Interferon-α Subtypes in an Ex Vivo Model of Acute HIV-1 Infection: Expression, Potency and Effector Mechanisms

The molecular basis for functional plasticity in type I interferon signaling

(2015) Gideon Schreiber et al.   TRENDS IN IMMUNOLOGY

Interferons and viruses: an evolutionary arms race of molecular interactions

(2015) Hans-Heinrich Hoffmann et al.   TRENDS IN IMMUNOLOGY

Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression

(2014) Netanya G. Sandler et al.   NATURE

Immunoglobulin somatic hypermutation by APOBEC3/Rfv3 during retroviral infection

(2014) K. Halemano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbial exposure alters HIV-1-induced mucosal CD4+ T cell death pathways Ex vivo

(2014) Amanda K Steele et al.   Retrovirology

Reassessment of murine APOBEC1 as a retrovirus restriction factor in vivo

(2014) Bradley S. Barrett et al.   VIROLOGY

Human APOBEC3 Induced Mutation of Human Immunodeficiency Virus Type-1 Contributes to Adaptation and Evolution in Natural Infection

(2014) Eun-Young Kim et al.   PLoS Pathogens

CD141+ dendritic cells produce prominent amounts of IFN-  after dsRNA recognition and can be targeted via DEC-205 in humanized mice

(2013) S. Meixlsperger et al.   BLOOD

The Interferon-Inducible MxB Protein Inhibits HIV-1 Infection

(2013) Zhenlong Liu et al.   Cell Host & Microbe

IFN-  Treatment Inhibits Acute Friend Retrovirus Replication Primarily through the Antiviral Effector Molecule Apobec3

(2013) M. S. Harper et al.   JOURNAL OF IMMUNOLOGY

Longitudinal Analysis of Distribution and Function of Plasmacytoid Dendritic Cells in Peripheral Blood and Gut Mucosa of HIV Infected Patients

(2013) C. Lehmann et al.   JOURNAL OF INFECTIOUS DISEASES

Hepatitis C Therapy With Interferon-α and Ribavirin Reduces CD4 T-Cell–Associated HIV-1 DNA in HIV-1/Hepatitis C Virus–Coinfected Patients

(2013) Hong Sun et al.   JOURNAL OF INFECTIOUS DISEASES

Effects of Alpha Interferon Treatment on Intrinsic Anti-HIV-1 Immunity In Vivo

(2013) M. Abdel-Mohsen et al.   JOURNAL OF VIROLOGY

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

(2013) Caroline Goujon et al.   NATURE

MX2 is an interferon-induced inhibitor of HIV-1 infection

(2013) Melissa Kane et al.   NATURE

Phenotypic properties of transmitted founder HIV-1

(2013) N. F. Parrish et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Relative resistance of HIV-1 founder viruses to control by interferon-alpha

(2013) Angharad E Fenton-May et al.   Retrovirology

HIV Restriction Factors and Mechanisms of Evasion

(2013) M. H. Malim et al.   Cold Spring Harbor Perspectives in Medicine

IFN-α subtypes: distinct biological activities in anti-viral therapy

(2012) K Gibbert et al.   BRITISH JOURNAL OF PHARMACOLOGY

Expression profiles of human interferon-alpha and interferon-lambda subtypes are ligand- and cell-dependent

(2012) Philippa Hillyer et al.   IMMUNOLOGY AND CELL BIOLOGY

HIV-1 Infection of Human Intestinal Lamina Propria CD4+ T Cells In Vitro Is Enhanced by Exposure to Commensal Escherichia coli

(2012) S. M. Dillon et al.   JOURNAL OF IMMUNOLOGY

Pegylated Interferon Alfa-2a Monotherapy Results in Suppression of HIV Type 1 Replication and Decreased Cell-Associated HIV DNA Integration

(2012) Livio Azzoni et al.   JOURNAL OF INFECTIOUS DISEASES

Role of retroviral restriction factors in the interferon- -mediated suppression of HIV-1 in vivo

(2012) S. K. Pillai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon-alpha Subtype 11 Activates NK Cells and Enables Control of Retroviral Infection

(2012) Kathrin Gibbert et al.   PLoS Pathogens

Endogenous Origins of HIV-1 G-to-A Hypermutation and Restriction in the Nonpermissive T Cell Line CEM2n

(2012) Eric W. Refsland et al.   PLoS Pathogens

Structural variants of IFN  preferentially promote antiviral functions

(2011) N. Vazquez et al.   BLOOD

Blocking Type I Interferon Production: A New Therapeutic Option to Reduce the HIV-1-Induced Immune Activation

(2011) Moritz Ries et al.   Clinical & Developmental Immunology

Binding and activity of all human alpha interferon subtypes

(2011) Thomas B. Lavoie et al.   CYTOKINE

Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-α–producing and partially matured phenotype

(2011) Meagan O’Brien et al.   JOURNAL OF CLINICAL INVESTIGATION

Evolutionary genetic dissection of human interferons

(2011) Jérémy Manry et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

Innate Sensing of HIV-Infected Cells

(2011) Alice Lepelley et al.   PLoS Pathogens

Stromal Down-Regulation of Macrophage CD4/CCR5 Expression and NF-κB Activation Mediates HIV-1 Non-Permissiveness in Intestinal Macrophages

(2011) Ruizhong Shen et al.   PLoS Pathogens

Noninfectious Retrovirus Particles Drive the Apobec3/Rfv3 Dependent Neutralizing Antibody Response

(2011) Diana S. Smith et al.   PLoS Pathogens

Alpha interferon administration during structured interruptions of combination antiretroviral therapy in patients with chronic HIV-1 infection: INTERVAC ANRS 105 trial

(2010) François Boué et al.   AIDS

The differential activity of interferon-α subtypes is consistent among distinct target genes and cell types

(2010) Herwig P. Moll et al.   CYTOKINE

The Early Interferon Alpha Subtype Response in Infant Macaques Infected Orally With SIV

(2010) Juliet Easlick et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Safety, Tolerability, and Mechanisms of Antiretroviral Activity of Pegylated Interferon Alfa‐2a in HIV‐1–Monoinfected Participants: A Phase II Clinical Trial

(2010) David M. Asmuth et al.   JOURNAL OF INFECTIOUS DISEASES

APOBEC3G Contributes to HIV-1 Variation through Sublethal Mutagenesis

(2010) H. A. Sadler et al.   JOURNAL OF VIROLOGY

Blood Myeloid Dendritic Cells from HIV-1-Infected Individuals Display a Proapoptotic Profile Characterized by Decreased Bcl-2 Levels and by Caspase-3+ Frequencies That Are Associated with Levels of Plasma Viremia and T Cell Activation in an Exploratory Study

(2010) S. M. Dillon et al.   JOURNAL OF VIROLOGY

Measuring HIV fusion mediated by envelopes from primary viral isolates

(2010) Marielle Cavrois et al.   METHODS

Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction

(2010) Eric W. Refsland et al.   NUCLEIC ACIDS RESEARCH

Preferential Upregulation of Interferon-α Subtype 2 Expression in HIV-1 Patients

(2009) C. Lehmann et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Desensitization to type I interferon in HIV-1 infection correlates with markers of immune activation and disease progression

(2009) G. A. D. Hardy et al.   BLOOD

Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections

(2009) A. R. Stacey et al.   JOURNAL OF VIROLOGY

HIV Evolution in Early Infection: Selection Pressures, Patterns of Insertion and Deletion, and the Impact of APOBEC

(2009) Natasha Wood et al.   PLoS Pathogens

The Interferon-Induced Protein BST-2 Restricts HIV-1 Release and Is Downregulated from the Cell Surface by the Viral Vpu Protein

(2008) Nanette Van Damme et al.   Cell Host & Microbe

Rigid Interferon-α Subtype Responses of Human Plasmacytoid Dendritic Cells

(2008) Richard Szubin et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The DNA Deaminase Activity of Human APOBEC3G Is Required for Ty1, MusD, and Human Immunodeficiency Virus Type 1 Restriction

(2008) A. J. Schumacher et al.   JOURNAL OF VIROLOGY

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE

INTERFEROME: the database of interferon regulated genes

(2008) Shamith A. Samarajiwa et al.   NUCLEIC ACIDS RESEARCH

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

(2008) B. F. Keele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

APOBEC3G Inhibits Elongation of HIV-1 Reverse Transcripts

(2008) Kate N. Bishop et al.   PLoS Pathogens