Article
Microbiology
Florian Fronhoffs, Leona Dold, Marijo Parcina, Arne Schneidewind, Maria Willis, Thomas F. E. Barth, Tobias J. Weismueller, Taotao Zhou, Philipp Lutz, Julian A. Luetkens, Peter Gerlach, Steffen Manekeller, Joerg C. Kalff, Tim O. Vilz, Christian P. Strassburg, Glen Kristiansen
Summary: Primary sclerosing cholangitis is a significant cause of liver transplantation. Hepatic alveolar echinococcosis, caused by Echinococcus multilocularis, can be detected by ultrasound or CT scan of the liver showing characteristic calcified conglomerates. Symptoms of alveolar echinococcosis occur after a long period of infection, accompanied by cholestasis or cholangitis. This report presents a case of presumed autoimmune hepatitis and primary sclerosing cholangitis in a patient, and post-transplantation diagnosis revealed alveolar echinococcosis in the explanted liver.
Review
Veterinary Sciences
Ian David Woolsey, Andrea L. Miller
Summary: Echinococcus spp. have a global distribution and are of significance to human and veterinary professionals. Infections can lead to different diseases, including cystic echinococcosis and alveolar echinococcosis.
RESEARCH IN VETERINARY SCIENCE
(2021)
Article
Gastroenterology & Hepatology
Jasmin Schuhbaur, Melissa Schweizer, Jana Philipp, Julian Schmidberger, Patrycja Schlingeloff, Wolfgang Kratzer
Summary: The sonomorphology of hepatic AE lesions may change over time, with hemangioma-like and pseudocystic patterns being affected.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Nanoscience & Nanotechnology
Jun Li, Yangyang Yang, Xiumin Han, Jing Li, Mengxiao Tian, Wenjing Qi, Huniu An, Chuanchuan Wu, Yao Zhang, Shuai Han, Liping Duan, Weisi Wang, Wenbao Zhang
Summary: In this study, PLGA nanoparticles encapsulating a novel anti-AE agent (H1402) were prepared for liver-targeted therapy of hepatic AE. The H1402-loaded nanoparticles showed efficient encapsulation, rapid penetration into the cyst wall, and extensive accumulation in the pre-cysts of E. multilocularis. The treatment with H1402-NPs resulted in significantly reduced parasitic burden compared to albendazole and untreated infected mice.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2023)
Review
Gastroenterology & Hepatology
Lynn Peters, Sanne Burkert, Beate Gruener
Summary: Liver parasites can lead to significant global morbidity, especially in Europe where their incidence is increasing due to climate change and globalisation. The correct diagnosis of hepatic parasites is often delayed because clinicians are unfamiliar with them, highlighting the importance of bringing attention to these neglected parasitic liver diseases.
JOURNAL OF HEPATOLOGY
(2021)
Article
Microbiology
Kira C. Steinkraus, Laila Joetten, Benno Traub, Marin Zaimi, Maximilian Denzinger, Christoph W. Michalski, Marko Kornmann, Felix J. Huettner
Summary: Alveolar echinococcosis (AE) is a rare disease that has been treated with robotic liver surgery for good short-term outcomes. In this study, 16 patients with AE underwent robotic hepatectomy, and the procedure was found to be safe and effective.
Article
Parasitology
Carlo Vittorio Citterio, Federica Obber, Karin Trevisiol, Debora Dellamaria, Roberto Celva, Marco Bregoli, Silvia Ormelli, Sofia Sgubin, Paola Bonato, Graziana Da Rold, Patrizia Danesi, Silvia Ravagnan, Stefano Vendrami, Davide Righetti, Andreas Agreiter, Daniele Asson, Andrea Cadamuro, Marco Ianniello, Gioia Capelli
Summary: A study conducted on 2872 foxes in Italy found a 7.55% prevalence of cestode eggs in fecal samples, with Echinococcus multilocularis, Taenia crassiceps, and Taenia polyacantha being the most common species. The study also revealed an increasing trend of E. multilocularis prevalence in recent years.
PARASITES & VECTORS
(2021)
Article
Microbiology
Ansgar Deibel, Cordula Meyer zu Schwabedissen, Lars Husmann, Felix Grimm, Peter Deplazes, Cacilia S. Reiner, Beat Muellhaupt
Summary: This study investigated the impact of immunosuppression-associated conditions (IACs) on the increase in new alveolar echinococcosis (AE) cases and the characteristics of AE at diagnosis and during clinical course. The findings suggest that IACs have little impact on the increase in new AE cases, as well as on the extent of the disease at diagnosis and clinical course.
Article
Microbiology
Jens Strohaeker, Mihaly Sulyok, Alfred Koenigsrainer, Silvio Nadalin
Summary: Liver resection remains the gold standard for treating AE, and even in extensive cases, complex surgeries combined with perioperative benzimidazoles can achieve favorable long-term outcomes.
Editorial Material
Acoustics
Wolfgang Kratzer, Henriette Weimer, Julian Schmidberger
Summary: This article discusses the diagnostic difficulties and pitfalls of alveolar echinococcosis and cystic echinococcosis based on case histories.
ULTRASCHALL IN DER MEDIZIN
(2022)
Article
Public, Environmental & Occupational Health
Junyan Qu, Huan Xu, Xiaoju Lv
Summary: Alveolar echinococcosis (AE) is a highly fatal and disabling parasitic infection with diverse clinical manifestations and difficulties in differential diagnosis. Metagenomic next-generation sequencing (mNGS) has become an attractive approach for the etiological diagnosis of infectious diseases. In this case, mNGS was used to diagnose disseminated AE, which can help improve clinicians' diagnostic skills.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Clinical Neurology
Sisi Li, Jiani Chen, Yongqiao He, Yongyi Deng, Jie Chen, Wenyu Fang, Zhamu Zeren, Yadong Liu, Ammar Taha Abdullah Abdulaziz, Bo Yan, Dong Zhou
Summary: Patients with intracranial alveolar echinococcosis (IAE) exhibit distinct clinical and radiological characteristics, with common neurological symptoms such as headache and liver involvement. Surgical treatment remains a major challenge, and poor compliance with albendazole is a concern in the treatment of IAE.
FRONTIERS IN NEUROLOGY
(2021)
Article
Infectious Diseases
Jana Philipp, Julian Schmidberger, Patrycja Schlingeloff, Wolfgang Kratzer
Summary: This study revealed significant differences in the behavior of hemangioma-like AE lesions and typical liver hemangiomas on CEUS. Early arterial bulbous ring enhancement and late-phase hyperenhancement were characteristic of hemangiomas, while hemangioma-like AE lesions showed typical early arterial rim enhancement followed by portal venous and late-phase non-enhancement. These findings highlight the importance of considering AE as a possible differential diagnosis in high-endemic areas.
Article
Immunology
Hui Wang, Chuan-Shan Zhang, Bin-Bin Fang, Jiao Hou, Wen-Ding Li, Zhi-De Li, Liang Li, Xiao-Juan Bi, Liang Li, Abuduaini Abulizi, Ying-Mei Shao, Ren-Yong Lin, Hao Wen
Summary: The study reveals that M2 macrophages dominate in hepatic macrophages associated with E. multilocularis infection. Macrophages in the liver tend to polarize towards the M1 phenotype at the early stage of infection, then shift to the M2 phenotype.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Immunology
Nosheen Basharat, Jadoon Khan, Irfan Ullah, Aamer Ali Shah, Ijaz Ali
Summary: In this study, the molecular characterization of human echinococcosis in the southern Punjab region of Pakistan was conducted. The majority of human infections were caused by E. granulosus s.s., followed by E. multilocularis and E. canadensis. Genotypic characterization among both human and livestock populations is needed to explore the genetic diversity of echinococcosis.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Letter
Clinical Neurology
Bahar Cankaya, Yasemin Ogul, Hayri Ogul, Mecit Kantarci
ACTA NEUROLOGICA BELGICA
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Erdal Tekin, Kutsi Tuncer, Ibrahim Ozlu, Recep Sade, Rustem Berhan Pirimoglu, Gokhan Polat
Summary: The study demonstrates that ultra-low-dose CT (ULDCT) provides high-quality images for suspected wrist fractures in the emergency department, reducing radiation dose by approximately 98% compared to standard-dose CT (SDCT) without impacting diagnostic accuracy.
Editorial Material
Surgery
Veysel Ayyildiz, Yener Aydin, Hayri Ogul
Summary: Tracheomalacia is a condition that is usually congenital in children but can also be acquired in rare cases in adults. Patients typically experience symptoms such as shortness of breath, chronic cough, and recurrent respiratory tract infections. Diagnosis is often incidentally made through thoracic imaging. This study presents a case of a 70-year-old female patient who developed tracheomalacia after tracheal intubation.
INDIAN JOURNAL OF SURGERY
(2023)
Article
Acoustics
Sonay Aydin, Oguzhan Tokur, Omer Kazci, Bunyamin Ece, Erdal Karavas, Mecit Kantarci
Summary: This research examines the association between COVID-19 infection and scrotal infection, finding that acute orchitis is more common in patients with higher clinical severity. Ultrasonography can help detect acute scrotal infection even in asymptomatic patients, particularly in those with more severe clinical presentations.
JOURNAL OF CLINICAL ULTRASOUND
(2022)
Article
Clinical Neurology
Elif Gozgec, Hayri Ogul, Hasan Durmus
Summary: Intraosseous arachnoid granulations (AGs) can be evaluated in detail with T2-SPACE imaging, which is superior to CT and conventional sequences. Determining the presence of intraosseous AGs is important for diagnosing idiopathic intracranial hypertension (IIH) and understanding their content.
ACTA NEUROLOGICA BELGICA
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Volkan Kizilgoz, Mecit Kantarci, Gokhan Tonkaz, Akin Levent, Hayri Ogul
Summary: MRI is widely used for detecting prostate cancer and guiding biopsy procedures. It can also detect incidental lesions, which can provide important information for diagnosis and early treatment. Awareness of congenital anomalies is crucial for radiologists.
Editorial Material
Otorhinolaryngology
Elif Gozgec, Hayri Ogul
ENT-EAR NOSE & THROAT JOURNAL
(2022)
Editorial Material
Otorhinolaryngology
Fahri Aydin, Veysel Ayyildiz, Elif Gozgec, Ali Koksal, Hayri Ogul, Mecit Kantarci
ENT-EAR NOSE & THROAT JOURNAL
(2022)
Editorial Material
Otorhinolaryngology
Fahri Aydin, Hayri Ogul, Mecit Kantarci
ENT-EAR NOSE & THROAT JOURNAL
(2022)
Article
Otorhinolaryngology
Elif Gozgec, Hayri Ogul, Muhammed S. Sakat
Summary: Osteomas in the middle ear cavity and incus are extremely rare, but common in the temporal bone. Computed tomography plays a crucial role in diagnosing this slowly growing benign bone tumor. Treatment options include follow-up and surgery based on the patient's condition.
ENT-EAR NOSE & THROAT JOURNAL
(2022)
Article
Otorhinolaryngology
Ali Koksal, Veysel Ayyildiz, Hayri Ogul, Mecit Kantarci
Summary: Perilymphatic fistula refers to the extravasation of perilymph fluid into the middle ear cavity. Cross-sectional imaging techniques play a crucial role in evaluating inner and middle ear structures and temporal bone. Thin section CT scans can effectively show pneumolabyrinth and temporal bone fractures, while high-resolution 3D volumetric MRI sequences can help demonstrate posttraumatic ear effusion and cerebrospinal fluid fistula in the inner or middle ear.
ENT-EAR NOSE & THROAT JOURNAL
(2022)
Article
Multidisciplinary Sciences
Volkan Kizilgoz, Mecit Kantarci, Sevket Kahraman
Summary: This study investigated the morphological variants of the Circle of Willis (COW) and explored the relationship between vessel calibers and COW integrity with gender and age groups.
SCIENTIFIC REPORTS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Suzan Bahadir, Sonay Aydin, Mecit Kantarci, Edhem Unver, Erdal Karavas, Duezguen Can Senbil
Summary: This study confirmed that TRO CTA is a comprehensive and feasible diagnostic tool in COVID-19 patients, helping to optimize diagnostic imaging strategies for thromboembolic events related to COVID-19.
WORLD JOURNAL OF RADIOLOGY
(2022)
Editorial Material
Medicine, General & Internal
Hayri Ogul, Serhat Kaya, Mecit Kantarci
BRITISH JOURNAL OF HOSPITAL MEDICINE
(2022)
Article
Otorhinolaryngology
Derya Guclu, Elif N. N. Unlu, Hayri Ogul
Summary: Nasopharyngeal stenosis is a rare condition that often develops as a result of nasopharyngeal or oropharyngeal surgery and radiotherapy. It can lead to obstructive symptoms and is usually diagnosed using nasopharyngoscopy. Treatment is challenging and involves various surgical techniques, such as balloon dilation. Even after successful surgery, recurrence is very common.
ENT-EAR NOSE & THROAT JOURNAL
(2022)
