Nobiletin suppresses the proliferation and induces apoptosis involving MAPKs and caspase-8/-9/-3 signals in human acute myeloid leukemia cells

Nobiletin Induces Inhibitions of Ras Activity and Mitogen-Activated Protein Kinase Kinase/Extracellular Signal-Regulated Kinase Signaling to Suppress Cell Proliferation in C6 Rat Glioma Cells

(2013) Koichi Aoki et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Hispolon Induces Apoptosis through JNK1/2-Mediated Activation of a Caspase-8, -9, and -3-Dependent Pathway in Acute Myeloid Leukemia (AML) Cells and Inhibits AML Xenograft Tumor Growth in Vivo

(2013) Pei-Ching Hsiao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Nobiletin attenuates metastasis via both ERK and PI3K/Akt pathways in HGF-treated liver cancer HepG2 cells

(2013) Ming-Der Shi et al.   PHYTOMEDICINE

Inhibitory Effects of Nobiletin on Hepatocellular CarcinomaIn VitroandIn Vivo

(2013) Xiuying Ma et al.   PHYTOTHERAPY RESEARCH

Synergistic Anti-inflammatory Effects of Nobiletin and Sulforaphane in Lipopolysaccharide-Stimulated RAW 264.7 Cells

(2012) Shanshan Guo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Matrine Induces Apoptosis in Human Acute Myeloid Leukemia Cells via the Mitochondrial Pathway and Akt Inactivation

(2012) Shenghui Zhang et al.   PLoS One

Nobiletin metabolites: Synthesis and inhibitory activity against matrix metalloproteinase-9 production

(2011) Tetsuta Oshitari et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Nobiletin, a Polymethoxy Flavonoid, Suppresses Bone Resorption by Inhibiting NFκB-Dependent Prostaglandin E Synthesis in Osteoblasts and Prevents Bone Loss Due to Estrogen Deficiency

(2011) Suguru Harada et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

MRx102, a triptolide derivative, has potent antileukemic activity in vitro and in a murine model of AML

(2011) B Z Carter et al.   LEUKEMIA

Anti-neuroinflammatory Activity of Nobiletin on Suppression of Microglial Activation

(2010) Yanji Cui et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Apoptotic effect of citrus fruit extract nobiletin on lung cancer cell line A549 in vitro and in vivo

(2010) Gang Luo et al.   CANCER BIOLOGY & THERAPY

H3K9 Histone Methyltransferase G9a Promotes Lung Cancer Invasion and Metastasis by Silencing the Cell Adhesion Molecule Ep-CAM

(2010) M.-W. Chen et al.   CANCER RESEARCH

Nobiletin, a citrus flavonoid, suppresses invasion and migration involving FAK/PI3K/Akt and small GTPase signals in human gastric adenocarcinoma AGS cells

(2010) Yi-Chieh Lee et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Cancer Prevention With Natural Compounds

(2010) Norleena P. Gullett et al.   SEMINARS IN ONCOLOGY

Irciniastatin A induces JNK activation that is involved in caspase-8-dependent apoptosis via the mitochondrial pathway

(2010) Takumi Chinen et al.   TOXICOLOGY LETTERS

Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: therapeutic implications for prostate cancer

(2009) Seong Soo Joo et al.   JOURNAL OF PINEAL RESEARCH

Anti-inflammatory and antitumor promotional effects of a novel urinary metabolite, 3',4'-didemethylnobiletin, derived from nobiletin

(2008) C.-S. Lai et al.   CARCINOGENESIS

Suppressive effects of nobiletin on hyperleptinemia and colitis-related colon carcinogenesis in male ICR mice

(2008) Shingo Miyamoto et al.   CARCINOGENESIS

Nobiletin, a Citrus Flavonoid, Improves Memory Impairment and A  Pathology in a Transgenic Mouse Model of Alzheimer's Disease

(2008) H. Onozuka et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Monodemethylated polymethoxyflavones from sweet orange (Citrus sinensis) peel Inhibit growth of human lung cancer cells by apoptosis

(2008) Hang Xiao et al.   MOLECULAR NUTRITION & FOOD RESEARCH