Journal
TRENDS IN GENETICS
Volume 24, Issue 2, Pages 59-63Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tig.2007.11.007
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Archeal proteomes can be clustered into two groups based on their cysteine content. One group of proteomes displays a low cysteine content (similar to 0.7% of the entire proteome), whereas the second group contains twice as many cysteines as the first (similar to 1.3%). All cysteine-rich organisms belong to the methanogenic Archaea, which generates special cysteine clusters associated with primitive metabolic reactions. Our findings suggest that cysteine plays an important role in early forms of life.
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