Article
Medicine, General & Internal
Murat Karatas, Erhan Tatar, Cenk Simsek, Ali Murat Yildirim, Adam Uslu
Summary: The study found that living kidney donors tend to develop obesity after donation, and there is an independent relationship between baseline serum uric acid level and obesity development. Kidney donors with high uric acid levels have a significantly higher risk of developing obesity.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2021)
Article
Pediatrics
Yi-Ting Yeh, Chinsu Liu, Hsin-Lin Tsai, Cheng-Yen Chen, Niang-Cheng Lin, Jei-Wen Chang, Pei-Chen Tsao, Yu-Sheng Lee, Cheng-Yuan Hsia, Che-Chuan Loong
Summary: This study evaluated the outcomes of patients under 6 months old undergoing living donor liver transplantation, finding that although challenging, the procedure yielded favorable outcomes dependent on underlying causes and technical innovations.
JOURNAL OF PEDIATRIC SURGERY
(2021)
Article
Urology & Nephrology
Takahisa Hiramitsu, Toshihide Tomosugi, Kenta Futamura, Manabu Okada, Yutaka Matsuoka, Norihiko Goto, Toshihiro Ichimori, Shunji Narumi, Asami Takeda, Takaaki Kobayashi, Kazuharu Uchida, Yoshihiko Watarai
Summary: This study investigated the impact of age differences between older adult living donors and recipients on kidney transplantation outcomes. The results showed that kidney transplants from older adult donors to older adult recipients had the highest risk of graft loss and mortality, with recipients having lower estimated glomerular filtration rates.
KIDNEY INTERNATIONAL REPORTS
(2021)
Article
Gastroenterology & Hepatology
Tomoharu Yoshizumi, Shinji Itoh, Mototsugu Shimokawa, Shoichi Inokuchi, Noboru Harada, Kazuki Takeishi, Yohei Mano, Shohei Yoshiya, Takeshi Kurihara, Yoshihiro Nagao, Toru Ikegami, Yuji Soejima, Masaki Mori
Summary: The study demonstrates that simultaneous splenectomy after living donor liver transplantation can prevent small-for-size graft syndrome and improve graft survival rates. It is recommended to perform simultaneous splenectomy for patients with predicted small grafts, portal hypertension, or high portal pressure.
JOURNAL OF HEPATOLOGY
(2021)
Article
Immunology
Fan Zhang, Saifu Yin, Yu Fan, Turun Song, Zhongli Huang, Jiayu Liang, Jiapei Wu, Youmin Yang, Tao Lin, Xianding Wang
Summary: This study found that the secretor status of both donors and recipients may have an impact on the outcomes of ABO incompatibility kidney transplantation. Recipients with weak secretor status may have better post-transplant renal function, while recipients from secretor donors had a lower incidence of graft rejection in the first year after transplantation.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Immunology
Ajay Kumar Baranwal, Sanjeev Goswami, Sanjay Kumar Agarwal, Gurvinder Kaur, Narinder Kumar Mehra
Summary: Not all anti-HLA donor-specific antibodies are harmful to renal allografts. The ability of antibodies to activate the C1q complement seems to be a crucial factor in determining whether DSAs are clinically inert or detrimental. Those DSAs that were able to fixate C1q were associated with a significantly higher risk of antibody-mediated rejection compared to those that did not show C1q fixation.
SCANDINAVIAN JOURNAL OF IMMUNOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Daisuke Nakajima, Satona Tanaka, Tadashi Ikeda, Shiro Baba, Hidefumi Hiramatsu, Takenori Suga, Akihiro Ohsumi, Hiroshi Date
Summary: This study evaluated the outcome of living-donor segmental lung transplantation in pediatric patients. The results showed that the procedure was technically difficult but feasible, with acceptable outcomes. The transplantation was successful in most cases, with only a few complications.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Medicine, General & Internal
Li-Min Hu, Hsin- Tsai, Chao-Wei Lee, Hui-Ming Chen, Wei-Chen Lee, Huang-Ping Yu
Summary: This study found that preoperative serum uric acid level is associated with early allograft dysfunction (EAD), with lower uric acid levels being linked to higher incidence and risk of EAD. This provides a new predictor for evaluating EAD and may have a protective effect against EAD development.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Surgery
Erzsi Tegzess, Antonio W. Gomes Neto, Robert A. Pol, Silke E. de Boer, Hessel Peters-Sengers, Jan-Stephan F. Sanders, Stefan P. Berger
Summary: In elderly kidney transplant recipients, living donor kidneys have significantly better nondeath-censored graft survival compared to regularly allocated and Eurotransplant Senior Program kidneys. However, there is decreased death-censored graft loss for living donor kidney recipients, while graft survival in regularly allocated and ESP kidneys remains satisfactory. Patient survival after 5 years does not show significant differences among the three types of donor kidneys.
TRANSPLANT INTERNATIONAL
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yerkezhan Kalshabay, Zhamilya Zholdybay, Michele Di Martino, Ulykbek Medeubekov, Dinara Baiguissova, Akmaral Ainakulova, Maksat Doskhanov, Bolatbek Baimakhanov
Summary: The aim of this retrospective study was to compare and evaluate the accuracy of three different approaches of liver volume quantification in living donor transplantations. The manual method showed the best correlation with graft weight. There was no significant difference in correlation coefficients between all three methods.
INSIGHTS INTO IMAGING
(2023)
Article
Pediatrics
Hagit Porn-Feldman, Miriam Davidovits, Elhanan Nahum, Avichai Weissbach, Eytan Kaplan, Gili Kadmon
Summary: In children undergoing renal transplantation, indices of fluid overload above 80 ml/kg are associated with improved renal function. Fluid overload may have short- and long-term benefits on renal function after pediatric renal transplantation.
PEDIATRIC RESEARCH
(2021)
Article
Nutrition & Dietetics
Kao-Ming Hsu, Pei-Ru Lin, Ping-Fang Chiu, Yao-Peng Hsieh
Summary: This study investigated the subsequent renal function change following incident infectious diseases in living-donor liver transplant recipients. The results showed that hospitalization with major infections or pneumonia increased the risk of eGFR decline and adverse renal outcomes in these patients.
Article
Multidisciplinary Sciences
Jungchan Park, Seung-Hwa Lee, Mi Sook Gwak, Justin Sangwook Ko, Sangbin Han, Gyu-Seong Choi, Jae Won Joh, Jongman Kim, Gaab Soo Kim
Summary: This study investigated the impact of NLR change on graft survival in living donor liver transplantation, finding that a decrease in NLR was associated with higher graft failure rates. Factors associated with NLR decrease included preoperative NLR, MELD score, intraoperative inotropic infusion and operative duration. Further research is needed to confirm these findings.
SCIENTIFIC REPORTS
(2021)
Review
Biochemistry & Molecular Biology
Alessandro Parente, Hwui-Dong Cho, Ki-Hun Kim, Andrea Schlegel
Summary: The aim of this study was to assess the association between graft-to-recipient weight ratio (GRWR) and hepatocellular carcinoma (HCC) recurrence in adult-to-adult living donor liver transplantation (LDLT). Three studies were identified, involving a total of 782 patients. The results showed that GRWR < 0.8% was associated with lower survival rates and higher tumor recurrence rates in HCC recipients, particularly for patients with HCC outside the established criteria. Considering individual GRWR as a contributor to HCC recurrence in LDLT patients may be beneficial.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Gastroenterology & Hepatology
Ibrahim Umar Garzali, Sami Akbulut, Ali Aloun, Motaz Naffa, Fuat Aksoy
Summary: This systematic review and meta-analysis compared the outcomes of DD-SLT and LDLT. The study included ten studies with a total of 4836 patients. The analysis showed that LDLT had higher overall survival rates at 1 year, 3 years, and 5 years compared to DD-SLT, and also had better graft survival rates at 3 years and 5 years.
WORLD JOURNAL OF GASTROINTESTINAL SURGERY
(2023)