Variable Processing and Cross-presentation of HIV by Dendritic Cells and Macrophages Shapes CTL Immunodominance and Immune Escape

Sequence-Specific Alterations of Epitope Production by HIV Protease Inhibitors

(2014) G. Kourjian et al.   JOURNAL OF IMMUNOLOGY

Mechanisms of HIV Protein Degradation into Epitopes: Implications for Vaccine Design

(2014) Marijana Rucevic et al.   Viruses-Basel

TCR Affinity Associated with Functional Differences between Dominant and Subdominant SIV Epitope-Specific CD8+ T Cells in Mamu-A*01+ Rhesus Monkeys

(2014) Christa E. Osuna et al.   PLoS Pathogens

A simple methodology to assess endolysosomal protease activity involved in antigen processing in human primary cells

(2013) Archana Vaithilingam et al.   BMC CELL BIOLOGY

Complement opsonization of HIV-1 results in a different intracellular processing pattern and enhanced MHC class I presentation by dendritic cells

(2013) Veronica Tjomsland et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A global approach to HIV-1 vaccine development

(2013) Kathryn E. Stephenson et al.   IMMUNOLOGICAL REVIEWS

A Blueprint for HIV Vaccine Discovery

(2012) Dennis R. Burton et al.   Cell Host & Microbe

Aminopeptidase Substrate Preference Affects HIV Epitope Presentation and Predicts Immune Escape Patterns in HIV-Infected Individuals

(2012) S. C. Zhang et al.   JOURNAL OF IMMUNOLOGY

HIV-1 Envelope Resistance to Proteasomal Cleavage: Implications for Vaccine Induced Immune Responses

(2012) Nicholas J. Steers et al.   PLoS One

Rapid Antigen Processing and Presentation of a Protective and Immunodominant HLA-B*27-restricted Hepatitis C Virus-specific CD8+ T-cell Epitope

(2012) Julia Schmidt et al.   PLoS Pathogens

Skin-Resident Murine Dendritic Cell Subsets Promote Distinct and Opposing Antigen-Specific T Helper Cell Responses

(2011) Botond Z. Igyártó et al.   IMMUNITY

Vaccine-Induced HIV-Specific CD8+ T Cells Utilize Preferential HLA Alleles and Target-Specific Regions of HIV-1

(2011) David Friedrich et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Variable HIV peptide stability in human cytosol is critical to epitope presentation and immune escape

(2011) Estibaliz Lazaro et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunodominance of HLA-A2-Restricted Hepatitis C Virus-Specific CD8+ T Cell Responses Is Linked to Naive-Precursor Frequency

(2011) J. Schmidt et al.   JOURNAL OF VIROLOGY

Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A

(2011) J. Idoyaga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The endosomal proteome of macrophage and dendritic cells

(2011) Sophie Duclos et al.   PROTEOMICS

The Antiviral Efficacy of HIV-Specific CD8+ T-Cells to a Conserved Epitope Is Heavily Dependent on the Infecting HIV-1 Isolate

(2011) Srinika R. F. Ranasinghe et al.   PLoS Pathogens

CD169-Positive Macrophages Dominate Antitumor Immunity by Crosspresenting Dead Cell-Associated Antigens

(2010) Kenichi Asano et al.   IMMUNITY

Route of Antigen Uptake Differentially Impacts Presentation by Dendritic Cells and Activated Monocytes

(2010) A. O. Kamphorst et al.   JOURNAL OF IMMUNOLOGY

HIV Immune Escape at an Immunodominant Epitope in HLA-B*27-Positive Individuals Predicts Viral Load Outcome

(2010) P. Ammaranond et al.   JOURNAL OF IMMUNOLOGY

Cell Type-Specific Proteasomal Processing of HIV-1 Gag-p24 Results in an Altered Epitope Repertoire

(2010) N. J. Steers et al.   JOURNAL OF VIROLOGY

Diverse regulatory roles for lysosomal proteases in the immune response

(2009) Jeff D. Colbert et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Kinetics of Expansion of Epitope-Specific T Cell Responses during Primary HIV-1 Infection

(2009) E. L. Turnbull et al.   JOURNAL OF IMMUNOLOGY

Differential HIV Epitope Processing in Monocytes and CD4 T Cells Affects Cytotoxic T Lymphocyte Recognition

(2009) Estibaliz Lazaro et al.   JOURNAL OF INFECTIOUS DISEASES

Adaptation of HIV-1 to human leukocyte antigen class I

(2009) Yuka Kawashima et al.   NATURE

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

(2009) Stefan Tenzer et al.   NATURE IMMUNOLOGY

The role of IFN-γ Elispot assay in HIV vaccine research

(2009) Hendrik Streeck et al.   Nature Protocols

Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity

(2009) N. van Montfoort et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentation

(2009) R. Belizaire et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Variable Fitness Impact of HIV-1 Escape Mutations to Cytotoxic T Lymphocyte (CTL) Response

(2009) Ryan M. Troyer et al.   PLoS Pathogens

NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells

(2008) A. R. Mantegazza et al.   BLOOD

The Exception that Reinforces the Rule: Crosspriming by Cytosolic Peptides that Escape Degradation

(2008) Avital Lev et al.   IMMUNITY

HLA-B57/B*5801 Human Immunodeficiency Virus Type 1 Elite Controllers Select for Rare Gag Variants Associated with Reduced Viral Replication Capacity and Strong Cytotoxic T-Lymphotye Recognition

(2008) T. Miura et al.   JOURNAL OF VIROLOGY

HLA-A*2402-restricted HIV-1-specific cytotoxic T lymphocytes and escape mutation after ART with structured treatment interruptions

(2008) Junko Tanuma et al.   MICROBES AND INFECTION