Article
Infectious Diseases
Audrey Lenhart, Carmen Elena Castillo, Elci Villegas, Neal Alexander, Veerle Vanlerberghe, Patrick van der Stuyft, Philip S. McCall
Summary: A large-scale trial in Venezuela found that the use of insecticide treated curtains and water jar covers can effectively control dengue vector populations, especially when used in combination.
PLOS NEGLECTED TROPICAL DISEASES
(2022)
Article
Entomology
Fiza Arshad, Arvind Sharma, Charleen Lu, Monika Gulia-Nuss
Summary: RNA-interference (RNAi) is a standard technique for functional genomics in adult mosquitoes, but its application in immature stages has been challenging. This study successfully developed a simple method for RNAi in mosquito pupae by soaking them in water containing dsRNA, without the need for carrier molecules or microinjections. The technique can be used to study gene expression in pupae and potentially identify new targets for mosquito control at early life stages.
Article
Multidisciplinary Sciences
Shinji Kasai, Kentaro Itokawa, Nozomi Uemura, Aki Takaoka, Shogo Furutani, Yoshihide Maekawa, Daisuke Kobayashi, Nozomi Imanishi-Kobayashi, Michael Amoa-Bosompem, Katsunori Murota, Yukiko Higa, Hitoshi Kawada, Noboru Minakawa, Tran Chi Cuong, Nguyen Thi Yen, Tran Vu Phong, Sath Keo, Kroesna Kang, Kozue Miura, Lee Ching Ng, Hwa-Jen Teng, Samuel Dadzie, Sri Subekti, Kris Cahyo Mulyatno, Kyoko Sawabe, Takashi Tomita, Osamu Komagata
Summary: Aedes aegypti, the main mosquito vector for dengue and other arboviral infectious diseases, has developed high levels of pyrethroid resistance in populations collected from Vietnam and Cambodia. This resistance could pose a serious threat to the control of dengue fever and other Aedes-borne infectious diseases.
Article
Multidisciplinary Sciences
Talya Shragai, Juliana Perez-Perez, Marcela del Pilar Quimbayo-Forero, Raul Rojo, Laura C. Harrington, Guillermo Rua-Uribe
Summary: Dengue is becoming an increasing global threat in rapidly growing urban areas. This study analyzes nine years of dengue case data in Medellin, Colombia and finds that changes in accessibility and usage of public transit are correlated with changes in the spread and magnitude of localized outbreaks. Locations closer to and with greater utilization of public transit have higher dengue incidence, with a stronger effect observed in lower socioeconomic status areas. These results emphasize the importance of public health services in conjunction with urban growth.
SCIENTIFIC REPORTS
(2022)
Article
Environmental Sciences
Cory W. Morin, Samuel Sellers, Kristie L. Ebi
Summary: This study explored the relationship between seasonal climate variability and dengue fever (DF) in Brazil using temperature-based models. The results showed that areas with higher mosquito survival probabilities and shorter extrinsic incubation periods (EIPs) were more likely to have DF case reports, but with significant intra-annual variability. The study also extrapolated the findings to the Americas, mapping the seasonal change in the range of areas suitable for dengue virus transmission and the population living in those areas using climate data from the past decade (2010-2019).
ENVIRONMENTAL RESEARCH LETTERS
(2022)
Article
Public, Environmental & Occupational Health
Kyle R. Ryff, Aidsa Rivera, Dania M. Rodriguez, Gilberto A. Santiago, Freddy A. Medina, Esther M. Ellis, Jomil Torres, Ann Pobutsky, Jorge Munoz-Jordan, Gabriela Paz-Bailey, Laura E. Adams
Summary: From 2010 to 2020, approximately 30,000 cases of dengue were reported in the US territories, with the highest incidence during outbreak years. Children and adolescents aged <20 years were disproportionately affected, highlighting the need for interventions tailored for this population. Ongoing education for healthcare providers and dengue case surveillance and serotyping are important for improving patient outcomes and guiding future control measures.
MMWR SURVEILLANCE SUMMARIES
(2023)
Review
Immunology
Zhuanzhuan Liu, Qingxin Zhang, Liya Li, Junjie He, Jinyang Guo, Zichen Wang, Yige Huang, Zimeng Xi, Fei Yuan, Yiji Li, Tingting Li
Summary: This review explores the correlations between temperature and dengue epidemics, including the distribution and development of Aedes mosquitoes, the structure of DENV, and the vector competence of Aedes mosquitoes. Additionally, it discusses the immune and metabolic mechanism through which temperature affects the vector competence of Aedes mosquitoes to transmit DENV.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Multidisciplinary Sciences
L. L. Lima, A. P. F. Atman
Summary: In an increasingly interconnected society, preventing epidemics has become a major challenge. Using an agent-based model, the authors investigated the network morphology of a dengue endemic region considering different serotypes and a small population. The simulation results indicate that the spread of dengue is primarily driven by human-to-human and human-to-mosquito interaction, reinforcing the importance of controlling the vector to prevent episodes of epidemic outbreaks.
Article
Entomology
Maria E. Santana-Roman, Paola Maycotte, Salvador Uribe-Carvajal, Cristina Uribe-Alvarez, Nayeli Alvarado-Medina, Mohsin Khan, Aleem Siddiqui, Victoria Pando-Robles
Summary: Dengue is a growing public health concern without specific treatment, and vector control remains crucial for prevention. Studies show that DENV infection alters mitochondrial physiology in mosquito cells, affecting redox metabolism and membrane potential. The maintenance of mitochondrial function through fusion may play a vital role in the DENV-infected cells.
Article
Medicine, General & Internal
Triwibowo Ambar Garjito, Lulus Susanti, Mujiyono Mujiyono, Mega Tyas Prihatin, Dwi Susilo, Sidiq Setyo Nugroho, Mujiyanto Mujiyanto, Raden Ajeng Wigati, Tri Baskoro Tunggul Satoto, Sylvie Manguin, Laurent Gavotte, Roger Frutos
Summary: There are various methods to collect and assess the abundance of dengue vector mosquitoes, but the lack of long-term sampling methods may result in variability and lack of statistical significance in the results. There is no correlation between the collection methods and the presence of dengue virus in mosquitoes or the incidence of dengue, and the efficacy of a given method is inconsistent across different locations.
FRONTIERS IN MEDICINE
(2021)
Article
Immunology
Jessica E. Manning, Sophana Chea, Daniel M. Parker, Jennifer A. Bohl, Sreyngim Lay, Allyson Mateja, Somnang Man, Sreynik Nhek, Aiyana Ponce, Sokunthea Sreng, Dara Kong, Soun Kimsan, Claudio Meneses, Michael P. Fay, Seila Suon, Rekol Huy, Chanthap Lon, Rithea Leang, Fabiano Oliveira
Summary: Results from a longitudinal pediatric cohort in Cambodia indicate that children with high levels of antibodies to Aedes aegypti mosquito saliva are more likely to contract dengue fever, but are less likely to show clinical symptoms.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Chemistry, Medicinal
Chao Yang, Wansheng Xie, Heqian Zhang, Wenjian Xie, Tiantian Tian, Zhiwei Qin
Summary: Dengue is an acute tropical infectious disease transmitted by mosquitoes, posing a major challenge to global public health. The lack of clinically proven specific drugs for prevention and treatment is mainly due to the incomplete understanding of the pathogenesis of dengue fever.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2022)
Article
Environmental Sciences
Maria S. Lopez, Andre A. Gomez, Gabriela V. Müller, Elisabet Walker, Michael A. Robert, Elizabet L. Estallo
Summary: This study analyzed the relationship between climate change and dengue fever, and found that there is a correlation between increasing temperatures and the rise in dengue cases as well as its geographical expansion. This suggests that climate change is an important driver of the continuous spread of dengue fever in Argentina.
ENVIRONMENTAL HEALTH PERSPECTIVES
(2023)
Article
Parasitology
Maria C. Carrasquilla, Mario I. Ortiz, Cielo Leon, Silvia Rondon, Manisha A. Kulkarni, Benoit Talbot, Beate Sander, Heriberto Vasquez, Juan M. Cordovez, Camila Gonzalez
Summary: A study conducted in Ibague, Colombia found that Aedes aegypti and Aedes albopictus mosquitoes are vectors for dengue, Zika, and chikungunya viruses, with dengue and chikungunya circulating in the area but Zika virus remaining undetected. The research results showed that mosquitoes were mainly found in low socioeconomic areas and indoors, with a higher number of female mosquitoes that have fed on human blood, indicating a high risk of arbovirus transmission in Ibague.
PARASITES & VECTORS
(2021)
Article
Parasitology
Shih-Che Weng, Po-Nien Tsao, Shin-Hong Shiao
Summary: This study found that blood glucose enhances DENV replication in mosquitoes, leading to increased virus transmission. The activation of AKT and TOR signaling pathways plays a crucial role in facilitating this process. This insight may contribute to understanding the relationship between dengue fever and diabetes mellitus and could potentially offer new targets for antiviral therapies.
PARASITES & VECTORS
(2021)