Article
Education & Educational Research
Philippe Robert, Felix Begin, Sasha Menard-Castonguay, Anne-Julie Frenette, Hector Quiroz-Martinez, Francois Lamontagne, Emilie-Prudence Belley-Cote, Frederick D'Aragon
Summary: Despite a positive attitude towards organ donation, medical students have limited knowledge on the subject. Findings suggest the necessity of a formal curriculum on organ donation for medical students.
BMC MEDICAL EDUCATION
(2021)
Article
Surgery
Babak J. Orandi, Rhiannon D. Reed, Haiyan Qu, Grace Owens, Sydney Brooks, A. Cozette Killian, Vineeta Kumar, Saulat S. Sheikh, Robert M. Cannon, Douglas J. Anderson, Cora E. Lewis, Jayme E. Locke
Summary: This study surveyed living kidney donors to understand their perspectives on follow-up laboratory testing. The completion of 6-month testing was strongly associated with the completion of 12-month testing. Donors who did not prioritize testing and forgot to get labs drawn until reminded were more likely to complete the testing.
CLINICAL TRANSPLANTATION
(2022)
Article
Public, Environmental & Occupational Health
Paul Boadu, Leah McLaughlin, Mustafa Al-Haboubi, Jennifer Bostock, Jane Noyes, Stephen O'Neill, Nicholas Mays
Summary: This study used machine learning to analyze data from 14,278 participants in the organ donation attitudinal tracker survey in the UK. The findings suggest that support for organ donation, awareness of campaigns, and younger age positively influence the intention to become a living kidney donor. Ethnic origin and religion have less predictive power in this regard. The results are valuable for developing interventions to increase living organ donation.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Surgery
Andrew Healey, Marcelo Cypel, Helen Pyle, Caitlin Mills, Jodie Heffren, David Katz, Justin Smith, Robert Teranishi, Susan Lavery, Janice Beitel, Janet MacLean, Dwight Prodger, Shaf Keshavjee, Jonathan C. Yeung
Summary: Donation of lungs following medical assistance in dying at home has shown to be feasible with excellent postoperative outcomes, and should be considered by transplant programs.
AMERICAN JOURNAL OF TRANSPLANTATION
(2021)
Article
Gastroenterology & Hepatology
Ehab E. Abdel-Khalek, Mohamed Abdel-Wahab, Mohamed H. Elgazzar, Mahmoud A. Khattab, Abdel-Hady El-Gilany, Hesham M. Elgouhari, Ahmed Shehta
Summary: This study examined the long-term health consequences of living liver donation and found that living liver donors had lower scores in physical functioning, role limitations, energy/fatigue, and bodily pain compared to non-donors. However, donors whose recipients received a liver transplant had higher scores on health-related quality of life measures.
LIVER TRANSPLANTATION
(2022)
Review
Immunology
Tiyi Morris, Hannah Maple, Sam Norton, Joseph Chilcot, Lisa Burnapp, Heather Draper, Nizam Mamode, Paul McCrone
Summary: End-stage kidney disease is a burden on healthcare systems, with transplantation offering significant benefit over dialysis but facing a shortage of donor kidneys. This article provides an economic perspective on living kidney donation and transplantation, discussing policy recommendations to address supply and demand issues.
Article
Immunology
Leyla R. Herbst, Kayleigh Herrick-Reynolds, Laura Bowles Zeiser, Julia Lopez, Amber Kernodle, Awura Asamoah-Mensah, Tanjala Purnell, Dorry L. Segev, Allan B. Massie, Elizabeth King, Jacqueline Garonzik-Wang, Andrew M. Cameron
Summary: This study found that the number of living donor liver transplants, including those from NDDs, has been increasing over the past decade but remains concentrated at few centers. Adult and pediatric recipients of NDD liver transplants were more frequently female and diagnosed with biliary atresia. There were no observed racial inequities in the distribution of NDD grafts at different centers for adult or pediatric patients.
Article
Health Care Sciences & Services
Yijin Wu, Mengzhen Li, Linzi Li
Summary: This study examines the knowledge and attitudes of Chinese non-medical university students towards living organ donation. The findings indicate that most students have positive attitudes towards living organ donation, but they are concerned about the potential impact on their own health.
JOURNAL OF MULTIDISCIPLINARY HEALTHCARE
(2022)
Article
Medicine, General & Internal
Kim Wiebe, Lindsay C. Wilson, Ken Lotherington, Caitlin Mills, Sam D. Shemie, James Downar
Summary: Since 2019, Canadian Blood Services has developed policy guidance for organ and tissue donation after medical assistance in dying (MAiD), and the federal government has made changes to related legislation. This document provides updated guidance for healthcare professionals and policy-makers on the impact of these changes, addressing various topics such as referral, consent, and determination of death.
CANADIAN MEDICAL ASSOCIATION JOURNAL
(2023)
Article
Immunology
Hyunjae Im, Eun Jin Jang, Junwoo Jo, Suk Hyung Choe, Somin Joo, Hannah Lee, Seung-Young Oh, Suk Kyun Hong, Ho Geol Ryu
Summary: This study assessed healthcare resource utilization in living liver donors after donation and found that healthcare resource utilization was higher in living liver donors compared to matched nondonors for up to 5 years after donation.
Article
Ethics
Maximilian Kiener
Summary: This paper argues that in the context of living organ donation, voluntariness should not be equated with willingness, does not require the exercise of relational moral agency, and in cases of third-party pressure, the role of the surgeon and the medical team is critical. The author emphasizes that an adequate account of voluntary consent must take into consideration individuals pursuing different conceptions of the good and the interaction between the person giving consent and the person receiving consent.
JOURNAL OF MEDICAL ETHICS
(2021)
Article
Public, Environmental & Occupational Health
Xiaojing Fan, Meng Li, Heike Rolker, Yingying Li, Jiaoyang Du, Duolao Wang, Enchang Li
Summary: This study assessed the level of knowledge, attitudes, and willingness to organ donation among the general public in China. The findings revealed a positive association between knowledge and attitudes with the Chinese general public's willingness to organ donation. Understanding the concept of brain death and the transplant procedure may help increase the rate of willingness to organ donation.
Review
Ethics
Daniel Rodger, Bonnie Venter
Summary: Every year in England, many patients die while waiting for a kidney transplant, indicating that the current altruistic-based donation system is insufficient to address the kidney shortage. To tackle this problem, we propose a monopsony system where kidney donors can choose to receive financial compensation. By doing so, numerous lives could be saved, waiting times for transplants could be reduced, and the burden on dialysis services could be lessened. Additionally, compensation would help overcome disincentives to donation and increase awareness of living kidney donation, while also resulting in cost savings for healthcare.
MEDICINE HEALTH CARE AND PHILOSOPHY
(2023)
Article
Surgery
Tatsuaki Watanabe, Mitsuaki Kawashima, Mikihiro Kohno, Jonathan Yeung, James Downar, Andrew Healey, Tereza Martinu, Meghan Aversa, Laura Donahoe, Andrew Pierre, Marc de Perrot, Kazuhiro Yasufuku, Thomas K. Waddell, Shaf Keshavjee, Marcelo Cypel
Summary: This study compared lung transplantation outcomes using medical assisting in dying (MAID) donors and neurologically determined death and controlled donation after circulatory death (NDD/cDCD) donors. The results showed excellent recipient outcomes for lung transplantation using MAID donors, with similar intermediate-term outcomes compared to other types of donors. Therefore, donation after MAID should be strongly considered for lung transplantation where permitted.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
Article
Gastroenterology & Hepatology
Abdullah Kisaoglu, Volkan Dogru, Vural Taner Yilmaz, Ismail Demiryilmaz, Ali Avanaz, Seyyit Muhsin Sarikaya, Bora Dinc, Bulent Aydinli
Summary: The study investigated the impact of preoperative platelet count and remnant liver volume ratio on posthepatectomy liver failure in living liver donors. After propensity score matching, a correlation was found between preoperative platelet count and the occurrence of postoperative liver failure in donors.
JOURNAL OF GASTROINTESTINAL SURGERY
(2022)
Article
Medicine, General & Internal
A. Van Hecke, P. Van Bogaert, E. Decoene, F. Dobbels, E. Goossens, G. A. Goossens, S. Verhaeghe, T. Goffin
Summary: This article presents the new framework for Advanced Practice Nursing (APN) in Belgium and discusses the lack of clarity and current challenges. It emphasizes the need for further clarification and addresses several key questions regarding the role and responsibilities of APNs.
ACTA CLINICA BELGICA
(2022)
Article
Geriatrics & Gerontology
Ellen Vlaeyen, Joris Poels, Uschi Colemonts, Lien Peeters, Greet Leysens, Kim Delbaere, Eddy Dejaeger, Fabienne Dobbels, Koen Milisen
Summary: The study evaluated and compared the predictive accuracy of different screening methods for falls in nursing home residents. Fall history, FRiCA, and a CaHFRiS score of >= 4 showed better sensitivity and negative predictive value compared to clinical judgment. Specificity varied among the screening methods, with different positive predictive values at different time points.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2021)
Article
Surgery
Lieza Verhalle, Kristof Van Bockstaele, Nathalie Duerinckx, Jasper Vanhoof, Katrien Dierickx, Leen Neyens, Johan Van Cleemput, Sabine Gryp, Dominica Kums, Katleen De Bondt, Veronique Schaevers, Florian Demuynck, Anne Dewispelaere, Fabienne Dobbels
Summary: By conducting literature review, scoring, nursing pilot testing, cognitive debriefings with patients, a modified AUDIT-C was found to be suitable for identifying at-risk drinking in heart transplant patients, with further validation needed.
CLINICAL TRANSPLANTATION
(2021)
Article
Respiratory System
Judith Garcia-Aymerich, Milo A. Puhan, Solange Corriol-Rohou, Corina de Jong, Heleen Demeyer, Fabienne Dobbels, Damijan Erzen, Anja Frei, Elena Gimeno-Santos, Nicholas S. Hopkinson, Nathalie Ivanoff, Niklas Karlsson, Zafeiris Louvaris, Michael Polkey, Roberto A. Rabinovich, Mario Scuri, Maggie Tabberer, Ioannis Vogiatzis, Thierry Troosters
Summary: The D-PPAC and C-PPAC instruments showed strong internal consistency and construct validity in stable COPD patients, correlating with dyspnea, health-related quality of life and exercise capacity. Difficulty scores improved after pharmacological treatment and pulmonary rehabilitation, while amount scores improved after behavioral physical activity interventions.
Article
Cardiac & Cardiovascular Systems
Laurent Godinas, Fabienne Dobbels, Leni Hulst, Ive Verbeeck, Ines De Coninck, Pieter Berrevoets, Veronique Schaevers, Jonas Yserbyt, Lieven J. Dupont, Stijn E. Verleden, Bart M. Vanaudenaerde, Laurens J. Ceulemans, Dirk E. Van Raemdonck, Arne Neyrinck, Geert M. Verleden, Robin Vos
Summary: Conversion from twice daily to once daily tacrolimus in lung transplant patients requires close monitoring of tacrolimus trough levels. Post-conversion, once daily tacrolimus is safe with respect to renal function, metabolic parameters and allograft function, and improves patient adherence.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2021)
Article
Respiratory System
Anouk Delameillieure, Fabienne Dobbels, Sarah Vandekerkhof, Wim A. Wuyts
Summary: This study aimed to shed light on the care trajectory of patients with Idiopathic Pulmonary Fibrosis (IPF) based on the perspectives of patients and healthcare professionals. The findings identified pitfalls and suggestions for improvement at individual patient and care team levels, focusing on team-based care, pro-active follow-up, self-management support, and challenges related to eHealth tools. The importance of continuous training for professionals and collaboration with community-based organizations was also emphasized.
BMC PULMONARY MEDICINE
(2021)
Article
Psychiatry
Nathalie Duerinckx, Patrick J. Smith, Johan Vanhaecke, Sabina De Geest, Johan Van Cleemput, Steffi Lenaerts, Katrien Van Lommel, Fabienne Dobbels
Summary: The study showed that depressive symptoms at 1-year post-heart transplant can increase the risk of mortality and cardiac allograft vasculopathy, indicating the need for interventions to address this issue.
GENERAL HOSPITAL PSYCHIATRY
(2021)
Article
Oncology
Lynn Leppla, Anja Schmid, Sabine Valenta, Juliane Mielke, Sonja Beckmann, Janette Ribaut, Alexandra Teynor, Fabienne Dobbels, Nathalie Duerinckx, Robert Zeiser, Monika Engelhardt, Sabine Gerull, Sabina De Geest
Summary: This paper describes the development and application of an integrated care model for allogeneic stem cell transplantation facilitated by eHealth. The SMILe intervention consists of four self-management modules delivered partly face-to-face and partly via a mobile app. The new care model is currently being tested in an effectiveness-implementation trial.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Health Care Sciences & Services
Maan Isabella Cajita, Kris Denhaerynck, Lut Berben, Fabienne Dobbels, Johan Van Cleemput, Maria Crespo-Leiro, Jan Van Keer, Alain Jean Poncelet, Cynthia Russell, Sabina De Geest
Summary: The study found that heart transplant centers with high-degree chronic illness management had significantly higher mean survival rates at 1 year post-transplantation compared to centers with low-degree chronic illness management, but no differences were observed at other time points. Patients at high-degree chronic illness management centers had lower odds of moderate to severe drinking. There were no significant associations between the degree of chronic illness management and other recommended health behaviors.
Article
Criminology & Penology
Frederike Ambagtsheer
Summary: The global proliferation of human organ trafficking is not being met with a proportional number of prosecutions, with little research exploring the challenges and no existing studies using a criminal justice framework to explain these issues. Two cases, the Netcare case in South Africa and the Medicus case in Kosovo, involved globally operating criminal networks but faced different obstacles in investigation and prosecution. Recommendations for improving enforcement include better identification of suspicious activity, enhanced cross-border collaboration, and stronger protection for whistleblowers.
TRENDS IN ORGANIZED CRIME
(2021)
Article
Surgery
Ozgur Muhammet Koc, Marleen Pierco, Kathleen Remans, Thijs Van den Hende, Jef Verbeek, Hannah Van Malenstein, Schalk Van der Merwe, Geert Robaeys, Diethard Monbaliu, Jacques Pirenne, Bart Van den Bosch, Fabienne Dobbels, Frederik Nevens
Summary: Results of the study showed that liver transplant patients have a high willingness to participate in remote monitoring programs, and the implementation of remote monitoring is safe for chronic follow-up of adult liver transplant recipients. Remote monitoring also allowed for stringent follow-up of tacrolimus levels.
CLINICAL TRANSPLANTATION
(2022)
Review
Immunology
Barbora Kostalova, Janette Ribaut, Fabienne Dobbels, Sabine Gerull, Katerina Mala-Ladova, Leah L. Zullig, Sabina De Geest
Summary: This systematic review assesses the available information in randomized controlled trials (RCTs) supporting the clinical adoption of medication adherence interventions in adult transplant populations. The review finds that the RCTs tend to report limited implementation-relevant information, which hinders their translation to real-world transplant settings.
TRANSPLANTATION REVIEWS
(2022)
Article
Cardiac & Cardiovascular Systems
Martha Abshire Saylor, Kris Denhaerynck, Juliane Mielke, Patricia M. Davidson, Fabienne Dobbels, Cynthia L. Russell, Sabina De Geest
Summary: This study aimed to explore the variation in received emotional and practical social support among heart transplant recipients at the country and center levels, as well as assessing the multi-level correlates. The study found that social support varies at both the country and center levels and is associated with patient-level, micro-level, and meso-level factors.
EUROPEAN JOURNAL OF CARDIOVASCULAR NURSING
(2022)
Article
Criminology & Penology
Frederike Ambagtsheer, Roos Bugter
Summary: This study fills critical knowledge gaps regarding the organization of organ trade, revealing that illegal transplants require extensive preparations and high degree of organization, intersecting with the transplant industry and transport/hospitality sector.
CRIME LAW AND SOCIAL CHANGE
(2023)
Review
Respiratory System
Anouk Delameillieure, Sarah Vandekerkhof, Bastiaan Van Grootven, Wim A. Wuyts, Fabienne Dobbels
Summary: This systematic review identified 13 new care models or components developed for patients with idiopathic pulmonary fibrosis (IPF), focusing on team-based and multidisciplinary care provision and education. The most commonly described outcomes were related to health-related quality of life. Given the high demand for integrated care, developing and implementing new care models for patients with IPF should be a priority for research and clinical care.
RESPIRATORY RESEARCH
(2021)
