Article
Veterinary Sciences
Eva Spada, Roberta Perego, Luciana Baggiani, Daniela Proverbio
Summary: This study assessed the effect of leukoreduction on the coagulation activity of canine plasma collected for transfusion. The results showed that leukoreduction resulted in a prolonged aPTT and reduced FXI activity, with no significant impact on other factors and parameters. Further studies with a larger sample size are needed to confirm these findings.
VETERINARY SCIENCES
(2021)
Article
Agriculture, Dairy & Animal Science
Maria Teresa Antognoni, Maria Luisa Marenzoni, Ambra Lisa Misia, Luca Avellini, Elisabetta Chiaradia, Alessandra Gavazza, Arianna Miglio
Summary: The study found that pre-storage leukoreduction can partially protect against storage lesions in blood units, emphasizing its importance for stored blood.
Article
Surgery
Ji-Hye Kwon, Sangbin Han, Doyeon Kim, Joon Hee Kuk, Hyun Cho, Seonwoo Kim, Ju Dong Yang, Chul Kim, Jong Man Kim, Gyu Sung Choi, Jae-Won Joh, Justin S. S. Ko, Mi Sook Gwak, Gaabsoo Kim
Summary: This study aimed to investigate the association between autotransfusion of salvaged blood with single leukoreduction and post-transplant tumor recurrence in patients with advanced hepatocellular carcinoma (HCC). The results showed that autotransfusion was not significantly related to HCC recurrence when matched with allogeneic transfusion, and autotransfusion may have potential benefits in patients with advanced HCC.
Article
Chemistry, Multidisciplinary
Murad A. A. Mubaraki, Hussain A. A. Almuayrifi, Taghreed A. Hafiz, Abdulaziz Alyousef, Mohamed A. A. Dkhil, Felwa A. A. Thagfan, Rewaida Abdel-Gaber, Mohammad A. A. Al-Najjar, Abdulsalam Alkhudhayri, Sherif Elshanat
Summary: This study evaluated the prevalence and trends of transfusion-transmitted infections (TTIs) in two hospitals in Riyadh and determined the best type of tests to ensure blood transfusion safety. Serological and nucleic acid tests (NAT) were performed on blood donors to screen for various infections. The study revealed the seriousness of the residual risk of TTI and suggested that utilizing NAT could improve blood safety and be cost-effective.
Article
Veterinary Sciences
Annalisa Stefani, Katia Capello, Antonio Carminato, Wendy Wurzburger, Tommaso Furlanello, Valentina Bertazzo, Elisabetta Marsilio, Elena Albertin, Giacomo La Pietra, Elisa Bozzato, Franco Mutinelli, Marta Vascellari
Summary: Leukoreduction was found to have positive effects on lactate, pH, and potassium levels in canine whole blood and blood products. It is recommended for critically ill dogs with marked inflammatory conditions.
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2021)
Article
Medicine, General & Internal
Nazish Saqlain, Naghmana Mazher, Sundas Arshad, Maha Sajjal
Summary: This study aimed to investigate the effects of donor and red blood cell concentrate characteristics on post-transfusion hemoglobin increment in pediatric patients. The results showed that donor age, Rh blood group, and washing of red blood cell concentrates significantly influenced the rise in recipient hemoglobin levels after transfusion.
PAKISTAN JOURNAL OF MEDICAL SCIENCES
(2022)
Article
Multidisciplinary Sciences
Samanta Grubyte, Jurgita Urboniene, Laura Nedzinskiene, Auguste Jelinskaite, Kestutis Zagminas, Arvydas Ambrozaitis, Ligita Jancoriene
Summary: The study analyzed data from the National Blood Center of Lithuania from 2004 to 2018 and found a decreasing trend in residual risk of HBV, HCV and HIV transmission among blood donors. Despite the decrease, the current risk remains quite high, indicating the need for a population screening program for transfusion transmitted viruses.
Article
Hematology
Marion Vermeulen, Ronel Swanevelder, Gert Van Zyl, Nico Lelie, Edward L. Murphy
Summary: The prevalence of HBV infection in blood donors born after the introduction of routine HBV immunization was significantly lower, indicating the effectiveness of the vaccination program. The contemporary residual risk of TT-HBV has decreased and is expected to further decline as more vaccinated young people become blood donors.
Article
Hematology
Thijs J. van de Laar, Boris M. Hogema, Marijke W. Molenaar-de Backer, Tanneke Marijt-van der Kreek, Hans L. Zaaijer
Summary: HBV donor screening in the Netherlands includes HBsAg screening, HBV DNA minipool testing, and anti-HBc screening. Among 5.5 million donations, 89 donors were identified as HBV-infected with at least two reactive HBV markers. Anti-HBc screening identified 1,067 potentially infectious donors with occult HBV infection.
Article
Multidisciplinary Sciences
Alex Mremi, James J. Yahaya, Mramba Nyindo, Edson Mollel
Summary: Blood transfusion saves many people every year, but the prevalence of common Transfusion-Transmitted Infections (TTIs) among blood donors in Tanzania is relatively high. HBV infection is the most common among blood donors, and replacement donors are at a higher risk of harboring TTIs.
Article
Hematology
Laura Tonnetti, Jamel A. Groves, Deanna Self, Manisha Yadav, Bryan R. Spencer, Kristin Livezey, Jeffrey M. Linnen, Susan L. Stramer
Summary: The Procleix Plasmodium Assay demonstrated high sensitivity and specificity in detecting Plasmodium RNA in an asymptomatic presenting donor, highlighting its potential as a screening test to reduce the number of deferred blood donors for malaria risk.
Review
Medicine, General & Internal
James Neuberger, Susan R. Brailsford, Gary Mallinson, Michael F. Murphy, Peter Simmonds
Summary: The supply of blood, blood products and components in the UK, as elsewhere, is safe, but not without risk. Measures to reduce risk, such as screening of donors and testing of donations, should be implemented. Improvement in the recognition, detection, reporting and investigation of cases of possible transfusion-transmitted infections is necessary. Properly informed consent should be obtained from blood recipients as transfusion is not risk-free.
Article
Public, Environmental & Occupational Health
Abdullah A. Mobarki, Maymoon M. Madkhali, Gasim Dobie, Muhammad Saboor, Aymen M. Madkhali, Basem Madkhli, Yahia Hummadi, Abdullah Meshi, Hesham M. Al-Mekhlafi, Mohammad S. Akhter, Hassan A. Hamali
Summary: The study evaluated the prevalence of HBV, HCV, and HIV among blood donors in Samtah General Hospital, Saudi Arabia, finding lower frequency of HBsAg, higher anti-HCV positivity, and uncommonness of HIV. Further research is needed to explore the cause of HCV infection in the area.
JOURNAL OF EPIDEMIOLOGY AND GLOBAL HEALTH
(2022)
Article
Hematology
Brandon S. S. Walker, Robert L. L. Schmidt, Sandra K. K. White, Ryan A. A. Metcalf
Summary: A systematic review and meta-analysis of published data on bacterial growth rates in stored platelets showed that the majority of doubling times were 1-5 hours. This updated analysis was used to refine a simulation model comparing the safety of bacterial risk control strategies.
Article
Medical Laboratory Technology
Sooin Choi, Soo Jeong Choi, Jeong Won Shin, Young Ahn Yoon
Summary: This study used CDM to estimate the compliance of SLP and found that SLPC tended to improve in most patient groups, but additional education and monitoring are needed for groups that continue to show low SLPC.
ANNALS OF LABORATORY MEDICINE
(2023)
Article
Biotechnology & Applied Microbiology
Xian-Yong Ma, Jian-Hui Wang, Jing-Lan Wang, Charles X. Ma, Xiao-Chun Wang, Feng-Song Liu
Meeting Abstract
Oncology
Xiaobin Gao, Jianhui Wang, Jinglan Wang, Lynnette Tumwine, Jeffrey Sklar
Article
Fisheries
Yili Wang, Ting Tang, Jihai Gu, Xiang Li, Xue Yang, Xiaobin Gao, Fengsong Liu, Jianhui Wang
FISH & SHELLFISH IMMUNOLOGY
(2015)
Article
Biochemistry & Molecular Biology
Yifu Gao, Ting Tang, Jihai Gu, Lingling Sun, Xiaobin Gao, Xianyong Ma, Xiaochun Wang, Fengsong Liu, Jianhui Wang
MOLECULAR IMMUNOLOGY
(2015)
Article
Oncology
Xianyong Ma, Jinglan Wang, Jianhui Wang, Charles X. Ma, Xiaobin Gao, Vytas Patriub, Jeffrey L. Sklar
Article
Multidisciplinary Sciences
Peng Chen, Ruixiang Xu, Jianhui Wang, Zhengrong Wu, Lei Yan, Wenbin Zhao, Yuheng Liu, Wantong Ma, Xiaofeng Shi, Hongyu Li
Article
Biotechnology & Applied Microbiology
Ruixiang Xu, Peng Song, Jianghui Wang, Zhengrong Wu, Lei Yan, Wenbin Zhao, Yuheng Liu, Wantong Ma, Maria Latta, Hongyu Li, Peng Chen
ELECTRONIC JOURNAL OF BIOTECHNOLOGY
(2019)
Article
Pharmacology & Pharmacy
Wantong Ma, Xue Li, Peng Song, Qianqian Zhang, Zhengrong Wu, Jianhui Wang, Xiaofeng Li, Ruixiang Xu, Wenbin Zhao, Yuheng Liu, Huanxiang Liu, Xiaojun Yao, Xiaoliang Tang, Peng Chen
EUROPEAN JOURNAL OF PHARMACOLOGY
(2019)
Article
Biochemistry & Molecular Biology
Nan Qin, Hehe Sun, Meike Lu, Jianhui Wang, Ting Tang, Fengsong Liu
JOURNAL OF BIOLOGICAL CHEMISTRY
(2020)
Article
Cell Biology
Yanke Chen, Ting Jiang, Hongyi Zhang, Xingchun Gou, Cong Han, Jianhui Wang, Ann T. Chen, Jun Ma, Jun Liu, Zeming Chen, Xintao Jing, Hong Lei, Zhenzhen Wang, Youmei Bao, Mehdi Baqri, Yong Zhu, Ranjit S. Bindra, James E. Hansen, Jun Dou, Chen Huang, Jiangbing Zhou
NATURE CELL BIOLOGY
(2020)
Review
Biotechnology & Applied Microbiology
Lei Yang, Jianhui Wang, Pei Hui, Timur O. Yarovinsky, Saiaditya Badeti, Kien Pham, Chen Liu
Summary: The COVID-19 pandemic caused by SARS-CoV-2 is spreading rapidly worldwide, and IFN-alpha is considered a potential therapeutic strategy, although its immunoregulatory effects may cause pathological damage and uncontrollable inflammation responses.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Tara Alpert, Anderson F. Brito, Erica Lasek-Nesselquist, Jessica Rothman, Andrew L. Valesano, Matthew J. MacKay, Mary E. Petrone, Mallery Breban, Anne E. Watkins, Chantal B. F. Vogels, Chaney C. Kalinich, Simon Dellicour, Alexis Russell, John P. Kelly, Matthew Shudt, Jonathan Plitnick, Erasmus Schneider, William J. Fitzsimmons, Gaurav Khullar, Jessica Metti, Joel T. Dudley, Megan Nash, Nike Beaubier, Jianhui Wang, Chen Liu, Pei Hui, Anthony Muyombwe, Randy Downing, Jafar Razeq, Stephen M. Bart, Ardath Grills, Stephanie M. Morrison, Steven Murphy, Caleb Neal, Eva Laszlo, Hanna Rennert, Melissa Cushing, Lars Westblade, Priya Velu, Arryn Craney, Lin Cong, David R. Peaper, Marie L. Landry, Peter W. Cook, Joseph R. Fauver, Christopher E. Mason, Adam S. Lauring, Kirsten St George, Duncan R. MacCannell, Nathan D. Grubaugh
Summary: The study found that the SARS-CoV-2 B.1.1.7 variant primarily spread in the United States through ports of entry in New York, California, and Florida, with multiple independent establishments starting in early December 2020 and interstate spread by the end of the month. It is projected that B.1.1.7 will become the dominant lineage in many states by mid- to late March, highlighting the urgent need to enhance genomic surveillance.
Article
Biochemistry & Molecular Biology
Chantal B. F. Vogels, Mallery I. Breban, Isabel M. Ott, Tara Alpert, Mary E. Petrone, Anne E. Watkins, Chaney C. Kalinich, Rebecca Earnest, Jessica E. Rothman, Jaqueline Goes de Jesus, Ingra Morales Claro, Giulia Magalhaes Ferreira, Myuki A. E. Crispim, Lavanya Singh, Houriiyah Tegally, Ugochukwu J. Anyaneji, Emma B. Hodcroft, Christopher E. Mason, Gaurav Khullar, Jessica Metti, Joel T. Dudley, Matthew J. MacKay, Megan Nash, Jianhui Wang, Chen Liu, Pei Hui, Steven Murphy, Caleb Neal, Eva Laszlo, Marie L. Landry, Anthony Muyombwe, Randy Downing, Jafar Razeq, Tulio de Oliveira, Nuno R. Faria, Ester C. Sabino, Richard A. Neher, Joseph R. Fauver, Nathan D. Grubaugh
Summary: With the emergence of SARS-CoV-2 variants with increased transmissibility and immune escape, targeted surveillance is urgently needed. The B.1.1.7 variant can be detected by a specific deletion in the spike gene, but other variants like B.1.351 and P.1 cannot. An open-source PCR assay targeting a deletion in the ORF1a gene has been designed and validated to enhance surveillance for these variants.
Article
Medicine, Research & Experimental
Chantal B. F. Vogels, Anne E. Watkins, Christina A. Harden, Doug E. Brackney, Jared Shafer, Jianhui Wang, Cesar Caraballo, Chaney C. Kalinich, Isabel M. Ott, Joseph R. Fauver, Eriko Kudo, Peiwen Lu, Arvind Venkataraman, Maria Tokuyama, Adam J. Moore, M. Catherine Muenker, Arnau Casanovas-Massana, John Fournier, Santos Bermejo, Melissa Campbell, Rupak Datta, Allison Nelson, Charles S. Dela Cruz, Albert Ko, Akiko Iwasaki, Harlan M. Krumholz, J. D. Matheus, Pei Hui, Chen Liu, Shelli F. Farhadian, Robby Sikka, Anne L. Wyllie, Nathan D. Grubaugh
Summary: SalivaDirect simplifies saliva-based diagnostic testing for SARS-CoV-2, demonstrating high positive agreement with traditional swab testing. This innovative approach can make large scale testing more accessible and affordable, offering an alternative solution to supply chain issues.
Article
Health Policy & Services
Rupali K. Doshi, J. Li, K. Dorsey, A. Allston, M. Kharfen
AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV
(2019)