Editorial Material
Biology
Stephanie M. Holm, John Balmes
Summary: Pollution from landscape fires, increasing due to climate change, leads to lower birthweights in babies in low- and middle-income countries.
Article
Multidisciplinary Sciences
Ahmed Tahir Ahmed, Abdifatah Elmi Farah, Hussein Nooh Ali, Muse Obsiye Ibrahim
Summary: The early neonatal mortality rate in Ethiopia's Somali region is estimated to be 130 per 1000 live births, with 130 newborns unable to celebrate their seventh day in every 1000 live births. Hypothermia, prematurity, maternal death at birth, and shorter length of stay in the NICU increase the chance of neonatal mortality at an early stage, while neonatal resuscitation has a protective effect against neonatal mortality. Similarly, birth asphyxia, preterm birth, sepsis, and congenital abnormalities are major causes of admission and death in the NICU. The magnitude of early neonatal mortality is considerable, and most of the determinants are preventable.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Somashekhar Marutirao Nimbalkar, Viral Thakorbhai Patel, Dipen Vasudev Patel, Ajay Gajanan Phatak
Summary: The objective of this study was to determine if the use of the hypothermia-detecting bracelet, BEMPU, improves the duration of Kangaroo Mother Care (KMC) at home by one hour. The study conducted a parallel-group randomized controlled trial in a step-down nursery of a teaching hospital. The results showed that the BEMPU group had significantly higher daily time spent doing KMC in the first, second, third and fourth weeks compared to the control group. Therefore, BEMPU improved the daily duration of KMC hours at home over four weeks compared to the control group.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Wei-Tse Chiu, Yi-Hsuan Lu, Yin-Ting Chen, Yin Ling Tan, Yi-Chieh Lin, Yu-Lien Chen, Hung-Chieh Chou, Chien-Yi Chen, Ting-An Yen, Po-Nien Tsao
Summary: This study aimed to design a standard prevention bundle to decrease the rate of hypothermia among VLBW infants after birth and assess its short-term outcomes. By analyzing the primary causes of hypothermia, developing corresponding solutions, and implementing a prevention bundle, the incidence of neonatal hypothermia significantly decreased and the short-term outcomes of VLBW infants improved, particularly with a decreased incidence of intraventricular hemorrhage (IVH).
Article
Pediatrics
Vishnu-Priya Akula, Achyuth Sriram, Sherian Xu, Eileen Walsh, Krisa Van Meurs, Matthew Cranshaw, Michael Kuzniwiecz
Summary: Mild neonatal encephalopathy may lead to adverse short- and long-term outcomes, including developmental disorders and motor and speech delay. The group with mild encephalopathy had significantly higher rates of adverse outcomes compared to the unexposed group.
PEDIATRIC RESEARCH
(2023)
Article
Agriculture, Dairy & Animal Science
Bryony S. Tucker, Kiro R. Petrovski, Roy N. Kirkwood
Summary: The lighter a piglet is, the worse its ability to regulate body temperature after birth. A study found that providing piglets with a warm saline injection can improve their temperature recovery, colostrum intake, and survival rate.
Article
Infectious Diseases
A. J. Kuhle, C. B. Patsche, A. Floe, A. Sifna, V Gomes, C. Wejse, F. Rudolf
Summary: In an urban surveillance site with a high burden of tuberculosis in Guinea-Bissau, tuberculosis was found to be a common cause of death not only among patients diagnosed with tuberculosis, but also among those who were not diagnosed and the general population. This suggests a low detection rate of tuberculosis.
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
(2022)
Article
Agriculture, Dairy & Animal Science
Amelie Mugnier, Virginie Gaillard, Sylvie Chastant
Summary: The mortality rate in the first two months of life is high in canine species, but can be improved by early identification of high-risk neonates. Researchers analyzed data from 8550 puppies born in 127 French breeding kennels and found that low-birth-weight puppies grew slower in the first few days but had higher growth rates later. Thresholds for growth rates were established to identify puppies at higher risk of mortality and improve their chances of survival.
Article
Multidisciplinary Sciences
Alice Hoffsten, Laszlo Markasz, Katharina Ericson, Leif D. Nelin, Richard Sindelar
Summary: Autopsy determined the final cause of death in one-third of cases, and necrotizing enterocolitis as a cause of death increased significantly during the study period. The autopsy rate did not change significantly between the two study periods.
SCIENTIFIC REPORTS
(2021)
Article
Immunology
Frederik Schaltz-Buchholzer, Peter Aaby, Isaquel Silva, Ivan Monteiro, Tobias R. Kollmann, Nelly Amenyogbe, Morten Bjerregaard-Andersen, Christine Stabell Benn
Summary: This study suggests that maternal BCG vaccine may be associated with reduced overall NICU mortality rate in newborns.
JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Obstetrics & Gynecology
Diane Korb, Francois Goffinet, Loic Sentilhes, Gilles Kayem, Marie Victoire Senat, Elie Azria, Thomas Schmitz
Summary: This study assessed the survival of very preterm twins to discharge without severe neonatal morbidity based on the planned mode of delivery. The results showed that planned cesarean delivery was not associated with higher survival rates compared to planned vaginal delivery. This suggests that very preterm delivery should not automatically be an indication for planned cesarean in twin pregnancies.
OBSTETRICS AND GYNECOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Stine Byberg, Peter Aaby, Amabelia Rodrigues, Christine Stabell Benn, Ane Baerent Fisker
Summary: The study in Guinea-Bissau found that implementing the "MV-for-all-policy" increased measles vaccine coverage but did not have a significant impact on overall mortality. The effectiveness of the MV-for-all policy varied over time, with potential interactions with other childhood interventions influencing the results.
Article
Pediatrics
Hilary K. Brown, Simon Chen, Astrid Guttmann, Susan M. Havercamp, Susan L. Parish, Joel G. Ray, Simone N. Vigod, Lesley A. Tarasoff, Yona Lunsky
Summary: The study found that newborns of women with disabilities have an elevated risk of complications, especially for women with intellectual or developmental disabilities and those with multiple disabilities. This indicates that women with disabilities may require special attention and care before and during pregnancy.
Article
Medicine, General & Internal
Nansi S. Boghossian, Marco Geraci, Ciaran S. Phibbs, Scott A. Lorch, Erika M. Edwards, Jeffrey D. Horbar
Summary: This study examined the distribution of extremely preterm births between 2009 and 2020 based on neonatal intensive care resources at the delivery hospital. The findings revealed concerning trends of deregionalization in the level of care for infants born at 22 to 29 weeks' gestation.
Article
Environmental Sciences
Jiawen Liao, Yang Liu, Kyle Steenland, Ajay Pillarisetti, Lisa M. Thompson, Sagnik Dey, Kalpana Balakrishnan, Thomas Clasen
Summary: A study conducted in India shows an association between exposure to PM2.5 during the in utero and post-delivery periods and child survival. This study highlights the need for measures to reduce ambient air pollution levels, especially during pregnancy and early life stages, in India and other countries where guideline values are exceeded.
ENVIRONMENTAL HEALTH PERSPECTIVES
(2022)
Article
Immunology
Kristoffer Jarlov Jensen, Lola Kathe Tolstrup, Darryn L. Knobel, Peter Aaby, Gregers Jungersen, Lars Erik Larsen, Charlotte Sonne Kristensen, Christine Stabell Benn
Summary: This study investigated the non-specific effects (NSE) of non-live rabies vaccine in piglets and the potential modifying effect of maternal priming with the rabies vaccine. The results showed that the rabies vaccine may have a beneficial effect in female piglets, but a negative effect in (castrated) male piglets from rabies-naive sows. However, these effects had waned by 12 weeks of age.
Article
Immunology
Marcus Kjaer Sorensen, Frederik Schaltz-Buchholzer, Andreas Moller Jensen, Sebastian Nielsen, Ivan Monteiro, Peter Aaby, Christine Stabell Benn
Summary: This study conducted a trial on low weight infants in Guinea-Bissau and did not find an association between early diphtheria-tetanus-pertussis (DTP) vaccine administration and increased mortality in female infants. The differences in results compared to previous studies may be partly due to a decline in overall mortality and changes in vaccination practices.
Article
Immunology
Frederik Schaltz-Buchholzer, Marcus Kjaer Sorensen, Christine Stabell Benn, Peter Aaby
Summary: BCG vaccination may provide protection against childhood mortality, reducing both tuberculosis-related deaths and deaths from respiratory infections.
Article
Infectious Diseases
Peter Aaby, Heike Thoma, Klaus Dietz
Summary: This study examined measles mortality in an isolated German village, revealing that nearly all children under 14 years of age were affected by the epidemic. The overall case fatality ratio was 6.4%, with a higher rate of mortality observed among boys infected by girls in the household.
JOURNAL OF INFECTION
(2022)
Article
Infectious Diseases
Frederik Schaltz-Buchholzer, Christian Bjerregard Oland, Mike Berendsen, Morten Bjerregaard-Andersen, Elise Brenno Stjernholm, Christian N. Golding, Ivan Monteiro, Peter Aaby, Christine Stabell Benn
Summary: Maternal BCG vaccination is associated with a reduced risk of severe infection in newborns, especially for males. Providing BCG to adults without a vaccination scar might enhance their offspring's capacity to handle severe infections.
JOURNAL OF INFECTION
(2022)
Article
Immunology
Frederik Schaltz-Buchholzer, Peter Aaby, Isaquel Silva, Ivan Monteiro, Tobias R. Kollmann, Nelly Amenyogbe, Morten Bjerregaard-Andersen, Christine Stabell Benn
Summary: This study suggests that maternal BCG vaccine may be associated with reduced overall NICU mortality rate in newborns.
JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Health Care Sciences & Services
Anna Schneider-Kamp, Helle Lykke Nielsen, Morten Sodemann
Summary: This article explores the potential of a patientological perspective to enhance our understanding of and tailor care pathways. The study emphasizes the importance of cultural and social capital of patients and their relatives in designing effective tailored care pathways.
JOURNAL OF EVALUATION IN CLINICAL PRACTICE
(2023)
Article
Primary Health Care
Frode F. Jacobsen, Stinne Glasdam, Limke M. Schopman, Morten Sodemann, Maria E. T. C. van den Muijsenbergh, Gudmund agotnes
Summary: The aim of this study is to identify important factors for immigrants' health and well-being, their use of primary health care and other non-specialised services, and how primary health care can support healthy ageing of immigrants. Findings reveal that factors such as socio-economic position, inter-generational relationships, country-specific factors, and communication skills of health professionals are important for older immigrants' health and health-seeking behaviour.
PRIMARY HEALTH CARE RESEARCH AND DEVELOPMENT
(2023)
Article
Pharmacology & Pharmacy
Camilla Lynnerup, Charlotte Rossing, Morten Sodemann, Jesper Ryg, Anton Pottegard, Dorthe Nielsen
Summary: Little is known about the combined effect of risk factors in patients with language barriers or dementia. This study aimed to investigate medication safety among older migrants with cognitive disorders. Eight interviews were conducted with patients and relatives, and three main themes were identified: potential threats to medication safety, communication challenges and lack of medication information, and everyday life with medication.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
(2023)
Review
Infectious Diseases
Christine S. Benn, Peter Aaby
Summary: Measles vaccine may have beneficial effects beyond preventing measles infection, possibly due to measles-induced immune amnesia or beneficial non-specific immune training effects. Epidemiological studies support the hypothesis of immune amnesia, but there are also contradictory observations.
JOURNAL OF INFECTION
(2023)
Article
Immunology
Anne Marie Rosendahl Madsen, Frederik Schaltz-Buchholzer, Sebastian Nielsen, Thomas Benfield, Morten Bjerregaard-Andersen, Lars Skov Dalgaard, Christine Dam, Sisse Bolm Ditlev, Gulia Faizi, Mihnaz Azizi, Zainab Nadhim Hameed, Isik Somuncu Johansen, Poul-Erik Kofoed, Tyra Grove Krause, Gitte Schultz Kristensen, Ellen Christine Leth Loekkegaard, Christian Backer Mogensen, Libin Mohamed, Emilie Sundhaugen Oedegaard, Anne Ostenfeld, Marcus Kjaer Soerensen, Christian Wejse, Mihai G. Netea, Peter Aaby, Christine Stabell Benn
Summary: In a randomized clinical trial among Danish health care workers, BCG vaccination had no overall effect on absenteeism, COVID-19 incidence, hospitalization risk, or self-reported infectious diseases. BCG revaccination was associated with increased COVID-19 incidence, but reduced hospitalization risk.
JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Health Care Sciences & Services
Daria Schwalbe, Morten Sodemann, Maria Iachina, Bente Mertz Norgard, Nina Hoy Chodkiewicz, Jette Ammentorp
Summary: The study aims to gain a comprehensive understanding of the causes and patterns of nonattendance at Danish hospitals and identify effective interventions. It utilizes mixed methods, including quantitative data analysis and qualitative studies. The study highlights the need for a more holistic approach to address relational and organizational factors contributing to hospital no-shows.
JMIR RESEARCH PROTOCOLS
(2023)
Article
Medicine, General & Internal
Sanne Marie Thysen, Andreas Moller Jensen, Julie Odgaard Vedel, Igualdino da Silva Borges, Peter Aaby, Aksel Karl Georg Jensen, Christine Stabell Benn, Ane Baerent Fisker
Summary: The study aims to assess the impact of providing BCG vaccine at the first health-facility contact on early infant mortality and morbidity in a rural setting in Guinea-Bissau.
Meeting Abstract
Pharmacology & Pharmacy
Camilla Lynnerup, Charlotte Rossing, Morten Sodemann, Jesper Ryg, Anton Pottegard, Dorthe Nielsen
INTERNATIONAL JOURNAL OF CLINICAL PHARMACY
(2022)
Meeting Abstract
Pharmacology & Pharmacy
Camilla Lynnerup, Charlotte Rossing, Morten Sodemann, Jesper Ryg, Anton Pottegard, Dorthe Nielsen
INTERNATIONAL JOURNAL OF CLINICAL PHARMACY
(2022)