PET imaging with radiolabeled antibodies and tyrosine kinase inhibitors: immuno-PET and TKI-PET

Implementation of 89Zr production and in vivo imaging of B-cells in mice with 89Zr-labeled anti-B-cell antibodies by small animal PET/CT

(2011) Martin Walther et al.   APPLIED RADIATION AND ISOTOPES

[11C]Sorafenib: Radiosynthesis and preliminary PET study of brain uptake in P-gp/Bcrp knockout mice

(2011) Chiharu Asakawa et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A first synthesis of 18F-radiolabeled lapatinib: a potential tracer for positron emission tomographic imaging of ErbB1/ErbB2 tyrosine kinase activity

(2011) Falguni Basuli et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

In Vivo Imaging of Bcr-Abl Overexpressing Tumors with a Radiolabeled Imatinib Analog as an Imaging Surrogate for Imatinib

(2011) A. P. Glekas et al.   JOURNAL OF NUCLEAR MEDICINE

Radiolabelled proteins for positron emission tomography: Pros and cons of labelling methods

(2010) Vladimir Tolmachev et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Positive Progress in ImmunoPET—Not Just a Coincidence

(2010) Katelyn E. McCabe et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Immuno-Positron Emission Tomography: Shedding Light on Clinical Antibody Therapy

(2010) Guus A.M.S. van Dongen et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Biodistribution of 89Zr-trastuzumab and PET Imaging of HER2-Positive Lesions in Patients With Metastatic Breast Cancer

(2010) E C Dijkers et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Neratinib, an Irreversible Pan-ErbB Receptor Tyrosine Kinase Inhibitor: Results of a Phase II Trial in Patients With Advanced Non–Small-Cell Lung Cancer

(2010) Lecia V. Sequist et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase I Trial of the Irreversible EGFR and HER2 Kinase Inhibitor BIBW 2992 in Patients With Advanced Solid Tumors

(2010) Timothy A. Yap et al.   JOURNAL OF CLINICAL ONCOLOGY

89Zr-DFO-J591 for ImmunoPET of Prostate-Specific Membrane Antigen Expression In Vivo

(2010) J. P. Holland et al.   JOURNAL OF NUCLEAR MEDICINE

ImmunoSPECT and ImmunoPET of IGF-1R Expression with the Radiolabeled Antibody R1507 in a Triple-Negative Breast Cancer Model

(2010) S. Heskamp et al.   JOURNAL OF NUCLEAR MEDICINE

89Zr-Bevacizumab PET of Early Antiangiogenic Tumor Response to Treatment with HSP90 Inhibitor NVP-AUY922

(2010) W. B. Nagengast et al.   JOURNAL OF NUCLEAR MEDICINE

PET of Hypoxia with 89Zr-Labeled cG250-F(ab')2 in Head and Neck Tumors

(2010) B. A. W. Hoeben et al.   JOURNAL OF NUCLEAR MEDICINE

Folic Acid Conjugates for Nuclear Imaging of Folate Receptor-Positive Cancer

(2010) C. Muller et al.   JOURNAL OF NUCLEAR MEDICINE

Radiolabelled receptor-tyrosine-kinase targeting drugs for patient stratification and monitoring of therapy response: prospects and pitfalls

(2010) Vladimir Tolmachev et al.   LANCET ONCOLOGY

Biopharmaceutical benchmarks 2010

(2010) Gary Walsh   NATURE BIOTECHNOLOGY

Conjugation and radiolabeling of monoclonal antibodies with zirconium-89 for PET imaging using the bifunctional chelate p-isothiocyanatobenzyl-desferrioxamine

(2010) Maria J W D Vosjan et al.   Nature Protocols

Site-specifically 89Zr-labeled monoclonal antibodies for ImmunoPET

(2010) Jeff N. Tinianow et al.   NUCLEAR MEDICINE AND BIOLOGY

Measuring the Pharmacodynamic Effects of a Novel Hsp90 Inhibitor on HER2/neu Expression in Mice Using 89Zr-DFO-Trastuzumab

(2010) Jason P. Holland et al.   PLoS One

Antibody Vectors for Imaging

(2010) Tove Olafsen et al.   SEMINARS IN NUCLEAR MEDICINE

Radioimmunoimaging with Longer-Lived Positron-Emitting Radionuclides: Potentials and Challenges

(2009) Tapan K. Nayak et al.   BIOCONJUGATE CHEMISTRY

Positron Emission Tomography (PET) Imaging with [11C]-Labeled Erlotinib: A Micro-PET Study on Mice with Lung Tumor Xenografts

(2009) A. A. Memon et al.   CANCER RESEARCH

124I-L19-SIP for immuno-PET imaging of tumour vasculature and guidance of 131I-L19-SIP radioimmunotherapy

(2009) Bernard M. Tijink et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

p-Isothiocyanatobenzyl-desferrioxamine: a new bifunctional chelate for facile radiolabeling of monoclonal antibodies with zirconium-89 for immuno-PET imaging

(2009) Lars R. Perk et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Radiation Dosimetry of 89Zr-Labeled Chimeric Monoclonal Antibody U36 as Used for Immuno-PET in Head and Neck Cancer Patients

(2009) P. K.E. Borjesson et al.   JOURNAL OF NUCLEAR MEDICINE

Development and Characterization of Clinical-Grade 89Zr-Trastuzumab for HER2/neu ImmunoPET Imaging

(2009) E. C.F. Dijkers et al.   JOURNAL OF NUCLEAR MEDICINE

[11C]Gefitinib ([11C]Iressa): Radiosynthesis, In Vitro Uptake, and In Vivo Imaging of Intact Murine Fibrosarcoma

(2009) Ming-Rong Zhang et al.   MOLECULAR IMAGING AND BIOLOGY

Standardized methods for the production of high specific-activity zirconium-89

(2009) Jason P. Holland et al.   NUCLEAR MEDICINE AND BIOLOGY

Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody-Cytotoxic Drug Conjugate

(2008) G. D. Lewis Phillips et al.   CANCER RESEARCH

Quantitative PET imaging of Met-expressing human cancer xenografts with 89Zr-labelled monoclonal antibody DN30

(2008) Lars R. Perk et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Evaluation of [18F]gefitinib as a molecular imaging probe for the assessment of the epidermal growth factor receptor status in malignant tumors

(2008) Helen Su et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Disparity Between In Vivo EGFR Expression and 89Zr-Labeled Cetuximab Uptake Assessed with PET

(2008) H. J.W.L. Aerts et al.   JOURNAL OF NUCLEAR MEDICINE