Generation of minipigs with targeted transgene insertion by recombinase-mediated cassette exchange (RMCE) and somatic cell nuclear transfer (SCNT)

Expression pattern of a single transgene cassette located in endogenous GLIS3 of cloned pigs; a nested situation

(2012) Jannik Ejnar Jakobsen et al.   GENE

Genetic modifications of pigs for medicine and agriculture

(2011) Jeffrey J. Whyte et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Germline Transgenic Pigs by Sleeping Beauty Transposition in Porcine Zygotes and Targeted Integration in the Pig Genome

(2011) Wiebke Garrels et al.   PLoS One

Maternal endometrial oedema may increase perinatal mortality of cloned and transgenic piglets

(2011) M. Schmidt et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

The  F508 Mutation Causes CFTR Misprocessing and Cystic Fibrosis-Like Disease in Pigs

(2011) L. S. Ostedgaard et al.   Science Translational Medicine

Strategies for selection marker-free swine transgenesis using the Sleeping Beauty transposon system

(2011) Daniel F. Carlson et al.   TRANSGENIC RESEARCH

Elimination of the plasmid bacterial backbone in site-directed transgenesis

(2010) Jannik Jakobsen et al.   BIOTECHNIQUES

Establishment of a pig fibroblast-derived cell line for locus-directed transgene expression in cell cultures and blastocysts

(2010) Jannik E. Jakobsen et al.   MOLECULAR BIOLOGY REPORTS

A robust system for production of minicircle DNA vectors

(2010) Mark A Kay et al.   NATURE BIOTECHNOLOGY

Dual RMCE for efficient re-engineering of mouse mutant alleles

(2010) Marco Osterwalder et al.   NATURE METHODS

Efficient conditional and promoter-specific in vivo expression of cDNAs of choice by taking advantage of recombinase-mediated cassette exchange using FlEx gene traps

(2010) Laura Schebelle et al.   NUCLEIC ACIDS RESEARCH

Culture Conditions and Signalling Networks Promoting the Establishment of Cell Lines from Parthenogenetic and Biparental Pig Embryos

(2010) Tiziana A. L. Brevini et al.   Stem Cell Reviews and Reports

No shortcuts to pig embryonic stem cells

(2010) T.A.L. Brevini et al.   THERIOGENOLOGY

Pregnancies and piglets from large white sow recipients after two transfer methods of cloned and transgenic embryos of different pig breeds

(2010) M. Schmidt et al.   THERIOGENOLOGY

Pig transgenesis by Sleeping Beauty DNA transposition

(2010) Jannik E. Jakobsen et al.   TRANSGENIC RESEARCH

Efficient mammalian germline transgenesis by cis-enhanced Sleeping Beauty transposition

(2010) Daniel F. Carlson et al.   TRANSGENIC RESEARCH

ANALYSIS OF qPCR DATA BY CONVERTING EXPONENTIALLY RELATED Ct VALUES INTO LINEARLY RELATED X0 VALUES

(2010) RUNE THOMSEN et al.   Journal of Bioinformatics and Computational Biology

Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates

(2009) Lajos Mátés et al.   NATURE GENETICS

Hemizygous minipigs produced by random gene insertion and handmade cloning express the Alzheimer’s disease-causing dominant mutation APPsw

(2009) Peter M. Kragh et al.   TRANSGENIC RESEARCH

Production of CFTR-null and CFTR-ΔF508 heterozygous pigs by adeno-associated virus–mediated gene targeting and somatic cell nuclear transfer

(2008) Christopher S. Rogers et al.   JOURNAL OF CLINICAL INVESTIGATION

Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs

(2008) C. S. Rogers et al.   SCIENCE