

A Substitution in the Transmembrane Region of the Glycoprotein Leads to an Unstable Attenuation of Machupo Virus

(2014) M. Patterson et al.   JOURNAL OF VIROLOGY

Induction of Specific Humoral and Cellular Immune Responses in a Mouse Model following Gene Fusion of HSP70C and Hantaan Virus Gn and S0.7 in an Adenoviral Vector

(2014) Linfeng Cheng et al.   PLoS One

Sequencing, Annotation and Analysis of the Syrian Hamster (Mesocricetus auratus) Transcriptome

(2014) Nicolas Tchitchek et al.   PLoS One

Pathophysiology of hantavirus pulmonary syndrome in rhesus macaques

(2014) D. Safronetz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA vaccine-derived human IgG produced in transchromosomal bovines protect in lethal models of hantavirus pulmonary syndrome

(2014) J. W. Hooper et al.   Science Translational Medicine

Human hantavirus infections: epidemiology, clinical features, pathogenesis and immunology

(2014) T Manigold et al.   SWISS MEDICAL WEEKLY

Pathology of Experimental Machupo Virus Infection, Chicava Strain, in Cynomolgus Macaques (Macaca fascicularis) by Intramuscular and Aerosol Exposure

(2014) T. M. Bell et al.   VETERINARY PATHOLOGY

Long-Term Single-Dose Efficacy of a Vesicular Stomatitis Virus-Based Andes Virus Vaccine in Syrian Hamsters

(2014) Joseph Prescott et al.   Viruses-Basel

Hantavirus Immunology of Rodent Reservoirs: Current Status and Future Directions

(2014) Tony Schountz et al.   Viruses-Basel

An Innate Immunity-Regulating Virulence Determinant Is Uniquely Encoded within the Andes Virus Nucleocapsid Protein

(2014) V. Cimica et al.   mBio

Antiviral Efficacy of Favipiravir against Two Prominent Etiological Agents of Hantavirus Pulmonary Syndrome

(2013) David Safronetz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The adaptive immune response does not influence hantavirus disease or persistence in the Syrian hamster

(2013) Joseph Prescott et al.   IMMUNOLOGY

Induction of Hantaan virus-specific immune responses in C57BL/6 mice by immunization with a modified recombinant adenovirus containing the chimeric gene, GcS0.7

(2013) KAI LI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

A Recently Isolated Lassa Virus From Mali Demonstrates Atypical Clinical Disease Manifestations and Decreased Virulence in Cynomolgus Macaques

(2013) David Safronetz et al.   JOURNAL OF INFECTIOUS DISEASES

A Lethal Disease Model for Hantavirus Pulmonary Syndrome in Immunosuppressed Syrian Hamsters Infected with Sin Nombre Virus

(2013) R. L. Brocato et al.   JOURNAL OF VIROLOGY

Hamster-Adapted Sin Nombre Virus Causes Disseminated Infection and Efficiently Replicates in Pulmonary Endothelial Cells without Signs of Disease

(2013) D. Safronetz et al.   JOURNAL OF VIROLOGY

Mice Lacking Functional STAT1 Are Highly Susceptible to Lethal Infection with Lassa Virus

(2013) N. E. Yun et al.   JOURNAL OF VIROLOGY

Rescue of a Recombinant Machupo Virus from Cloned cDNAs and In Vivo Characterization in Interferon (  / ) Receptor Double Knockout Mice

(2013) M. Patterson et al.   JOURNAL OF VIROLOGY

Experimental Andes Virus Infection in Deer Mice: Characteristics of Infection and Clearance in a Heterologous Rodent Host

(2013) Jessica R. Spengler et al.   PLoS One

Infection of Type I Interferon Receptor-Deficient Mice with Various Old World Arenaviruses: A Model for Studying Virulence and Host Species Barriers

(2013) Toni Rieger et al.   PLoS One

A recombinant pseudotyped lentivirus expressing the envelope glycoprotein of Hantaan virus induced protective immunity in mice

(2013) Lan Yu et al.   Virology Journal

Ribavirin Protects Syrian Hamsters against Lethal Hantavirus Pulmonary Syndrome — After Intranasal Exposure to Andes Virus

(2013) Monica Ogg et al.   Viruses-Basel

Geographic Distribution and Genetic Characterization of Lassa Virus in Sub-Saharan Mali

(2013) David Safronetz et al.   PLoS Neglected Tropical Diseases

Transcriptional Profiling of the Circulating Immune Response to Lassa Virus in an Aerosol Model of Exposure

(2013) Shikha Malhotra et al.   PLoS Neglected Tropical Diseases

Favipiravir (T-705) Inhibits Junín Virus Infection and Reduces Mortality in a Guinea Pig Model of Argentine Hemorrhagic Fever

(2013) Brian B. Gowen et al.   PLoS Neglected Tropical Diseases

Phylogeny and Origins of Hantaviruses Harbored by Bats, Insectivores, and Rodents

(2013) Wen-Ping Guo et al.   PLoS Pathogens

Hantavirus-infection Confers Resistance to Cytotoxic Lymphocyte-Mediated Apoptosis

(2013) Shawon Gupta et al.   PLoS Pathogens

Pathogenesis of the Viral Hemorrhagic Fevers

(2012) Slobodan Paessler et al.   Annual Review of Pathology-Mechanisms of Disease

Construction and Nonclinical Testing of a Puumala Virus Synthetic M Gene-Based DNA Vaccine

(2012) R. L. Brocato et al.   Clinical and Vaccine Immunology

Rodent-borne hemorrhagic fevers: under-recognized, widely spread and preventable – epidemiology, diagnostics and treatment

(2012) Marco Goeijenbier et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Kinetics of Immune Responses in Deer Mice Experimentally Infected with Sin Nombre Virus

(2012) Tony Schountz et al.   JOURNAL OF VIROLOGY

Tacaribe Virus Causes Fatal Infection of An Ostensible Reservoir Host, the Jamaican Fruit Bat

(2012) A. Cogswell-Hawkinson et al.   JOURNAL OF VIROLOGY

Functional Interferon System Is Required for Clearance of Lassa Virus

(2012) N. E. Yun et al.   JOURNAL OF VIROLOGY

Reverse Genetics Recovery of Lujo Virus and Role of Virus RNA Secondary Structures in Efficient Virus Growth

(2012) E. Bergeron et al.   JOURNAL OF VIROLOGY

DNA Vaccine-Generated Duck Polyclonal Antibodies as a Postexposure Prophylactic to Prevent Hantavirus Pulmonary Syndrome (HPS)

(2012) Rebecca Brocato et al.   PLoS One

Effect of Ribavirin on Junin Virus Infection in Guinea Pigs

(2012) M. Salazar et al.   Zoonoses and Public Health

Pathogenesis of Lassa Fever

(2012) Nadezhda E. Yun et al.   Viruses-Basel

An animal model that reflects human disease: the common marmoset (Callithrix jacchus)

(2012) Ricardo Carrion et al.   Current Opinion in Virology

Immunogenicity of a multi-epitope DNA vaccine against hantavirus

(2012) Chen Zhao et al.   Human Vaccines & Immunotherapeutics

Severe Hemorrhagic Fever in Strain 13/N Guinea Pigs Infected with Lujo Virus

(2012) Brian H. Bird et al.   PLoS Neglected Tropical Diseases

Genetic Diversity of Thottapalayam Virus, a Hantavirus Harbored by the Asian House Shrew (Suncus murinus) in Nepal

(2011) Hae Ji Kang et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

A unifying hypothesis and a single name for a complex globally emerging infection: hantavirus disease

(2011) J. Clement et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

VP24 Is a Molecular Determinant of Ebola Virus Virulence in Guinea Pigs

(2011) Mathieu Mateo et al.   JOURNAL OF INFECTIOUS DISEASES

Modification of the adenoviral transfer vector enhances expression of the Hantavirus fusion protein GnS0.7 and induces a strong immune response in C57BL/6 mice

(2011) Pu-Yuan Li et al.   JOURNAL OF VIROLOGICAL METHODS

The Major Determinant of Attenuation in Mice of the Candid1 Vaccine for Argentine Hemorrhagic Fever Is Located in the G2 Glycoprotein Transmembrane Domain

(2011) C. G. Albarino et al.   JOURNAL OF VIROLOGY

Vesicular Stomatitis Virus-Based Vaccine Protects Hamsters against Lethal Challenge with Andes Virus

(2011) K. S. Brown et al.   JOURNAL OF VIROLOGY

T Cells Are Not Required for Pathogenesis in the Syrian Hamster Model of Hantavirus Pulmonary Syndrome

(2011) C. D. Hammerbeck et al.   JOURNAL OF VIROLOGY

In Vitro and In Vivo Activity of Ribavirin against Andes Virus Infection

(2011) David Safronetz et al.   PLoS One

Fusion with extracellular domain of cytotoxic T-lymphocyte-associated-antigen 4 leads to enhancement of immunogenicity of Hantaan virus DNA vaccines in C57BL/6 mice

(2011) Feng Liu et al.   Virology Journal

Pathogenesis of lassa fever in cynomolgus macaques

(2011) Lisa E Hensley et al.   Virology Journal

A STAT-1 knockout mouse model for Machupo virus pathogenesis

(2011) Steven B Bradfute et al.   Virology Journal

Puumala virus infection in Syrian hamsters (Mesocricetus auratus) resembling hantavirus infection in natural rodent hosts

(2011) Takahiro Sanada et al.   VIRUS RESEARCH

Pathogenesis and Host Response in Syrian Hamsters following Intranasal Infection with Andes Virus

(2011) David Safronetz et al.   PLoS Pathogens

A Global Perspective on Hantavirus Ecology, Epidemiology, and Disease

(2010) C. B. Jonsson et al.   CLINICAL MICROBIOLOGY REVIEWS

Pathogenesis of arenavirus hemorrhagic fevers

(2010) Marie-Laurence Moraz et al.   Expert Review of Anti-Infective Therapy

Rescue from Cloned cDNAs and In Vivo Characterization of Recombinant Pathogenic Romero and Live-Attenuated Candid #1 Strains of Junin Virus, the Causative Agent of Argentine Hemorrhagic Fever Disease

(2010) S. F. Emonet et al.   JOURNAL OF VIROLOGY

Mice Lacking Alpha/Beta and Gamma Interferon Receptors Are Susceptible to Junin Virus Infection

(2010) O. A. Kolokoltsova et al.   JOURNAL OF VIROLOGY

Hantavirus-like particles generated in CHO cells induce specific immune responses in C57BL/6 mice

(2010) Chuan Li et al.   VACCINE

TC83 replicon vectored vaccine provides protection against Junin virus in guinea pigs

(2010) Alexey V. Seregin et al.   VACCINE

Establishing Efficacy of Human Products Using Animals

(2010) P. J. Snoy   VETERINARY PATHOLOGY

T Cell-Dependence of Lassa Fever Pathogenesis

(2010) Lukas Flatz et al.   PLoS Pathogens

Molecular Determinants of Pichinde Virus Infection of Guinea Pigs-a Small Animal Model System for Arenaviral Hemorrhagic Fevers

(2009) Yuying Liang et al.   Annals of the New York Academy of Sciences

Rodent-borne diseases and their risks for public health

(2009) Bastiaan G Meerburg et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Early and Strong Immune Responses Are Associated with Control of Viral Replication and Recovery in Lassa Virus-Infected Cynomolgus Monkeys

(2009) S. Baize et al.   JOURNAL OF VIROLOGY

Adenovirus Vectors Expressing Hantavirus Proteins Protect Hamsters against Lethal Challenge with Andes Virus

(2009) D. Safronetz et al.   JOURNAL OF VIROLOGY

Evolutionary Insights from a Genetically Divergent Hantavirus Harbored by the European Common Mole (Talpa europaea)

(2009) Hae Ji Kang et al.   PLoS One

Vaccines for hantaviruses

(2009) Connie Schmaljohn   VACCINE

Host-Species Transferrin Receptor 1 Orthologs Are Cellular Receptors for Nonpathogenic New World Clade B Arenaviruses

(2009) Jonathan Abraham et al.   PLoS Pathogens

Seoul virus enhances regulatory and reduces proinflammatory responses in male Norway rats

(2008) Judith D. Easterbrook et al.   JOURNAL OF MEDICAL VIROLOGY

Secretory Expression and Purification of Recombinant Escherichia coli Heat-Labile Enterotoxin B Subunit and its Applications on Intranasal Vaccination of Hantavirus

(2008) Shouchun Cao et al.   MOLECULAR BIOTECHNOLOGY

Pathology of Puumala Hantavirus Infection in Macaques

(2008) Tarja Sironen et al.   PLoS One

Heat shock protein 70 fused to or complexed with Hantavirus nucleocapsid protein significantly enhances specific humoral and cellular immune responses in C57BL/6 mice

(2008) Jing Li et al.   VACCINE

Safety, immunogenicity, and efficacy of the ML29 reassortant vaccine for Lassa fever in small non-human primates

(2008) Igor S. Lukashevich et al.   VACCINE

Mixing of M segment DNA vaccines to Hantaan virus and Puumala virus reduces their immunogenicity in hamsters

(2008) Kristin W. Spik et al.   VACCINE

Truncated Recombinant Puumala Virus Nucleocapsid Proteins Protect Mice Against Challenge in Vivo

(2008) Piet Maes et al.   VIRAL IMMUNOLOGY

Chapare Virus, a Newly Discovered Arenavirus Isolated from a Fatal Hemorrhagic Fever Case in Bolivia

(2008) Simon Delgado et al.   PLoS Pathogens

Treatment of hantavirus pulmonary syndrome

(2007) Colleen B. Jonsson et al.   ANTIVIRAL RESEARCH

Treatment of Argentine hemorrhagic fever

(2007) Delia A. Enria et al.   ANTIVIRAL RESEARCH

Sex differences in the recognition of and innate antiviral responses to Seoul virus in Norway rats

(2007) Michele F. Hannah et al.   BRAIN BEHAVIOR AND IMMUNITY