Impact of acellular hemoglobin-based oxygen carriers on brain apoptosis in rats

Redox Reactions of Hemoglobin: Mechanisms of Toxicity and Control

(2013) Todd L. Mollan et al.   ANTIOXIDANTS & REDOX SIGNALING

Both PI3K/Akt and ERK1/2 pathways participate in the protection by dexmedetomidine against transient focal cerebral ischemia/reperfusion injury in rats

(2012) Yong-Man Zhu et al.   BRAIN RESEARCH

Protection by silibinin against experimental ischemic stroke: Up-regulated pAkt, pmTOR, HIF-1α and Bcl-2, down-regulated Bax, NF-κB expression

(2012) Chaohui Wang et al.   NEUROSCIENCE LETTERS

Blood-Brain Barrier Disruption and Oxidative Stress in Guinea Pig after Systemic Exposure to Modified Cell-Free Hemoglobin

(2011) Omer I. Butt et al.   AMERICAN JOURNAL OF PATHOLOGY

A Systematic Review of Third-Generation Hydroxyethyl Starch (HES 130/0.4) in Resuscitation

(2011) Christiane S. Hartog et al.   ANESTHESIA AND ANALGESIA

Impact of Hemoglobin Concentration and Affinity for Oxygen on Tissue Oxygenation: The Case of Hemoglobin-Based Oxygen Carriers

(2011) Michele Samaja et al.   ARTIFICIAL ORGANS

Small-molecule inhibitors of the PI3K signaling network

(2011) Colleen R McNamara et al.   Future Medicinal Chemistry

A HIF-1 Target, ATIA, Protects Cells from Apoptosis by Modulating the Mitochondrial Thioredoxin, TRX2

(2011) Swati Choksi et al.   MOLECULAR CELL

Myocardial AKT: The Omnipresent Nexus

(2011) Mark A. Sussman et al.   PHYSIOLOGICAL REVIEWS

Phosphodiesterase-5 Inhibition Mimics Intermittent Reoxygenation and Improves Cardioprotection in the Hypoxic Myocardium

(2011) Giuseppina Milano et al.   PLoS One

Phosphorylation of phosphatidylinositol-3-kinase-protein kinase B and extracellular signal-regulated kinases 1/2 mediate reoxygenation-induced cardioprotection during hypoxia

(2010) Giuseppina Milano et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The Akt Pathway Is Involved in Rapid Ischemic Tolerance in Focal Ischemia in Rats

(2010) Xuwen Gao et al.   Translational Stroke Research

Hemospan Improves Outcome in a Model of Perioperative Hemodilution and Blood Loss in the Rat: Comparison With Hydroxyethyl Starch

(2009) Mark A. Young et al.   JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA

Early inhibition of HIF-1α with small interfering RNA reduces ischemic–reperfused brain injury in rats

(2009) Chunhua Chen et al.   NEUROBIOLOGY OF DISEASE

Regional Blood Flow After Serial Normovolemic Exchange Transfusion With HBOC-201 (Hemopure) in Anesthetized Swine

(2009) Paul D. Mongan et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Acellular haemoglobin attenuates hypoxia-inducible factor-1α (HIF-1α) and its target genes in haemodiluted rats

(2008) Dominador J. Manalo et al.   BIOCHEMICAL JOURNAL

Phosphodiesterase-5 Inhibition Abolishes Neuron Apoptosis Induced by Chronic Hypoxia Independently of Hypoxia-Inducible Factor-1α Signaling

(2008) Anna Caretti et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The Good, the Bad, and the Cell Type-Specific Roles of Hypoxia Inducible Factor-1  in Neurons and Astrocytes

(2008) G. Vangeison et al.   JOURNAL OF NEUROSCIENCE

Solution Structure of Poly(ethylene) Glycol-Conjugated Hemoglobin Revealed by Small-Angle X-Ray Scattering: Implications for a New Oxygen Therapeutic

(2007) Dmitri I. Svergun et al.   BIOPHYSICAL JOURNAL