Journal
TRENDS IN GENETICS
Volume 25, Issue 11, Pages 479-481Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tig.2009.09.009
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DMRT1, a mammalian gene related to sex-determining genes in flies and nematodes, is located in a region of the human genome that is important for sex development. This suggests that a common thread might run through the evolution of sex-determining mechanisms from worms to humans. New data show that DMRT1 can cause sex reversal in chickens, adding support to this hypothesis.
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