Platycodin D, a triterpenoid saponin from Platycodon grandiflorum, induces G2/M arrest and apoptosis in human hepatoma HepG2 cells by modulating the PI3K/Akt pathway

Platycodin D induces anoikis and caspase-mediated apoptosis via p38 MAPK in AGS human gastric cancer cells

(2012) Jaemoo Chun et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

WNT/β-catenin pathway mediates the anti-adipogenic effect of platycodin D, a natural compound found in Platycodon grandiflorum

(2011) Haeyong Lee et al.   LIFE SCIENCES

Platycodin D Induces Apoptosis in MCF-7 Human Breast Cancer Cells

(2010) Ji Sun Yu et al.   JOURNAL OF MEDICINAL FOOD

Update: Immunological Strategies for Prostate Cancer

(2010) Charles G. Drake et al.   Current Urology Reports

Platycodin D and 2″-o-acetyl-polygalacin D2 isolated from Platycodon grandiflorum protect ischemia/reperfusion injury in the gerbil hippocampus

(2009) Jung Hoon Choi et al.   BRAIN RESEARCH

Centrosome-associated regulators of the G2/M checkpoint as targets for cancer therapy

(2009) Yingmei Wang et al.   Molecular Cancer

Platycodin D induces apoptosis and decreases telomerase activity in human leukemia cells

(2008) Mun-Ock Kim et al.   CANCER LETTERS

Protective effect of saponins derived from the roots of Platycodon grandiflorum against carbon tetrachloride induced hepatotoxicity in mice

(2008) Kyung Jin Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

Saponins isolated from the root of Platycodon grandiflorum protect against acute ethanol-induced hepatotoxicity in mice

(2008) Tilak Khanal et al.   FOOD AND CHEMICAL TOXICOLOGY

Platycodin D induces mitotic arrestin vitro, leading to endoreduplication, inhibition of proliferation and apoptosis in leukemia cells

(2008) Mun-Ock Kim et al.   INTERNATIONAL JOURNAL OF CANCER

Platycodin D is a potent adjuvant of specific cellular and humoral immune responses against recombinant hepatitis B antigen

(2008) Yong Xie et al.   VACCINE