Journal
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
Volume 44, Issue 4, Pages 1186-1193Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/21691401.2015.1014093
Keywords
cell uptake; gene therapy; magnetic nanoparticles; non-viral platforms
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Funding
- Department of Medical Nanotechnology, Faculty of Advanced Medical Science of Tabriz University
- Drug Applied Research Center Tabriz University of Medical Sciences Grant
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Gene therapy is defined as the direct transfer of genetic material to tissues or cells for the treatment of inherited disorders and acquired diseases. For gene delivery, magnetic nanoparticles (MNPs) are typically combined with a delivery platform to encapsulate the gene, and promote cell uptake. Delivery technologies that have been used with MNPs contain polymeric, viral, as well as non-viral platforms. In this review, we focus on targeted gene delivery using MNPs.
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