Conditional inactivation of TGF-β type II receptor in smooth muscle cells and epicardium causes lethal aortic and cardiac defects

Absence of TGFβ signaling in embryonic vascular smooth muscle leads to reduced lysyl oxidase expression, impaired elastogenesis, and aneurysm

(2009) Bibha Choudhary et al.   GENESIS

Endoglin in angiogenesis and vascular diseases

(2008) Peter ten Dijke et al.   ANGIOGENESIS

TGF-β type I receptor Alk5 regulates tooth initiation and mandible patterning in a type II receptor-independent manner

(2008) Hu Zhao et al.   DEVELOPMENTAL BIOLOGY

Signaling via the Tgf-β type I receptor Alk5 in heart development

(2008) Somyoth Sridurongrit et al.   DEVELOPMENTAL BIOLOGY

Density-Dependent Shift of Transforming Growth Factor-Beta-1 from Inhibition to Stimulation of Vascular Smooth Muscle Cell Growth Is Based on Unconventional Regulation of Proliferation, Apoptosis and Contact Inhibition

(2008) Mohammad Hneino et al.   JOURNAL OF VASCULAR RESEARCH

Transforming Growth Factor-β Signaling in Thoracic Aortic Aneurysm Development: A Paradox in Pathogenesis

(2008) Jeffrey A. Jones et al.   JOURNAL OF VASCULAR RESEARCH

ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2

(2007) S. O. Park et al.   BLOOD