Inhibition and Reversal of Microbial Attachment by an Antibody with Parasteric Activity against the FimH Adhesin of Uropathogenic E. coli

Distinguishing induced fit from conformational selection

(2014) Stefano Gianni et al.   BIOPHYSICAL CHEMISTRY

Active site conformational changes upon reaction intermediate biotinyl-5'-AMP binding in biotin protein ligase fromMycobacterium tuberculosis

(2014) Qingjun Ma et al.   PROTEIN SCIENCE

Single molecule insights on conformational selection and induced fit mechanism

(2013) Nikos S. Hatzakis   BIOPHYSICAL CHEMISTRY

Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor

(2013) Susmith Mukund et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of pre-activated arrestin p44

(2013) Yong Ju Kim et al.   NATURE

A single-molecule dissection of ligand binding to a protein with intrinsic dynamics

(2013) Eunkyung Kim et al.   Nature Chemical Biology

Conformational inactivation induces immunogenicity of the receptor-binding pocket of a bacterial adhesin

(2013) D. I. Kisiela et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tamm-Horsfall Protein Regulates Circulating and Renal Cytokines by Affecting Glomerular Filtration Rate and Acting as a Urinary Cytokine Trap

(2012) Yan Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Observing force-regulated conformational changes and ligand dissociation from a single integrin on cells

(2012) Wei Chen et al.   JOURNAL OF CELL BIOLOGY

Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

(2011) Guillaume Lebon et al.   NATURE

The structural basis for agonist and partial agonist action on a β1-adrenergic receptor

(2011) Tony Warne et al.   NATURE

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

(2011) Søren G. F. Rasmussen et al.   NATURE

A Role for Both Conformational Selection and Induced Fit in Ligand Binding by the LAO Protein

(2011) Daniel-Adriano Silva et al.   PLoS Computational Biology

Structural Basis for Mechanical Force Regulation of the Adhesin FimH via Finger Trap-like β Sheet Twisting

(2010) Isolde Le Trong et al.   CELL

Conformational Changes and Ligand Recognition of Escherichia coli d-Xylose Binding Protein Revealed

(2010) Sanjeewani Sooriyaarachchi et al.   JOURNAL OF MOLECULAR BIOLOGY

Shear-enhanced binding of intestinal colonization factor antigen I of enterotoxigenicEscherichia coli

(2010) Veronika Tchesnokova et al.   MOLECULAR MICROBIOLOGY

Induced fit, conformational selection and independent dynamic segments: an extended view of binding events

(2010) Peter Csermely et al.   TRENDS IN BIOCHEMICAL SCIENCES

Shear-Enhanced Oral Microbial Adhesion

(2009) A. M. Ding et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Characterization of Inhibitory Anti-insulin-like Growth Factor Receptor Antibodies with Different Epitope Specificity and Ligand-blocking Properties

(2009) Adam Doern et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

A gate–latch–lock mechanism for hormone signalling by abscisic acid receptors

(2009) Karsten Melcher et al.   NATURE

The role of dynamic conformational ensembles in biomolecular recognition

(2009) David D Boehr et al.   Nature Chemical Biology

Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding

(2009) Swaine L. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrin-like Allosteric Properties of the Catch Bond-forming FimH Adhesin ofEscherichia coli

(2008) Veronika Tchesnokova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

(2008) X. Brochet et al.   NUCLEIC ACIDS RESEARCH

Intervening with Urinary Tract Infections Using Anti-Adhesives Based on the Crystal Structure of the FimH–Oligomannose-3 Complex

(2008) Adinda Wellens et al.   PLoS One

The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist

(2008) V.-P. Jaakola et al.   SCIENCE

Beyond Induced-Fit Receptor-Ligand Interactions: Structural Changes that Can Significantly Extend Bond Lifetimes

(2008) Lina M. Nilsson et al.   STRUCTURE