An Outcome Model for Intravenous rt-PA in Acute Ischemic Stroke

Alteplase versus tenecteplase for thrombolysis after ischaemic stroke (ATTEST): a phase 2, randomised, open-label, blinded endpoint study

(2015) Xuya Huang et al.   LANCET NEUROLOGY

Improving early clinical trial phase identification of promising therapeutics

(2015) Thomas A. Kent et al.   NEUROLOGY

Stent-Retriever Thrombectomy after Intravenous t-PA vs. t-PA Alone in Stroke

(2015) Jeffrey L. Saver et al.   NEW ENGLAND JOURNAL OF MEDICINE

Randomized Assessment of Rapid Endovascular Treatment of Ischemic Stroke

(2015) Mayank Goyal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging Selection

(2015) Bruce C.V. Campbell et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke

(2015) Olvert A. Berkhemer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety and efficacy of uric acid in patients with acute stroke (URICO-ICTUS): a randomised, double-blind phase 2b/3 trial

(2014) Ángel Chamorro et al.   LANCET NEUROLOGY

Update on Intravenous Recombinant Tissue Plasminogen Activator for Acute Ischemic Stroke

(2014) Jennifer E. Fugate et al.   MAYO CLINIC PROCEEDINGS

Mild Hypothermia After Intravenous Thrombolysis in Patients With Acute Stroke

(2014) Katja Piironen et al.   STROKE

Hyperglycemia Worsens Outcome After rt-PA Primarily in the Large-Vessel Occlusive Stroke Subtype

(2014) Pitchaiah Mandava et al.   Translational Stroke Research

A Prospective, Randomized, Placebo-Controlled, Double-Blind Trial about Safety and Efficacy of Combined Treatment with Alteplase (rt-PA) and Cerebrolysin in Acute Ischaemic Hemispheric Stroke

(2013) Wilfried Lang et al.   International Journal of Stroke

Endovascular Treatment for Acute Ischemic Stroke

(2013) Alfonso Ciccone et al.   NEW ENGLAND JOURNAL OF MEDICINE

Endovascular Therapy after Intravenous t-PA versus t-PA Alone for Stroke

(2013) Joseph P. Broderick et al.   NEW ENGLAND JOURNAL OF MEDICINE

Quantification of Errors in Ordinal Outcome Scales Using Shannon Entropy: Effect on Sample Size Calculations

(2013) Pitchaiah Mandava et al.   PLoS One

Combined Approach to Lysis Utilizing Eptifibatide and Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke–Enhanced Regimen Stroke Trial

(2013) Arthur M. Pancioli et al.   STROKE

Fast Neuroprotection (Fast-NPRX) for Acute Ischemic Stroke Victims: the Time for Treatment Is Now

(2013) Paul A. Lapchak   Translational Stroke Research

Citicoline in the treatment of acute ischaemic stroke: an international, randomised, multicentre, placebo-controlled study (ICTUS trial)

(2012) Antoni Dávalos et al.   LANCET

Early administration of aspirin in patients treated with alteplase for acute ischaemic stroke: a randomised controlled trial

(2012) Sanne M Zinkstok et al.   LANCET

A Randomized Trial of Tenecteplase versus Alteplase for Acute Ischemic Stroke

(2012) Mark Parsons et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intensive Versus Subcutaneous Insulin in Patients With Hyperacute Stroke

(2012) Charlotte Rosso et al.   STROKE

The Albumin in Acute Stroke Part 1 Trial

(2011) Michael D. Hill et al.   STROKE

Effect of Intravenous Tirofiban and Aspirin in Reducing Short-Term and Long-Term Neurologic Deficit in Patients with Ischemic Stroke: A Double-Blind Randomized Trial

(2010) G. Torgano et al.   CEREBROVASCULAR DISEASES

Phase IIB/III Trial of Tenecteplase in Acute Ischemic Stroke

(2010) E. Clarke Haley et al.   STROKE

The Albumin in Acute Stroke (ALIAS) Multicenter Clinical Trial

(2010) Myron D. Ginsberg et al.   STROKE

A Pilot Trial of Low-Dose Intravenous Abciximab and Unfractionated Heparin for Acute Ischemic Stroke: Translating GP IIb/IIIa Receptor Inhibition to Clinical Practice

(2010) Pitchaiah Mandava et al.   Translational Stroke Research

Resolving the Negative Data Publication Dilemma in Translational Stroke Research

(2010) Paul A. Lapchak et al.   Translational Stroke Research

Transcranial ultrasound in clinical sonothrombolysis (TUCSON) trial

(2009) Carlos A. Molina et al.   ANNALS OF NEUROLOGY

Intra-arterial or intravenous thrombolysis for acute ischemic stroke? The SYNTHESIS pilot trial

(2009) A Ciccone et al.   Journal of NeuroInterventional Surgery

A Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Effects of a Targeted Exposure of Intravenous Repinotan in Patients With Acute Ischemic Stroke

(2009) Philip Teal et al.   STROKE

Recombinant Human Erythropoietin in the Treatment of Acute Ischemic Stroke

(2009) Hannelore Ehrenreich et al.   STROKE

A Method to Determine Stroke Trial Success Using Multidimensional Pooled Control Functions

(2009) Pitchaiah Mandava et al.   STROKE

Ancrod in Acute Ischemic Stroke

(2009) David E. Levy et al.   STROKE

Intravenous rt-PA versus endovascular therapy for acute ischemic stroke

(2008) Pitchaiah Mandava et al.   Current Atherosclerosis Reports

Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial

(2008) Stephen M Davis et al.   LANCET NEUROLOGY

Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

(2008) Werner Hacke et al.   NEW ENGLAND JOURNAL OF MEDICINE

The C ombined Approach to L ysis Utilizing E ptifibatide a nd r t-PA in Acute Ischemic Stroke

(2008) Arthur M. Pancioli et al.   STROKE

Emergency Administration of Abciximab for Treatment of Patients With Acute Ischemic Stroke: Results of an International Phase III Trial

(2007) Harold P. Adams et al.   STROKE